- Incubation Period of Ebola Hemorrhagic Virus Subtype Zaire
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Martin Eichner, Scott F. Dowell, Nina Firese
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Osong Public Health Res Perspect. 2011;2(1):3-7. Published online June 30, 2011
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DOI: https://doi.org/10.1016/j.phrp.2011.04.001
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Abstract
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- Objectives
Ebola hemorrhagic fever has killed over 1300 people, mostly in equatorial Africa. There is still uncertainty about the natural reservoir of the virus and about some of the factors involved in disease transmission. Until now, a maximum incubation period of 21 days has been assumed. Methods
We analyzed data collected during the Ebola outbreak (subtype Zaire) in Kikwit, Democratic Republic of the Congo, in 1995 using maximum likelihood inference and assuming a log-normally distributed incubation period. Results
The mean incubation period was estimated to be 12.7 days (standard deviation 4.31 days), indicating that about 4.1% of patients may have incubation periods longer than 21 days. Conclusion
If the risk of new cases is to be reduced to 1% then 25 days should be used when investigating the source of an outbreak, when determining the duration of surveillance for contacts, and when declaring the end of an outbreak.
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Citations to this article as recorded by
- Prevention and post-exposure management of occupational exposure to Ebola virus
Michael A Moso, Chuan K Lim, Eloise Williams, Caroline Marshall, James McCarthy, Deborah A Williamson The Lancet Infectious Diseases.2024; 24(2): e93. CrossRef - Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans
Kalani Ratnasiri, Hong Zheng, Jiaying Toh, Zhiyuan Yao, Veronica Duran, Michele Donato, Mario Roederer, Megha Kamath, John-Paul M. Todd, Matthew Gagne, Kathryn E. Foulds, Joseph R. Francica, Kizzmekia S. Corbett, Daniel C. Douek, Robert A. Seder, Shirit E Cell Reports.2024; 43(2): 113706. CrossRef - A comprehensive analysis of non-pharmaceutical interventions and vaccination on Ebolavirus disease outbreak: Stochastic modeling approach
Youngsuk Ko, Jacob Lee, Yubin Seo, Eunok Jung, Aleksandra Inic-Kanada PLOS Neglected Tropical Diseases.2024; 18(6): e0011955. CrossRef - Isothermal nucleic acid amplification technology for rapid detection of virus
Zhenting Wei, Xiaowen Wang, Huhu Feng, Fanpu Ji, Dan Bai, Xiaoping Dong, Wei Huang Critical Reviews in Biotechnology.2023; 43(3): 415. CrossRef - Predicting the combined effects of case isolation, safe funeral practices, and contact tracing during Ebola virus disease outbreaks
Aliou Bouba, Kristina Barbara Helle, Kristan Alexander Schneider, Jan Rychtář PLOS ONE.2023; 18(1): e0276351. CrossRef - Stability analysis of an SIR epidemic model with homestead-isolation on the susceptible and infectious, immunity, relapse and general incidence rate
Amine Bernoussi International Journal of Biomathematics.2023;[Epub] CrossRef - Path analysis method in an epidemic model and stability analysis
Yong Zhou, Yiming Ding, Minrui Guo Frontiers in Physics.2023;[Epub] CrossRef - Tradeoff between speed and reproductive number in pathogen evolution
Andreas Eilersen, Bjarke Frost Nielsen, Kim Sneppen Physical Review Research.2023;[Epub] CrossRef - A Reinforcement Learning Based Decision Support Tool for Epidemic Control: Validation Study for COVID-19
Mohamed-Amine Chadi, Hajar Mousannif Applied Artificial Intelligence.2022;[Epub] CrossRef - Spatially-heterogeneous embedded stochastic SEIR models for the 2014–2016 Ebola outbreak in West Africa
Kaitlyn Martinez, Grant Brown, Stephen Pankavich Spatial and Spatio-temporal Epidemiology.2022; 41: 100505. CrossRef - Staff Scheduling During a Pandemic: The Case of Radiation Therapy Department
Hossein Abouee Mehrizi, Arian Aminoleslami, Johnson Darko, Ernest Osei, Houra Mahmoudzadeh SSRN Electronic Journal .2022;[Epub] CrossRef - Review of Ebola virus disease in children – how far have we come?
Devika Dixit, Kasereka Masumbuko Claude, Lindsey Kjaldgaard, Michael T. Hawkes Paediatrics and International Child Health.2021; 41(1): 12. CrossRef - Multi-population stochastic modeling of Ebola in Sierra Leone: Investigation of spatial heterogeneity
Rachid Muleia, Marc Aerts, Christel Faes, Maria Vittoria Barbarossa PLOS ONE.2021; 16(5): e0250765. CrossRef - Detecting Pathogen Exposure During the Non-symptomatic Incubation Period Using Physiological Data: Proof of Concept in Non-human Primates
Shakti Davis, Lauren Milechin, Tejash Patel, Mark Hernandez, Greg Ciccarelli, Siddharth Samsi, Lisa Hensley, Arthur Goff, John Trefry, Sara Johnston, Bret Purcell, Catherine Cabrera, Jack Fleischman, Albert Reuther, Kajal Claypool, Franco Rossi, Anna Honk Frontiers in Physiology.2021;[Epub] CrossRef - Advances and insights in the diagnosis of viral infections
Julija Dronina, Urte Samukaite-Bubniene, Arunas Ramanavicius Journal of Nanobiotechnology.2021;[Epub] CrossRef - Treatment of Ebola-related critical illness
Peter Kiiza, S. Mullin, K. Teo, N. K. J. Adhikari, R. A. Fowler Intensive Care Medicine.2020; 46(2): 285. CrossRef - AAV Vectored Immunoprophylaxis for Filovirus Infections
Amira D. Rghei, Laura P. van Lieshout, Lisa A. Santry, Matthew M. Guilleman, Sylvia P. Thomas, Leonardo Susta, Khalil Karimi, Byram W. Bridle, Sarah K. Wootton Tropical Medicine and Infectious Disease.2020; 5(4): 169. CrossRef - Vaccination strategies to control Ebola epidemics in the context of variable household inaccessibility levels
Gerardo Chowell, Amna Tariq, Maria Kiskowski, Benjamin Althouse PLOS Neglected Tropical Diseases.2019; 13(11): e0007814. CrossRef - Application of the CDC EbolaResponse Modeling tool to disease predictions
Robert H. Gaffey, Cécile Viboud Epidemics.2018; 22: 22. CrossRef - A mathematical model with isolation for the dynamics of Ebola virus
Amira Rachah Journal of Physics: Conference Series.2018; 1132: 012058. CrossRef - Multiscale model for pedestrian and infection dynamics during air travel
Sirish Namilae, Pierrot Derjany, Anuj Mubayi, Mathew Scotch, Ashok Srinivasan Physical Review E.2017;[Epub] CrossRef - Modeling ebola virus disease transmissions with reservoir in a complex virus life ecology
Tsanou Berge, Samuel Bowong, Jean Lubuma, Martin Luther Mann Manyombe Mathematical Biosciences and Engineering.2017; 15(1): 21. CrossRef - Application of a quantitative entry assessment model to compare the relative risk of incursion of zoonotic bat-borne viruses into European Union Member States
Verity Horigan, Paul Gale, Rowena D. Kosmider, Christopher Minnis, Emma L. Snary, Andrew C. Breed, Robin R.L. Simons Microbial Risk Analysis.2017; 7: 8. CrossRef - Multigroup deterministic and stochastic SEIRI epidemic models with nonlinear incidence rates and distributed delays: A stability analysis
Hong Zhang, Juan Xia, Paul Georgescu Mathematical Methods in the Applied Sciences.2017; 40(18): 6254. CrossRef - Modeling spatial invasion of Ebola in West Africa
Jeremy P. D’Silva, Marisa C. Eisenberg Journal of Theoretical Biology.2017; 428: 65. CrossRef - The potential impact of a prophylactic vaccine for Ebola in Sierra Leone
Erin N. Bodine, Connor Cook, Mikayla Shorten Mathematical Biosciences and Engineering.2017; 15(2): 337. CrossRef - Ebola virus – from neglected threat to global emergency state
Daniela Alexandra de Meneses Rocha Aguiar Pacheco, Acácio Agostinho Gonçalves Rodrigues, Carmen Maria Lisboa da Silva Revista da Associação Médica Brasileira.2016; 62(5): 458. CrossRef - Neglected filoviruses
Robin Burk, Laura Bollinger, Joshua C. Johnson, Jiro Wada, Sheli R. Radoshitzky, Gustavo Palacios, Sina Bavari, Peter B. Jahrling, Jens H. Kuhn, Urs Greber FEMS Microbiology Reviews.2016; 40(4): 494. CrossRef - Treatment–donation-stockpile dynamics in ebola convalescent blood transfusion therapy
Xi Huo, Xiaodan Sun, Kunquan Lan, Jianhong Wu Journal of Theoretical Biology.2016; 392: 53. CrossRef - Ebola virus disease in nonendemic countries
Samson Sai-Yin Wong, Sally Cheuk-Ying Wong Journal of the Formosan Medical Association.2015; 114(5): 384. CrossRef - Ebola Hemorrhagic Fever
Maryam Keshtkar Jahromi, Batool Sharifi Mood International Journal of Infection.2015;[Epub] CrossRef - Tactics and Strategies for Managing Ebola Outbreaks and the Salience of Immunization
Wayne M. Getz, Jean-Paul Gonzalez, Richard Salter, James Bangura, Colin Carlson, Moinya Coomber, Eric Dougherty, David Kargbo, Nathan D. Wolfe, Nadia Wauquier Computational and Mathematical Methods in Medicine.2015; 2015: 1. CrossRef - What is Ebola?
R. A. Stein International Journal of Clinical Practice.2015; 69(1): 49. CrossRef - Ebola virus disease outbreak in Nigeria: Transmission dynamics and rapid control
C.L. Althaus, N. Low, E.O. Musa, F. Shuaib, S. Gsteiger Epidemics.2015; 11: 80. CrossRef - A review of epidemiological parameters from Ebola outbreaks to inform early public health decision-making
Maria D. Van Kerkhove, Ana I. Bento, Harriet L. Mills, Neil M. Ferguson, Christl A. Donnelly Scientific Data.2015;[Epub] CrossRef - Modeling Post-death Transmission of Ebola: Challenges for Inference and Opportunities for Control
Joshua S. Weitz, Jonathan Dushoff Scientific Reports.2015;[Epub] CrossRef - Transmission Models of Historical Ebola Outbreaks
John M. Drake, Iurii Bakach, Matthew R. Just, Suzanne M. O’Regan, Manoj Gambhir, Isaac Chun-Hai Fung Emerging Infectious Diseases.2015; 21(8): 1447. CrossRef - Theoretical perspectives on the infectiousness of Ebola virus disease
Hiroshi Nishiura, Gerardo Chowell Theoretical Biology and Medical Modelling.2015;[Epub] CrossRef - Effect of Ebola Progression on Transmission and Control in Liberia
Dan Yamin, Shai Gertler, Martial L. Ndeffo-Mbah, Laura A. Skrip, Mosoka Fallah, Tolbert G. Nyenswah, Frederick L. Altice, Alison P. Galvani Annals of Internal Medicine.2015; 162(1): 11. CrossRef - Transmission dynamics and control of Ebola virus disease (EVD): a review
Gerardo Chowell, Hiroshi Nishiura BMC Medicine.2014;[Epub] CrossRef - Analysis of Ebolavirus with Decision Tree and Apriori algorithm
Eunby Go, Seungmin Lee, Taeseon Yoon International Journal of Machine Learning and Comp.2014; 4(6): 543. CrossRef - Calculation of incubation period and serial interval from multiple outbreaks of Marburg virus disease
Boris I Pavlin BMC Research Notes.2014; 7(1): 906. CrossRef - Outbreaks of Ebola virus disease in Africa: the beginnings of a tragic saga
Jean-Philippe Chippaux Journal of Venomous Animals and Toxins including T.2014; 20(1): 44. CrossRef - Association between temperature, humidity and ebolavirus disease outbreaks in Africa, 1976 to 2014
S Ng, B J Cowling
Eurosurveillance.2014;[Epub] CrossRef - Early transmission dynamics of Ebola virus disease (EVD), West Africa, March to August 2014
H Nishiura, G Chowell
Eurosurveillance.2014;[Epub] CrossRef - Transmission dynamics and control of Ebola virus disease outbreak in Nigeria, July to September 2014
F O Fasina, A Shittu, D Lazarus, O Tomori, L Simonsen, C Viboud, G Chowell
Eurosurveillance.2014;[Epub] CrossRef - The Road Less Traveled
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