Osong Public Health and Research Perspectives

Association between lifestyle inflammation score and quality of life according to depressive symptom status: a cross-sectional study in the Republic of Korea: Jaegeun Cho, Eunvin Kang, Young-Joo Won; Received February 10, 2026 Accepted May 5, 2026 Published online June 2, 2026; DOI: https://doi.org/10.24171/j.phrp.2026.0153 [Epub ahead of print]

Objectives
This study examined the association between lifestyle inflammation score (LIS) and health-related quality of life, assessed using the EuroQol-5 Dimensions (EQ-5D) index, among adults in the Republic of Korea. It also evaluated whether depressive symptoms moderated this association.
Methods
Data from the 2024 Community Health Survey were analyzed, and 231,386 adults were included. LIS was calculated by integrating smoking, alcohol consumption, physical activity, and body mass index. The dependent variable, quality of life, was assessed using the EQ-5D index. Depressive symptoms, the moderator variable, were assessed using the Patient Health Questionnaire-9, with a score of ≥10 indicating depressive symptoms. Data were analyzed using complex-sample multivariable linear regression to examine interaction effects according to depressive symptom status, followed by simple-slope analyses.
Results
After adjustment for demographic and health-related variables, LIS was significantly and negatively associated with the EQ-5D index (β=–0.0069, p<0.001), indicating that higher levels of inflammation-related lifestyle behaviors were associated with poorer quality of life. Depressive symptoms significantly moderated the association between LIS and the EQ-5D index (β=–0.01727, p<0.001). Simple-slope analyses showed that the adverse association between LIS and quality of life was stronger among individuals with depressive symptoms (β=–0.02349) than among those without depressive symptoms (β=–0.00621).
Conclusion
Inflammation-related lifestyle behaviors were associated with reduced quality of life, and this negative association was stronger among individuals with depressive symptoms. These findings suggest that considering both lifestyle-related inflammatory burden and depressive symptoms may help explain population-level differences in quality of life.

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Child health problems and social determinants as predictors of postpartum depression: a cross-sectional study using 2023 Indonesia Health Survey data: Tri Wurisastuti, Santi Martini; Received March 10, 2026 Accepted April 28, 2026 Published online May 27, 2026; DOI: https://doi.org/10.24171/j.phrp.2026.0223 [Epub ahead of print]

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The impact of digital literacy on older adults’ self-rated health, depression, and life satisfaction: a cross-sectional study using 2023 National Survey of Older Koreans: Myo-Gyeong Kim, Jeonghae Hwang, Nan-He Yoon; Osong Public Health Res Perspect 2025;16(5):465-475.
Published online September 17, 2025; DOI: https://doi.org/10.24171/j.phrp.2025.0255

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Effectiveness of a cognitive behavioral therapy program in stroke patients in the Republic of Korea: a mixed-methods study: So-Eun Choi, Deok-Ju Kim; Osong Public Health Res Perspect 2024;15(5):461-475.
Published online September 30, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0116

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Associations of type and intensity of social participation with depression, self-rated health, and life satisfaction among community-dwelling older adults in the Republic of Korea: a nationwide cross-sectional study: Myo-Gyeong Kim, Sookja Choi; Osong Public Health Res Perspect 2024;15(5):451-460.
Published online August 21, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0039

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Factors affecting depression and health-related quality of life in the elderly during the COVID-19 pandemic: Deok-Ju Kim; Osong Public Health Res Perspect 2023;14(6):520-529.
Published online November 16, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0166

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Published online August 9, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0110

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