- Editorial
- Out of Africa, Into Global Health Security Agenda
- Hae-Wol Cho, Chaeshin Chu
- Osong Public Health Res Perspect. 2014;5(6):313-314. Published online December 31, 2014
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- Original Articles
- Optimal Implementation of Intervention to Control the Self-harm Epidemic
- Byul Nim Kim, M.A. Masud, Yongkuk Kim
- Osong Public Health Res Perspect. 2014;5(6):315-323. Published online December 31, 2014
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Objectives Deliberate self-harm (DSH) of a young person has been a matter of growing concern to parents and policymakers. Prevention and early eradication are the main interventional techniques among which prevention through reducing peer pressure has a major role in reducing the DSH epidemic. Our aim is to develop an optimal control strategy for minimizing the DSH epidemic and to assess...
- Predicting 5-Year Survival Status of Patients with Breast Cancer based on Supervised Wavelet Method
- Maryam Farhadian, Hossein Mahjub, Jalal Poorolajal, Abbas Moghimbeigi, Muharram Mansoorizadeh
- Osong Public Health Res Perspect. 2014;5(6):324-332. Published online December 31, 2014
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Objectives Classification of breast cancer patients into different risk classes is very important in clinical applications. It is estimated that the advent of high-dimensional gene expression data could improve patient classification. In this study, a new method for transforming the high-dimensional gene expression data in a low-dimensional space based on wavelet transform (WT) is presented. Methods The proposed method was applied to three...
- Characterization of Plasmid-Mediated AmpC and Carbapenemases among Iranain Nosocomial Isolates of
Klebsiella pneumoniae Using Phenotyping and Genotyping Methods - Alireza Japoni-Nejad, Ehsanollah Ghaznavi-Rad, Alex van Belkum
- Osong Public Health Res Perspect. 2014;5(6):333-338. Published online December 31, 2014
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Objectives Plasmid-mediated AmpC β-lactamases (PMABLs) and carbapenemases are emerging groups of antimicrobial-resistance determinants. The aims of the study were to evaluate the occurrence of PMABLs and carbapenemases in clinical isolates of Klebsiella pneumoniae and compare the test performance of various phenotypic methods for detection of these enzymes in Iran. Methods A total of 100 K. pneumoniae isolates were collected from clinical specimens obtained...
- Dentofacial and Cranial Changes in Down Syndrome
- Deepika Shukla, Deepika Bablani, Aman Chowdhry, Raveena Thapar, Puneet Gupta, Shashwat Mishra
- Osong Public Health Res Perspect. 2014;5(6):339-344. Published online December 31, 2014
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Objectives This study aimed to determine the prevalence of certain oral characteristics usually associated with Down syndrome and to determine the oral health status of these patients. Methods The cross-sectional study was conducted among patients attending a special education program at Faculty of Dentistry, Jamia Millia Islamia, Delhi, India. The study design consisted of closed-ended questions on demographic characteristics (age, sex, and education...
- Aging-related Changes in Mouse Serum Glycerophospholipid Profiles
- Seungwoo Kim, Hyo-Soon Cheon, Jae-Chun Song, Sang-Moon Yun, Sang Ick Park, Jae-Pil Jeon
- Osong Public Health Res Perspect. 2014;5(6):345-350. Published online December 31, 2014
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Objectives Metabolic dysfunction is a common hallmark of the aging process and aging-related pathogenesis. Blood metabolites have been used as biomarkers for many diseases, including cancers, complex chronic diseases, and neurodegenerative diseases. Methods In order to identify aging-related biomarkers from blood metabolites, we investigated the specific metabolite profiles of mouse sera from 4-month-old and 21-month-old mice by using a combined flow injection analysis–tandem...
- Rapid DNA Extraction from Dried Blood Spots on Filter Paper: Potential Applications in Biobanking
- Eun-Hye Choi, Sang Kwang Lee, Chunhwa Ihm, Young-Hak Sohn
- Osong Public Health Res Perspect. 2014;5(6):351-357. Published online December 31, 2014
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Objectives Dried blood spot (DBS) technology is a microsampling alternative to traditional plasma or serum sampling for pharmaco- or toxicokinetic evaluation. DBS technology has been applied to diagnostic screening in drug discovery, nonclinical, and clinical settings. We have developed an improved elution protocol involving boiling of blood spots dried on Whatman filter paper. Methods The purpose of this study was to compare the...
- Antihematotoxic Role of
Bunium persicum Seed Differential Extracts in Animal Model: Reactive Oxygen Species Might Be a Contributor - Tahir Ali, Kamran Saeed, Muhammad Abdullah, Iram Murtaza
- Osong Public Health Res Perspect. 2014;5(6):358-363. Published online December 31, 2014
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Objectives Humans have been using plants as natural medicines since prehistoric times. Bunium persicum is a rich source of oils with different biological activities such as antioxidative and antimicrobial activities. The aim of this study is to evaluate the antihematotoxic and antioxidative effects of the differential extracts of B. persicum against leukemic blood induced hematotoxicity in an animal model. Methods This study was...
- Diversity of Rotavirus Strain Circulated in Gwangju, Republic of Korea
- Min Ji Kim, Hye Sook Jeong, Seon Gyeong Kim, Se Mi Lee, Sun Hee Kim, Hye-Young Kee, Eun-hye Jo, Hye-jung Park, Dong-Ryong Ha, Eun Sun Kim, Kye-Won Seo, Jae Keun Chung
- Osong Public Health Res Perspect. 2014;5(6):364-369. Published online December 31, 2014
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Objectives The introduction of new rotavirus vaccines into the public sphere makes it necessary to maintain constant surveillance and to heighten public awareness of the appearance of new rotavirus strains. We describe the molecular epidemiology of circulating rotavirus strains after vaccine introduction. Methods We collected a total of 1070 stool samples from children with gastroenteritis from January 2013 to June 2013. The antigenic...
- Composition of Metabolic Syndrome Among Korean Adults in a Lifestyle Modification Intervention
- Nan-He Yoon, Seunghyun Yoo, Hyekyeong Kim
- Osong Public Health Res Perspect. 2014;5(6):370-377. Published online December 31, 2014
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Objectives The aim of this study was to examine the composition of metabolic syndrome (MetS) components among middle-aged and older Koreans. Methods A total of 263 participants (age 40 + years) in a lifestyle modification intervention program who met the MetS definition of National Cholesterol Education Program (NCEP) – Adult Treatment Panel (ATP) III criteria were included in the study. The frequent patterns and clustering...
- Brief Reports
- Ebola Hemorrhagic Fever and the Current State of Vaccine Development
- Joo Eun Hong, Kee-Jong Hong, Woo Young Choi, Won-Ja Lee, Yeon Hwa Choi, Chung-Hyeon Jeong, Kwang-il Cho
- Osong Public Health Res Perspect. 2014;5(6):378-382. Published online December 31, 2014
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Current Ebola virus outbreak in West Africa already reached the total number of 1,323 including 729 deaths by July 31st. the fatality is around 55% in the southeastern area of Guinea, Sierra Leone, Liberia, and Nigeria. The number of patients with Ebola Hemorrhagic Fever (EHF) was continuously increasing even though the any effective therapeutics or vaccines has not been developed...
- Acute Human Cytomegalovirus Infection with Bleeding in Iran
- Behzad Pourhossein, Farhad Yaghmaei, Saber Esmaeili, Omid Banafshi, Shahla Afrasiabian, Mohammad Reza Shirzadi, Mark Schleiss, Ehsan Mostafavi
- Osong Public Health Res Perspect. 2014;5(6):383-386. Published online December 31, 2014
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In December 2011, a 42-year-old male farmer was admitted to a hospital in Sanandaj (Western Iran) with fever and anemia in order to check whether he suffered from some infectious diseases. During the first 3 days after admission, the patient gradually developed progressive oliguria, fever, abdominal pain in the right upper quadrant, leukocytosis with toxic granulation, petechiae and ecchymosis, oral...
