- Corrigendum to “Investigation of Biofilm Formation and its Association with the Molecular and Clinical Characteristics of Methicillin-resistant Staphylococcus aureus” [Volume 4, Issue 5, October 2013, Pages 225–232]
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Jeong-Ok Cha, Jae Il Yoo, Jung Sik Yoo, Hae-Sun Chung, Sun-Hee Park, Hwa Su Kim, Yeong Seon Lee, Gyung Tae Chung
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Osong Public Health Res Perspect. 2014;5(2):116-116. Published online April 30, 2014
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DOI: https://doi.org/10.1016/j.phrp.2014.04.002
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- Investigation of Biofilm Formation and its Association with the Molecular and Clinical Characteristics of Methicillin-resistant Staphylococcus aureus
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Jeong-Ok Cha, Jae Il Yoo, Jung Sik Yoo, Hae-Sun Chung, Sun-Hee Park, Hwa Su Kim, Yeong Seon Lee, Gyung Tae Chung
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Osong Public Health Res Perspect. 2013;4(5):225-232. Published online October 31, 2013
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DOI: https://doi.org/10.1016/j.phrp.2013.09.001
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 Abstract
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- Objectives
To investigate the biofilm-forming related factors against MRSA bloodstream isolates and evaluates their clinical features and treatment outcomes by biofilm production.
Methods
We collected 126 consecutive methicillin-resistant Staphylococcus aureus (MRSA) causing blood stream infections (BSIs) at 10 tertiary hospitals from 2007 to 2009. We investigated biofilm-forming ability using a microtiter plate assay, and molecular characteristics including multilocus sequence typing, staphylococcal cassette chromosome mec and accessory gene regulator types. We compared the clinical characteristics and outcomes of patients infected with biofilm-forming and non-biofilm-forming MRSA isolates.
Results
Of the 126 samples, 86 (68.3%), including 5 strong level (OD570 ≥ 1.0) and 81 weak level (0.2 ≤ OD570 < 1.0), had biofilm-forming capacity. Detection of fibronectinbinding protein in biofilm-forming strains was significantly higher than biofilm non-forming ones (p = 0.001) and three enterotoxin genes (sec-seg-sei) islands had a high frequency regardless of biofilm production. However, biofilm-forming strains were more likely to be multidrug resistant (three or more non-β-lactam antibiotics) than biofilm non-forming ones [79.2% vs. 59.2%, p = 0.015, odds ratio (OR) 2.629, 95% confidence interval (CI) 1.92–5.81]. Clinical features of patients with BSIs caused by biofilm-forming MRSA strains were more likely to be hospital onset [77.9% vs. 60.0%, p = 0.024, OR 2.434, 95% CI 1.11–5.33) and more frequently occurred in patients with use of invasive devices [85.7% vs. 61.2%, p = 0.002, OR 3.879, 95% CI 1.61–8.97]. The other clinical features were compared with the clinical outcomes of the two groups and were not significant (p > 0.05).
Conclusion
Biofilm-forming MRSA strains showed higher frequency of fnbB gene than biofilm non-forming ones and more incidence rates on particular genotypes. And, their patient's features were not significantly different between two groups in this study, except for several clinical factors.
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Citations
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R.D. Castro, S.H.S.P. Pedroso, S.H.C. Sandes, G.O. Silva, K.C.M. Luiz, R.S. Dias, R.A.T. Filho, H.C.P. Figueiredo, S.G. Santos, A.C. Nunes, M.R. Souza
Journal of Dairy Science.2020; 103(3): 2098. CrossRef - Investigation of biofilm production and its association with genetic and phenotypic characteristics of OM (osteomyelitis) and non-OM orthopedic Staphylococcus aureus
Shengpeng Yu, Bei Jiang, Chao Jia, Hongri Wu, Jie Shen, Xiaomei Hu, Zhao Xie
Annals of Clinical Microbiology and Antimicrobials.2020;[Epub] CrossRef - Busting biofilms: free-living amoebae disrupt preformed methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium bovis biofilms
Kevin H. Martin, Grace I. Borlee, William H. Wheat, Mary Jackson, Bradley R. Borlee
Microbiology
.2020; 166(8): 695. CrossRef - Biofilm formation and molecular characterization of methicillin-resistant Staphylococcus aureus strains isolated from the patients, personnel, air and environment of ICUs
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Gene Reports.2020; 20: 100736. CrossRef - Characteristics of Clinically Significant Invasive Staphylococcus aureus Infections in a Tertiary Care Centre
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Sara H. Mohamed, Maram M.S. Elshahed, Yasmine M. Saied, Mahmoud S.M. Mohamed, Gamal H. Osman
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Frontiers in Microbiology.2019;[Epub] CrossRef - Biofilm formation byStaphylococcus aureusclinical isolates correlates with the infection type
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Clinical Microbiology Reviews.2018;[Epub] CrossRef - Fighting biofilms with lantibiotics and other groups of bacteriocins
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Journal of Food Science.2017; 82(10): 2364. CrossRef - MRSA decolonization failure—are biofilms the missing link?
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Critical Reviews in Microbiology.2017; 43(5): 602. CrossRef - Chlorhexidine whole-body washing of patients reduces methicillin-resistant Staphylococcus aureus and has a direct effect on the distribution of the ST5-MRSA-II (New York/Japan) clone
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Journal of Medical Microbiology.2017; 66(6): 721. CrossRef - Bovine origin Staphylococcus aureus: A new zoonotic agent?
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Acta Biomaterialia.2017; 57: 95. CrossRef - Emerging technologies for long-term antimicrobial device coatings: advantages and limitations
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Experimental Biology and Medicine.2017; 242(8): 788. CrossRef - Methicillin-resistant food-related Staphylococcus aureus: a review of current knowledge and biofilm formation for future studies and applications
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Research in Microbiology.2017; 168(1): 1. CrossRef - Biofilm formation of Brazilian meticillin-resistant Staphylococcus aureus strains: prevalence of biofilm determinants and clonal profiles
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