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Original Article
Gender Difference in the Association Between E-Cigarette Use and Depression among US Adults
Baksun Sung
Osong Public Health Res Perspect. 2021;12(1):13-19.   Published online February 23, 2021
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  • 2 Web of Science
  • 4 Crossref
AbstractAbstract PDF

The objective of this study was to determine the association between e-cigarette use and depression and examine how this association is different by gender among US adults.


Data from the 2017 Behavioral Risk Factor Surveillance System and Selected Metropolitan/Micropolitan Area Risk Trends was used, and included 174,351 of 230,875 US adults aged 18 years and older. Data were analyzed using the multivariate logistic regression models.


After adjusting for age, race, education, income, marital status, employment status, smoking status, and physical activity, firstly, “current daily e-cigarette users” (AOR = 2.487, p < 0.001), “current non-daily e-cigarette users” (AOR = 1.623, p < 0.001), and “former e-cigarette users” (AOR = 1.573, p < 0.001) were associated with increased odds of depression compared with “never e-cigarette users.” Secondly, women were associated with increased odds of depression compared with men (AOR = 1.797, p < 0.001). Finally, male “current daily e-cigarette users” (AOR = 1.366, p < 0.01) were associated with increased odds of depression compared with female “never e-cigarette users.”


Thus, even though women tend to be more vulnerable to depression compared with men, e-cigarette use was positively associated with depression among both men and women.


Citations to this article as recorded by  
  • Association between e-cigarette use behaviors and perceived harmfulness of e-cigarettes and anxiety/depression symptoms among Black/African American Adults
    David Adzrago, Kayo Fujimoto, Melissa B. Harrell, Antwan Jones, J. Michael Wilkerson
    Preventive Medicine Reports.2023; 31: 102080.     CrossRef
  • Association between E-Cigarette Use Behaviors and Anxiety/Depression among Black/African American Adults Based on Sexual Identity
    David Adzrago, Melissa B. Harrell, Kayo Fujimoto, Antwan Jones, J. Michael Wilkerson
    International Journal of Environmental Research an.2023; 20(3): 2078.     CrossRef
  • The Association Between Nicotine Dependence and Mental Health in the General Population of Saudi Arabia: A Cross-Sectional Analytical Study
    Danah Abdullah Albarrak, Abdulrahman Bandar Alotaibi, Roaa Faisal Alotaibi, Sara Hussain Alramadhan, Alhanouf Ibrahim Bin Muhanna, Abdulrahman Mohammed Aldehan, Khalid A Bin Abdulrahman
    International Journal of General Medicine.2023; Volume 16: 5801.     CrossRef
  • Use of electronic vaping products and mental health among adolescent high school students in the United States: The moderating effect of sex
    Philip Baiden, Hannah S. Szlyk, Patricia Cavazos-Rehg, Henry K. Onyeaka, JaNiene E. Peoples, Erin Kasson
    Journal of Psychiatric Research.2022; 147: 24.     CrossRef

PHRP : Osong Public Health and Research Perspectives