Division of Enteric Diseases, Korea National Institute of Health, Osong, Korea.
Copyright ©2012, Korea Centers for Disease Control and Prevention
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
MIC (μg/mL) | gyrA amino acid at codon | parC amino acid at codon | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
83 | 87 | 157 | 80 | 81 | 84 | ||||||
Strain no. | CIP | CIP + Reserpine | Nor | Nor + Reserpine | GAC (Asp) | GAC (Asp) | CGT (Arg) | AGC (Ser) | GCC (Ala) | GAA (Glu) | qnr, aac(6’)Ib-cr, qepA type |
EACR01 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR02 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR03 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR04 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR05 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR06 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR07 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | |
EACR09 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR10 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR11 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR12 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR15 | 32 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | |
EACR17 | 32 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR18 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR21 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR22 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR23 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -T-(Val) | |
EACR24 | 32 | <2 | 32 | <2 | -T-(Leu) | – | – | – | C–(Pro) | – | |
EACR25 | 128 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | aac(6’) Ib-cr |
EACR29 | 256 | <2 | 64 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | aac(6’) Ib-cr |
EACR31 | 256 | <2 | 64 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | |
EACR32 | 128 | <2 | 64 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | aac(6’) Ib-cr |
EACR33 | <256 | <2 | 256 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -G-(Gly) | qnrA |
EACR38 | 128 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | – | |
EACR39 | 128 | <2 | 64 | <2 | -T-(Leu) | -G-(Gly) | G-(Gly) | -AG(Gln) | – | – | |
EACR41 | 64 | <2 | 32 | <2 | -T-(Leu) | -G-(Gly) | – | -AG(Gln) | – | -G-(Gly) |
Each value is the average of five replicates.
CIP = ciprofloxacin; NOR =norfloxacin.