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Original Article
Aflatoxin M1 Contamination Levels in Cheeses Sold in Isfahan Province, Iran
Ali Sharifzadeh, Payam Ghasemi-Dehkordi, Mohsen Foroughi, Elham Mardanpour-Shahrekordi, Shahin Ramazi
Osong Public Health Res Perspect. 2017;8(4):260-263.   Published online August 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.4.05
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  • 25 Download
  • 15 Crossref
AbstractAbstract PDF
Objectives

Aflatoxin M1 (AFM1)-contaminated dairy products pose serious human health risks, causing liver and renal failure if consumed. They are also related to decreased milk and egg production in infected animals. This study investigated the AFM1 contamination levels in cheeses sold in Isfahan province, Iran, by enzyme-linked immunosorbent assay (ELISA).

Methods

A total of 100 white cheese samples were randomly collected from supermarkets in Isfahan province and after extraction using dichloromethane were prepared for the ELISA.

Results

Of the 100 samples, 52 (52%) were contaminated by AFM1, at levels ranging from 50.2 to 424.4 ng/kg. The remaining 48% of the samples had undetectable AFM1 levels (< 50 ng/kg). Based on the standard limit set by the European Commission and Iran, 8% (8/100) of the AFM1-positive samples (with concentrations between 250.2 and 424.4 ng/kg) had levels higher than the permissible value of 250 ng/kg.

Conclusion

Although the percentage of cheese samples in Isfahan province with AFM1 levels exceeding the national permissible limit was low, the examination of cheeses and the milk used for their production is nevertheless important for ensuring public health. Furthermore, optimum storage conditions of animal feed should be ensured, and livestock nutrition must be monitored for the presence of AFM1 and other aflatoxins.

Citations

Citations to this article as recorded by  
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    Journal of Food Composition and Analysis.2024; 129: 106124.     CrossRef
  • Current Status of Major Mycotoxins Contamination in Food and Feed in Asia─A Review
    Lu Sun, Runyan Li, Bowen Tai, Sarfaraz Hussain, Gang Wang, Xiumin Liu, Fuguo Xing
    ACS Food Science & Technology.2023; 3(2): 231.     CrossRef
  • A national systematic literature review for aflatoxin M1 in commonly consumed cheese brands in Iran: Human health risk assessment by Monte Carlo simulation
    Tooraj Massahi, Amir Kiani, Kiomars Sharafi, Abdullah Khalid Omer, Gholamreza Ebrahimzadeh, Jalil Jaafari, Nazir Fattahi, Kimya Parnoon
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  • Occurrence of aflatoxin M1 in milk and Minas Frescal cheese manufactured in Brazilian dairy plants
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    International Journal of Dairy Technology.2021; 74(2): 431.     CrossRef
  • Physical and Chemical Methods for Reduction in Aflatoxin Content of Feed and Food
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  • Aflatoxin M1 contamination level in Iranian milk and dairy products: a systematic review and meta-analysis
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    World Mycotoxin Journal.2020; 13(1): 67.     CrossRef
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    Comprehensive Reviews in Food Science and Food Saf.2020; 19(4): 2013.     CrossRef
  • Aflatoxin M1 in Nicaraguan and locally made hard white cheeses marketed in El Salvador
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    Toxicology Reports.2020; 7: 1157.     CrossRef
  • Incidence of aflatoxin M1 contamination in milk, white cheese, kashar and butter from Sakarya, Turkey
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    Food Science and Technology.2019; 39( suppl 1): 190.     CrossRef

PHRP : Osong Public Health and Research Perspectives