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PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS. pISSN: 2210-9099. eISSN: 2233-6052
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Original Article

Instability of Plasma and Serum Progastrin-Releasing Peptide During Repeated Freezing and Thawing

Osong Public Health and Research Perspectives 2016;7(6):351-355.
Published online: November 16, 2016

aNational Biobank of Korea, Center for Genome Sciences, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongju, Korea

bDepartment of Laboratory Medicine, Pusan National University School of Medicine, Busan, Korea

∗Corresponding author. dr.shineyoung@gmail.com
• Received: July 5, 2016   • Accepted: November 10, 2016

Copyright © 2016 Korea Centers for Disease Control and Prevention. Published by Elsevier Korea LLC.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Citations

Citations to this article as recorded by  Crossref logo
  • Effect of Repeated Freeze–Thaw Cycles on Influenza Virus Antibodies
    Alessandro Torelli, Elena Gianchecchi, Martina Monti, Pietro Piu, Irene Barneschi, Carolina Bonifazi, Rosa Coluccio, Luisa Ganfini, Luciano Michele La Magra, Silvia Marconi, Ginevra Marzucchi, Ramona Pace, Laura Palladino, Bernardo Biagi, Emanuele Montomo
    Vaccines.2021; 9(3): 267.     CrossRef
  • The influence of different blood samples treatment methods on pro-gastrin-releasing peptide
    Huiqin Jiang, Ling Luo, Kang Xiong, Chengwen He, Huaizhou Wang, Yanghua Qin
    Medicine.2019; 98(26): e16130.     CrossRef

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Instability of Plasma and Serum Progastrin-Releasing Peptide During Repeated Freezing and Thawing
Osong Public Health Res Perspect. 2016;7(6):351-355.   Published online December 31, 2016
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Osong Public Health Res Perspect. 2016;7(6):351-355.   Published online December 31, 2016
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Instability of Plasma and Serum Progastrin-Releasing Peptide During Repeated Freezing and Thawing
Image Image
Figure 1 Differences of proGRP concentrations between paired plasma and serum samples (ΔproGRP). proGRP = progastrin-releasing peptide; ΔproGRP = plasma progastrin-releasing peptide concentration–serum progastrin-releasing peptide concentration.
Figure 2 Accuracy of ΔproGRP in discriminating plasma and serum samples that had been exposed to four freeze–thaw cycles, compared with those subjected to one freeze–thaw cycle. ΔproGRP = plasma progastrin-releasing peptide concentration–serum progastrin-releasing peptide concentration.
Instability of Plasma and Serum Progastrin-Releasing Peptide During Repeated Freezing and Thawing
Table 1 Changes of proGRP levels in plasma and serum samples exposed to repeated freeze–thaw cycles.

proGRP = progastrin-releasing peptide; SD = standard deviation.

Percentage change, with a “+” for an increase and a “−” for a decrease relative to baseline (1 cycle).

The p value was calculated using a paired two-tailed t test.

Table 2 Thawing time at 37°C and exposure time at room temperature during repeated freezing and thawing of plasma and serum samples.

Data are presented as mean ±SD.