Figure 1Hospital stay.
Figure 2Total bilirubin concentration (mg/dL) expressed as a mean value, over time. The serum concentration of bilirubin expressed as a mean value for the groups was statistically significantly reduced at 72 hours in the Bilinaster and Phototherapy group compared with the Phototherapy treatment group p = 0.001.
Figure 3Direct bilirubin concentration (mg/dL) in the serum expressed as a mean value, over time.
Table 1Baseline characteristics.
|
Group |
Mean |
SD |
p
|
Age (d) |
Control |
8.12 |
5.85 |
0.277 |
Intervention |
7.21 |
4.19 |
Total |
7.67 |
5.09 |
|
Birth weight (g) |
Control |
2,996.40 |
492.49 |
0.026 |
Intervention |
3,162.67 |
409.99 |
Total |
3,079.53 |
459.24 |
|
Age at onset of jaundice (d) |
Control |
4.16 |
2.35 |
0.474 |
Intervention |
3.85 |
2.85 |
Total |
4.01 |
2.61 |
|
Total bilirubin concentration at admission (mg/dL) |
Control |
17.77 |
4.82 |
0.367 |
Intervention |
18.41 |
3.80 |
Total |
18.09 |
4.34 |
|
Direct bilirubin concentration at admission (mg/dL) |
Control |
0.57 |
0.27 |
0.041 |
Intervention |
0.65 |
0.19 |
Total |
0.61 |
0.23 |
Table 2Reduction of bilirubin serum concentration following treatment.
|
Time (h) |
Group |
Mean |
SD |
p
|
Reduced total bilirubin (mg/dL) |
24 |
Control |
3.2280 |
3.17071 |
> 0.05 |
Intervention |
2.9453 |
1.54494 |
|
48 |
Control |
5.8153 |
3.34932 |
< 0.001 |
Intervention |
6.7446 |
2.25584 |
|
72 |
Control |
8.6176 |
4.00613 |
< 0.001 |
Intervention |
11.0459 |
3.25496 |
|
96 |
Control |
12.7471 |
6.23840 |
> 0.05 |
Intervention |
13.0571 |
2.84479 |
|
Reduced direct bilirubin (mg/dL) |
24 |
Control |
0.0720 |
0.17286 |
> 0.05 |
Intervention |
0.1147 |
0.17606 |
|
48 |
Control |
0.1139 |
0.16641 |
> 0.05 |
Intervention |
0.1865 |
0.17067 |
|
72 |
Control |
0.1431 |
0.23260 |
< 0.001 |
Intervention |
0.2378 |
0.18462 |
|
96 |
Control |
0.2706 |
0.28453 |
< 0.001 |
Intervention |
0.2714 |
0.13801 |