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Brief Report
Registration of Human Embryonic Stem Cell Lines: Korea, 2010
Ji-Yoon Lee, Dae-Yeon Lee, Young-Sil Choi, Kyoung-Jae Lee, Yong-Ou Kim
Osong Public Health Res Perspect. 2011;2(2):141-147.   Published online June 30, 2011
DOI: https://doi.org/10.1016/j.phrp.2011.07.002
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AbstractAbstract PDF
In an effort to increase the credibility of human embryonic stem cell (hESC) lines established in Korea, obligatory registration was introduced by the Bioethics and Safety Act 2008, effective as of January 1, 2010.The DNA fingerprint, chromosome stability, expression of pluripotency markers, and contamination of mycoplasma of the submitted lines were analyzed by Korea Centers for Disease Control and Prevention (KCDC). The characterization data and ethical aspects, such as informed consent for donation of surplus embryos, were reviewed by a 10-member advisory review committee for stem cell registry.A total of 55 domestic hESC lines were submitted for registration in 2010; among them 51 were registered. Among these submitted lines, 26 were additionally characterized by KCDC, while 25 lines previously characterized by the Ministry of Education, Science and Technology were not additionally analyzed by KCDC.Registration completed an oversight system for embryo research by registering the products of licensed embryo research projects, making embryo research more transparent in Korea. Information about hESC lines is available at the website of the Korea Stem Cell Registry (kscr.nih.go.kr).

Citations

Citations to this article as recorded by  
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  • Role of heat shock protein 60 in primed and naïve states of human pluripotent stem cells
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    Cells.2019; 8(12): 1530.     CrossRef
  • Progesterone Receptor Membrane Component 1 suppresses the p53 and Wnt/β-catenin pathways to promote human pluripotent stem cell self-renewal
    Ji Yea Kim, So Young Kim, Hong Seo Choi, Min Kyu Kim, Hyun Min Lee, Young-Joo Jang, Chun Jeih Ryu
    Scientific Reports.2018;[Epub]     CrossRef
  • hPSCreg—the human pluripotent stem cell registry
    Stefanie Seltmann, Fritz Lekschas, Robert Müller, Harald Stachelscheid, Marie-Sophie Bittner, Weiping Zhang, Luam Kidane, Anna Seriola, Anna Veiga, Glyn Stacey, Andreas Kurtz
    Nucleic Acids Research.2016; 44(D1): D757.     CrossRef

PHRP : Osong Public Health and Research Perspectives
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