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Volume 3(2); Jun 2012
Articles
Can Stigma Still Distort the Spectrum of a Disease?
Hae-Wol Cho, Chaeshin Chu
Osong Public Health Res Perspect. 2012;3(2):65-67.   Published online June 30, 2012
Effect of Maternal Immune Status on Responsiveness of Bacillus Calmette-Gurin Vaccination in Mouse Neonates
Jong Su Choi, Ryang Yeo Kim, Semi Rho, Fanny Ewann, Nathalie Mielcarek, Man Ki Song, Cecil Czerkinsky, Jae-Ouk Kim
Osong Public Health Res Perspect. 2012;3(2):68-73.   Published online June 30, 2012
Objectives Bacillus Calmette-Guérin (BCG) vaccination has proven to be efficient in immunologically naïve infants; however, it has not been investigated that maternal natural exposure to Mycobacterium and/or BCG vaccine could influence the characteristics of immune responses to BCG in newborns. In this study, we analyzed whether the maternal immune status to M tuberculosis (M tb) can affect neonatal immunity to BCG...
Proteomic Analysis of Cellular and Membrane Proteins in Fluconazole-Resistant Candida glabrata
Jae Il Yoo, Chi Won Choi, Hwa Su Kim, Jung Sik Yoo, Young Hee Jeong, Yeong Seon Lee
Osong Public Health Res Perspect. 2012;3(2):74-78.   Published online June 30, 2012
Objectives Candida glabrata is one of the most common causes of Candida bloodstream infections worldwide. Some isolates of C glabrata may be intermediately resistant to azoles, with some strains developing resistance during therapy or prophylaxis with fluconazole. In this study, we used a proteomic approach to identify differentially expressed proteins between fluconazoleresistant and -susceptible strains. Methods Membrane and cellular proteins were extracted from...
Non-chromatographic Method for the Hepatitis B Virus X Protein Using Elastin-Like Polypeptide Fusion Protein
Soon-Hwan Kwon, Hyeseong Cho
Osong Public Health Res Perspect. 2012;3(2):79-84.   Published online June 30, 2012
Objectives Hepatitis B virus (HBV) is a member of the hepadnavirus family. The HBV genome contains four genes designated as S, C, P, and X. The HBV X (HBx) gene encodes for a 16.5-kDa regulatory protein that enhances HBV replication and exerts multifunctional activities. The aim of this study is to describe the rapid and easy purification of HBx using ELP...
Improvements in the Metabolic Syndrome and Stages of Change for Lifestyle Behaviors in Korean Older Adults
Seunghyun Yoo, Hyekyeong Kim, Han-Ik Cho
Osong Public Health Res Perspect. 2012;3(2):85-93.   Published online June 30, 2012
Objectives This study aims to examine the effectiveness of a 6-month lifestyle modification program on the improvement in metabolic syndrome (MetS) status and in stages of change for lifestyle behaviors associated with MetS among Korean older adults. Methods A lifestyle modification program was developed based on the transtheoretical model. The program consisted of health counseling, education classes, a self-management handbook, newsletters and a...
Improving Service Quality in Long-term Care Hospitals: National Evaluation on Long-term Care Hospitals and Employees Perception of Quality Dimensions
Jinkyung Kim, Woosok Han
Osong Public Health Res Perspect. 2012;3(2):94-99.   Published online June 30, 2012
Objectives To investigate predictors for specific dimensions of service quality perceived by hospital employees in long-term care hospitals. Methods Data collected from a survey of 298 hospital employees in 18 long-term care hospitals were analysed. Multivariate ordinary least squares regression analysis with hospital fixed effects was used to determine the predictors of service quality using respondents’ and organizational characteristics. Results The most significant predictors of...
Epidemiological and Immunological Characteristics at the Time of HIV Diagnosis for HIV/AIDS Cohort Registrants Representative of HIV-Infected Populations in Korea
Jin-Hee Lee, Seung Hyun Kim, Jin-Sook Wang, Kyoung Mi Sung, Sung Soon Kim, Mee-Kyung Kee
Osong Public Health Res Perspect. 2012;3(2):100-106.   Published online June 30, 2012
Objectives The Korea HIV/AIDS cohort was constructed with 18 hospitals that care for HIV-infected individuals in 2006. We compared the epidemiological and immunological characteristics of the cohort registrants with those of the HIVinfected population at the time of HIV diagnosis. Methods This study was conducted on 5717 people living with HIV/AIDS from 1985 to 2009, of which 789 individuals registered with the Korea...
Changes in Human Immunodeficiency Virusrelated Knowledge and Stigmatizing Attitudes among Korean Adolescents from 2006 to 2011
Aeree Sohn, SungBok Park
Osong Public Health Res Perspect. 2012;3(2):107-112.   Published online June 30, 2012
Objectives This study assessed the prevalence and changes of human immunodeficiency virus (HIV) knowledge and stigmatizing attitudes in 2006, 2008, and 2011. Methods Three cross-sectional surveys were conducted in 2006, 2008, and 2011. A cross-sectional sample of high school students in Seoul, South Korea was targeted. A self-administered questionnaire measuring general and transmission and discriminatory attitudes was used. Results Misconceptions about casual contact were widespread,...
Multiplex Real-Time Polymerase Chain Reaction-Based Method for the Rapid Detection of gyrA and parC Mutations in Quinolone-Resistant Escherichia coli and Shigella spp.
Junyoung Kim, Semi Jeon, Hyungjun Kim, Misun Park, Soobok Kim, Seonghan Kim
Osong Public Health Res Perspect. 2012;3(2):113-117.   Published online June 30, 2012
Two real-time polymerase chain reaction assays were developed to detect mutations in codons 83 and 87 in gyrA and in codons 80 and 91 in parC, the main sites that causes quinolone resistance in pathogenic Escherichia coli and Shigella spp. isolates. These assays can be employed as a useful method for controlling infections caused by quinolone-resistant E coli and Shigella...

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Print ISSN: 2210-9099
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