Osong Public Health and Research Perspectives

Bridging innovation and policy: comparative pathways of national vaccine development in low- and middle-income countries: Vahid Marandi; Osong Public Health Res Perspect 2025;16(5):425-436.
Published online September 17, 2025; DOI: https://doi.org/10.24171/j.phrp.2025.0208

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Comparative effectiveness of construal-level messaging in the COVID-19 Vaccine Injury Compensation Program in the Republic of Korea: a randomized controlled trial: Jihyun Moon, Se-Hoon Jeong, Young June Choe, Cho Ryok Kang, Taemi Kim, Dooyoung Kim, Jong-Koo Lee; Osong Public Health Res Perspect 2025;16(5):486-497.
Published online September 12, 2025; DOI: https://doi.org/10.24171/j.phrp.2024.0354

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Immunoinformatics study of CD40 ligand-targeting vaccine constructs: a novel immunotherapeutic approach: Seyed Amir Sadeghi, Mahroo Mohamadi, Hadi Bamehr, Fatemeh Heidarnejad, Azam Bolhassani; Osong Public Health Res Perspect 2025;16(4):311-332.
Published online August 11, 2025; DOI: https://doi.org/10.24171/j.phrp.2025.0077

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Assessment of healthcare workers’ knowledge and attitudes toward mpox and acceptance of its vaccine: a health belief model-based analysis in the Gulf region: Mona Gamal Mohamed, Eman Abdelaziz Ahmed Dabou, Fatma M. Ibrahim, Shaimaa Abdelsamad, Jibin Kunjavara, Kamaruddeen Mannethodi, Moayad Ahmad Wishah, Abdullah Y. Shihab, Khaled Mohammed Al-Sayaghi, Hammad Ali Fadlalmola, Mohammed Musaed Al-Jabri; Osong Public Health Res Perspect 2025;16(4):357-372.
Published online June 25, 2025; DOI: https://doi.org/10.24171/j.phrp.2025.0113

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Knowledge and attitudes toward mpox among the Lebanese population during the second wave and their attitudes toward vaccination
Mohammad Tanashat, Nour Fakih, Nour El Bizri, Mohamed Saad Rakab, Mohamed Abouzid, Karen Sleiman, Hadi Hassan, Moetasem Al Sayed, Zahraa Zibara, Ahmad Afyouni, Pascale Salameh
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Decoding Vaccine Hesitancy in Mpox Across Multiple Middle Eastern Countries: Public Knowledge, Attitudes, Worry, Conspiracy Beliefs, and Acceptance
Mona Gamal Mohamed, Huda Mohamed Ali Rasheed, Manjula G. Bhagavathy, Moayad Ahmad Wishah, Dibbo Protim Ghosh, Md. Rabiul Islam, Ramya Kundayi Ravi
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Mpox Awareness and Infection Control Practices Among Hospital Nurses and Healthcare Workers in Bangladesh
Hemayet Hossain, Md. Abdur Nur Sakib, Mostafizor Rahman, Zerin Tasnim Romana, Md. Hasan Ali, Snigdha Sharmin Binte Sayeed, Khadiza Akter Brishty, Md. Shahidur Rahman Chowdhury, Md. Mahfujur Rahman
Public Health Challenges.2026;[Epub] CrossRef
Artificial intelligence and biohealth: the Republic of Korea’s emerging priorities in health care R&D
Jong-Koo Lee
Osong Public Health and Research Perspectives.2025; 16(4): 309. CrossRef
Nursing Students’ Knowledge, Attitudes, and Practices Toward Monkeypox Virus: A Cross-Sectional Survey at the University of Palermo, 2022
Barbara Ravazzolo, Francesco Leonforte, Letizia Cascio, Clara Ferrara, Federico Li Causi, Francesco Armetta, Maria Lampasona, Rinaldo Stefano Miceli, Carlo Fantini, Klara Komici, Alberto Firenze
Zoonotic Diseases.2025; 6(1): 1. CrossRef

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Design and evaluation of a multi-epitope subunit vaccine against human norovirus using an immunoinformatics approach: Zxcy L. Nonog, Edward C. Banico, Ma. Easter V. Sajo, Pablo V. Serrano, Fredmoore L. Orosco; Osong Public Health Res Perspect 2025;16(3):236-251.
Published online April 25, 2025; DOI: https://doi.org/10.24171/j.phrp.2024.0349

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Comparison and consideration of vaccine injury compensation programs in the Republic of Korea, Japan, and Taiwan: Cho Ryok Kang, Young June Choe, Jihyun Moon, Dooyoung Kim, Taemi Kim, Jong-Koo Lee; Osong Public Health Res Perspect 2024;15(6):479-488.
Published online November 12, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0129

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Safety of the bivalent COVID-19 mRNA booster vaccination among persons aged over 18 years in the Republic of Korea: Seok-Kyoung Choi, Seontae Kim, Mijeong Ko, Yeseul Heo, Tae Eun Kim, Yeonkyeong Lee, Juyeon Jang, Eunok Bahng; Osong Public Health Res Perspect 2024;15(6):542-549.
Published online October 29, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0194

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Methodology of comparative studies on the relative effectiveness of COVID-19 vaccines: a systematic review: Erdenetuya Bolormaa, Jiae Shim, Young-Sook Choi, Donghyok Kwon, Young June Choe, Seung-Ah Choe; Osong Public Health Res Perspect 2024;15(5):395-408.
Published online October 15, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0063

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Novel prophylactic and therapeutic multi-epitope vaccine based on Ag85A, Ag85B, ESAT-6, and CFP-10 of Mycobacterium tuberculosis using an immunoinformatics approach: Muhammad Fikri Nugraha, Daniel Alexander Changestu, Rizky Ramadhan, Tasya Salsabila, Arsila Nurizati, Sari Eka Pratiwi, Ysrafil Ysrafil; Osong Public Health Res Perspect 2024;15(4):286-306.
Published online July 26, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0026

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Shweta Tiwari, Ankit Kumar Singh, Aarshu Acharya, Joyabroto Ghosh, Rashmi Prabha Singh
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Genome-Guided Mining and Integrated in Silico Approach Uncover Potential of Streptomyces Secondary Metabolites as Multi-Target Agents Against Candida albicans Biofilm Formation
Ismail Ismail, Sylvia Utami Tunjung Pratiwi, Ema Damayanti, Jaka Widada, Ysrafil Ysrafil, Syamsu Nur, Abdul Halim Umar, Ira Handayani, Shanti Ratnakomala
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Domain arrangement–driven immunogenicity of a computationally designed mRNA vaccine targeting PPE68, IrtA, and PE9 of Mycobacterium tuberculosis
Theerawat Dobutr, Elena Stylianou, Helen McShane, Nawamin Pinpathomrat
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Ayesha Liaqat, Kubra Dastgir, Muhammad Sajjad, Hafiz Muzzammel Rehman, Muhammad Waheed Akhtar, Masoud Foroutan
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Computationally guided multi-epitope vaccine design targeting oncoprotein BZLF1, EBNA1, LMP1, and LMP2 for of EBV associated gastric cancer
Elvin Delonio, Ysrafil Ysrafil, Herlina Eka Shinta, Sari Eka Pratiwi
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Antigen 85B of Mycobacterium tuberculosis: From Immunodominant Antigen to Vaccine Candidate
Vivek Chauhan, Gaytri Mahajan, Rakesh Kumar, Shrikanth S. Gadad, Subhash C. Chauhan, Chinnaswamy Jagannath, Subramanian Dhandayuthapani
Vaccines.2026; 14(9): 811. CrossRef
Immunogenicity and protective efficacy of recombinant BCG expressing a multi-epitope vaccine against mycobacterium tuberculosis
Xuan-ji Zhang, Jia-rui Luo, Ting-ting Tian, Juan Shi, Zheng-long Chai, Chuang Li, Si-yu Zhang, Tao Qu, Feng-bo Zhang, Yue-jie Zhu
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Computational systems immunology and multi-scale modeling for the design of a Multi-Epitope Vaccine (MEV) against emerging multidrug-resistant Klebsiella michiganensis
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International Microbiology.2026;[Epub] CrossRef
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Mohammad J. Nasiri, Lily Rogowski, Vishwanath Venketaraman
Pathogens.2025; 14(4): 370. CrossRef
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Osnat Barazani, Thomas Erdos, Raafi Chowdhury, Gursimratpreet Kaur, Vishwanath Venketaraman
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In-silico epitope-based vaccines design: progress, challenges and the road ahead
Federica Cernuto, Avisa Maleki, Giulia Russo, Valentina Di Salvatore, Francesco Pappalardo
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Design of multi-epitope-based therapeutic vaccine candidates from HBc and HBx proteins of hepatitis B virus using reverse vaccinology and immunoinformatics approaches
Patricia Gita Naully, Marselina Irasonia Tan, Husna Nugrahapraja, Aluicia Anita Artarini, Reza Aditama, Ernawati Arifin Giri-Rachman, Sheikh Arslan Sehgal
PLOS ONE.2024; 19(12): e0313269. CrossRef

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Comparative safety of monovalent and bivalent mRNA COVID-19 booster vaccines in adolescents aged 12 to 17 years in the Republic of Korea: Mijeong Ko, Seontae Kim, Seok-Kyoung Choi, Seung Hwan Shin, Yeon-Kyeng Lee, Yunhyung Kwon; Osong Public Health Res Perspect 2024;15(4):364-374.
Published online July 9, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0081

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The COVID-19 Vaccine Safety Research Center: a cornerstone for strengthening safety evidence for COVID-19 vaccination in the Republic of Korea: Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Jaehun Jung, Joongyub Lee, Ju-Young Shin, Sun-Young Jung, Byung-Joo Park, Nam-Kyong Choi; Osong Public Health Res Perspect 2024;15(2):97-106.
Published online April 4, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0343

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Psychiatric adverse events associated with the COVID-19 vaccines approved in the Republic of Korea: a systematic review: Seungeun Ryoo, Miyoung Choi, Nam-Kyong Choi, Hyoung-Shik Shin, Jun Hee Woo, Byung-Joo Park, Sanghoon Oh; Osong Public Health Res Perspect 2024;15(2):107-114.
Published online March 28, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0325

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COVID-19 infection among people with disabilities in 2021 prior to the Omicron-dominant period in the Republic of Korea: a cross-sectional study: Seul-Ki Kang, Bryan Inho Kim; Osong Public Health Res Perspect 2024;15(2):150-158.
Published online March 28, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0194

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Challenges in capacity building of national immunization programs and emergency or pandemic vaccination responses in the Global Health Security Agenda member countries: Sookhyun Lee, Jung Ju Oh, Sang Hyun Park, Dasol Ro, Ye Jin Jeong, So Yoon Kim; Osong Public Health Res Perspect 2024;15(2):182-185.
Published online March 28, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0159

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Evaluation of COVID-19 vaccine effectiveness in different high-risk facility types during a period of Delta variant dominance in the Republic of Korea: a cross-sectional study: Min Jei Lee, Myung-Jae Hwang, Dong Seob Kim, Seon Kyeong Park, Jihyun Choi, Ji Joo Lee, Jong Mu Kim, Young-Man Kim, Young-Joon Park, Jin Gwack, Sang-Eun Lee; Osong Public Health Res Perspect 2023;14(5):418-426.
Published online October 19, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0188

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JYNNEOS vaccine safety monitoring in the Republic of Korea, 2022: a cross-sectional study: Jaeeun Lee, Seunghyun Lewis Kwon, Jinhee Park, Hyuna Bae, Hyerim Lee, Geun-Yong Kwon; Osong Public Health Res Perspect 2023;14(5):433-438.
Published online October 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0182

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Prevalence and patterns of adverse events following childhood immunization and the responses of mothers in Ile-Ife, South West Nigeria: a facility-based cross-sectional survey: Olorunfemi Akinbode Ogundele, Funmito Omolola Fehintola, Mubarak Salami, Rahmat Usidebhofoh, Mary Aderemi Abaekere; Osong Public Health Res Perspect 2023;14(4):291-299.
Published online July 27, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0071

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Temporal association between the age-specific incidence of Guillain-Barré syndrome and SARS-CoV-2 vaccination in Republic of Korea: a nationwide time-series correlation study: Hyunju Lee, Donghyok Kwon, Seoncheol Park, Seung Ri Park, Darda Chung, Jongmok Ha; Osong Public Health Res Perspect 2023;14(3):224-231.
Published online June 22, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0050

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Vaccine effectiveness and the epidemiological characteristics of a COVID-19 outbreak in a tertiary hospital in Republic of Korea: Seonhee Ahn, Tae Jong Son, Yoonsuk Jang, Jihyun Choi, Young Joon Park, Jiseon Seong, Hyun Hee Kwon, Muk Ju Kim, Donghyok Kwon; Osong Public Health Res Perspect 2023;14(3):188-196.
Published online June 8, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0066

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Effectiveness of the COVID-19 vaccine in the Honam region of the Republic of Korea: In-Sook Shin, Yong-Pyo Lee, Seung-Hoon Lee, Jae-Young Lee, Jong-Ha Park, Yoon-Seok Chung; Osong Public Health Res Perspect 2023;14(3):197-206.
Published online June 8, 2023; DOI: https://doi.org/10.24171/j.phrp.2022.0308

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The incidence and clinical characteristics of myocarditis and pericarditis following mRNA-based COVID-19 vaccination in Republic of Korea adolescents from July 2021 to September 2022: Ju-Young Sim, Seung-Yun Kim, Eun-Kyoung Kim; Osong Public Health Res Perspect 2023;14(2):76-88.
Published online April 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0032

Objectives
Age-specific information regarding myocarditis/pericarditis in adolescents following mRNA-based coronavirus disease 2019 (COVID-19) vaccination in Asia remains insufficient. This study investigated the incidence and clinical characteristics of myocarditis/pericarditis in Republic of Korea adolescents after mRNA-based COVID-19 vaccination.
Methods
This retrospective descriptive study utilized patient data from the Korea Immunization Management System. Incidence rates were calculated according to age and sex. Clinical characteristics (symptoms/signs, laboratory values, and imaging results) were compared between mild and severe cases.
Results
Between July 19, 2021 and September 30, 2022, 3,728,224 individuals aged 12 to 19 years received 6,484,165 mRNA-based COVID-19 vaccines, and 173 cases met the case definition for myocarditis/pericarditis: 151 mild (87.3%) and 22 severe (12.7%). The incidence was 3.8-fold higher in males than in females. Troponin I/ troponin T was elevated in 96% of myocarditis cases, demonstrating higher sensitivity than creatine kinase-myocardial band (67.6%) or C-reactive protein (75.2%). ST-segment or Twave on electrography abnormalities were found in 60.3% (85/141). Paroxysmal/sustained atrial/ventricular arrhythmias were more common in severe than in mild cases (45.5% vs. 16.8%, p=0.008). Edema on T2-weighted magnetic imaging occurred in 21.6% (8/37) and 62.5% (5/8) of mild and severe cases, respectively (p=0.03). Abnormal pericardial fluid collection or pericardial inflammation was found in 75.4% of pericarditis cases (49/65).
Conclusion
Myocarditis/pericarditis occurred in rare cases following mRNA-based COVID-19 vaccination. Most cases were mild, but the incidence was higher in adolescent males and after the second dose. As bivalent severe acute respiratory syndrome coronavirus 2 mRNA vaccination started in Republic of Korea in October 2022, the post-vaccination incidence of myocarditis/pericarditis should be closely monitored, considering clinical characteristics.

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COVID-19 outbreak in a religious village community in Republic of Korea and risk factors for transmission: Jiae Shim, Eunju Lee, Eunyoung Kim, Yeonhwa Choi, Giseok Kang, Bryan Inho Kim; Osong Public Health Res Perspect 2023;14(2):110-118.
Published online April 5, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0002

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A framework for nationwide COVID-19 vaccine safety research in the Republic of Korea: the COVID-19 Vaccine Safety Research Committee: Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi; Osong Public Health Res Perspect 2023;14(1):5-14.
Published online February 28, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0026

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The effectiveness of Paxlovid treatment in long-term care facilities in South Korea during the outbreak of the Omicron variant of SARS-CoV-2: Hanul Park, Young Joon Park, Hye Young Lee, Mi Yu, Yeong-Jun Song, Sang Eun Lee, Ji-Joo Lee, Eun-Sol Lee, Yeonjung Kim; Osong Public Health Res Perspect 2022;13(6):443-447.
Published online December 23, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0262

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