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Original Article
- Evaluation of Drug Abuse Relapse Event Rate Over Time in Frailty Model
- Somaye Hosseini, Abbas Moghimbeigi, Ghodratollah Roshanaei, Farzaneh Momeniarbat
- Osong Public Health Res Perspect. 2014;5(2):92-95. Published online April 30, 2014
- DOI: https://doi.org/10.1016/j.phrp.2014.02.003
- 2,627 View
- 14 Download
- 9 Crossref
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Abstract
PDF - Objectives
Drug dependence as a chronic disorder is reversible over time and has a cost burden for individuals, families, and society. An individual who has stopped taking drugs for a long time may start taking drugs again. The variables affecting the reuse of drugs are not well known. Therefore a study of the factors that increase the length of time away from drugs is essential.
Methods
This study used data collected by the Bushehr addiction treatment centers (Tolloe and Pasargadae) from 100 men with drug addiction from March 2006 to September 2010. The shared frailty model was used to study the influence of variables on the duration of time away from drug use. The most common method for entering intra-class (personal) correlation is the survival frailty model, which uses parametric survival data for the evaluation of recurrent events. A Weibull distribution for time to event with gamma shared frailty was used.
Results
The mean (standard deviation) age and age at onset of opium use of the sample were 33.85 (8.11) and 20.65 (6.87), respectively. About 30% of the men studied had chronic disease and 36% had a mental illness. The mean (frequency mean) of the amount of opium used were 4.73 (3.8) g and 2.54 (1.14) times per day. The desire to end drug use was 97% and 3% for the men with drug addiction and their families, respectively, at the time when the men stopped using opium. The age at onset of opium use [p = 0.046, hazards ratio (HR) = 1.30], history of chronic disease (p = 0.005, HR = 249.635), and marital status (p = 0.06, HR = 0.027) are important in the reuse of opium.
Conclusion
We found that opium addiction is related to other chronic diseases and to the age at onset of opium use. A prospective study following up individuals with drug addiction who try to stop drug use in addiction treatment centers could help to determine the risk factors of resuming drug use. -
Citations
Citations to this article as recorded by
- Does substance use disorder treatment completion reduce the risk of treatment readmission in Chile?
José Ruiz-Tagle Maturana, Andrés González-Santa Cruz, Teresita Rocha-Jiménez, Álvaro Castillo-Carniglia
Drug and Alcohol Dependence.2023; 248: 109907. CrossRef - Long-term relapse prevention strategies among poly-substance users in Ghana: New insights for clinical practice
Richard Appiah
Journal of Ethnicity in Substance Abuse.2022; 21(3): 1104. CrossRef - Is the relapse concept in studies of substance use disorders a ‘one size fits all’ concept? A systematic review of relapse operationalisations
Fredrik D. Moe, Christian Moltu, James R. McKay, Sverre Nesvåg, Jone Bjornestad
Drug and Alcohol Review.2022; 41(4): 743. CrossRef - Evaluating drug use relapse event rate and its associated factors using Poisson model
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Farzaneh Momeniarbat, Javad Karimi, Nosrolah Erfani, Javad Kiani
Romanian Journal of Diabetes Nutrition and Metabol.2017; 24(2): 137. CrossRef - A Prospective Study to Investigate Predictors of Relapse among Patients with Opioid Use Disorder Treated with Methadone
Leen Naji, Brittany B. Dennis, Monica Bawor, Carolyn Plater, Guillaume Pare, Andrew Worster, Michael Varenbut, Jeff Daiter, David C. Marsh, Dipika Desai, Lehana Thabane, Zainab Samaan
Substance Abuse: Research and Treatment.2016; 10: SART.S37030. CrossRef - Survival Analysis of Drug Abuse Relapse in Addiction Treatment Centers
Aziz Kassani, Mohsen Niazi, Jafar Hassanzadeh, Rostam Menati
International Journal of High Risk Behaviors and A.2015;[Epub] CrossRef
- Does substance use disorder treatment completion reduce the risk of treatment readmission in Chile?
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