Osong Public Health and Research Perspectives

Bridging innovation and policy: comparative pathways of national vaccine development in low- and middle-income countries: Vahid Marandi; Osong Public Health Res Perspect 2025;16(5):425-436.
Published online September 17, 2025; DOI: https://doi.org/10.24171/j.phrp.2025.0208

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Design and evaluation of a multi-epitope subunit vaccine against human norovirus using an immunoinformatics approach: Zxcy L. Nonog, Edward C. Banico, Ma. Easter V. Sajo, Pablo V. Serrano, Fredmoore L. Orosco; Osong Public Health Res Perspect 2025;16(3):236-251.
Published online April 25, 2025; DOI: https://doi.org/10.24171/j.phrp.2024.0349

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Comparison and consideration of vaccine injury compensation programs in the Republic of Korea, Japan, and Taiwan: Cho Ryok Kang, Young June Choe, Jihyun Moon, Dooyoung Kim, Taemi Kim, Jong-Koo Lee; Osong Public Health Res Perspect 2024;15(6):479-488.
Published online November 12, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0129

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Safety of the bivalent COVID-19 mRNA booster vaccination among persons aged over 18 years in the Republic of Korea: Seok-Kyoung Choi, Seontae Kim, Mijeong Ko, Yeseul Heo, Tae Eun Kim, Yeonkyeong Lee, Juyeon Jang, Eunok Bahng; Osong Public Health Res Perspect 2024;15(6):542-549.
Published online October 29, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0194

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Methodology of comparative studies on the relative effectiveness of COVID-19 vaccines: a systematic review: Erdenetuya Bolormaa, Jiae Shim, Young-Sook Choi, Donghyok Kwon, Young June Choe, Seung-Ah Choe; Osong Public Health Res Perspect 2024;15(5):395-408.
Published online October 15, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0063

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Comparative safety of monovalent and bivalent mRNA COVID-19 booster vaccines in adolescents aged 12 to 17 years in the Republic of Korea: Mijeong Ko, Seontae Kim, Seok-Kyoung Choi, Seung Hwan Shin, Yeon-Kyeng Lee, Yunhyung Kwon; Osong Public Health Res Perspect 2024;15(4):364-374.
Published online July 9, 2024; DOI: https://doi.org/10.24171/j.phrp.2024.0081

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The COVID-19 Vaccine Safety Research Center: a cornerstone for strengthening safety evidence for COVID-19 vaccination in the Republic of Korea: Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Jaehun Jung, Joongyub Lee, Ju-Young Shin, Sun-Young Jung, Byung-Joo Park, Nam-Kyong Choi; Osong Public Health Res Perspect 2024;15(2):97-106.
Published online April 4, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0343

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Psychiatric adverse events associated with the COVID-19 vaccines approved in the Republic of Korea: a systematic review: Seungeun Ryoo, Miyoung Choi, Nam-Kyong Choi, Hyoung-Shik Shin, Jun Hee Woo, Byung-Joo Park, Sanghoon Oh; Osong Public Health Res Perspect 2024;15(2):107-114.
Published online March 28, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0325

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COVID-19 infection among people with disabilities in 2021 prior to the Omicron-dominant period in the Republic of Korea: a cross-sectional study: Seul-Ki Kang, Bryan Inho Kim; Osong Public Health Res Perspect 2024;15(2):150-158.
Published online March 28, 2024; DOI: https://doi.org/10.24171/j.phrp.2023.0194

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Evaluation of COVID-19 vaccine effectiveness in different high-risk facility types during a period of Delta variant dominance in the Republic of Korea: a cross-sectional study: Min Jei Lee, Myung-Jae Hwang, Dong Seob Kim, Seon Kyeong Park, Jihyun Choi, Ji Joo Lee, Jong Mu Kim, Young-Man Kim, Young-Joon Park, Jin Gwack, Sang-Eun Lee; Osong Public Health Res Perspect 2023;14(5):418-426.
Published online October 19, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0188

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JYNNEOS vaccine safety monitoring in the Republic of Korea, 2022: a cross-sectional study: Jaeeun Lee, Seunghyun Lewis Kwon, Jinhee Park, Hyuna Bae, Hyerim Lee, Geun-Yong Kwon; Osong Public Health Res Perspect 2023;14(5):433-438.
Published online October 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0182

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Prevalence and patterns of adverse events following childhood immunization and the responses of mothers in Ile-Ife, South West Nigeria: a facility-based cross-sectional survey: Olorunfemi Akinbode Ogundele, Funmito Omolola Fehintola, Mubarak Salami, Rahmat Usidebhofoh, Mary Aderemi Abaekere; Osong Public Health Res Perspect 2023;14(4):291-299.
Published online July 27, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0071

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Temporal association between the age-specific incidence of Guillain-Barré syndrome and SARS-CoV-2 vaccination in Republic of Korea: a nationwide time-series correlation study: Hyunju Lee, Donghyok Kwon, Seoncheol Park, Seung Ri Park, Darda Chung, Jongmok Ha; Osong Public Health Res Perspect 2023;14(3):224-231.
Published online June 22, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0050

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The incidence and clinical characteristics of myocarditis and pericarditis following mRNA-based COVID-19 vaccination in Republic of Korea adolescents from July 2021 to September 2022: Ju-Young Sim, Seung-Yun Kim, Eun-Kyoung Kim; Osong Public Health Res Perspect 2023;14(2):76-88.
Published online April 18, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0032

Objectives
Age-specific information regarding myocarditis/pericarditis in adolescents following mRNA-based coronavirus disease 2019 (COVID-19) vaccination in Asia remains insufficient. This study investigated the incidence and clinical characteristics of myocarditis/pericarditis in Republic of Korea adolescents after mRNA-based COVID-19 vaccination.
Methods
This retrospective descriptive study utilized patient data from the Korea Immunization Management System. Incidence rates were calculated according to age and sex. Clinical characteristics (symptoms/signs, laboratory values, and imaging results) were compared between mild and severe cases.
Results
Between July 19, 2021 and September 30, 2022, 3,728,224 individuals aged 12 to 19 years received 6,484,165 mRNA-based COVID-19 vaccines, and 173 cases met the case definition for myocarditis/pericarditis: 151 mild (87.3%) and 22 severe (12.7%). The incidence was 3.8-fold higher in males than in females. Troponin I/ troponin T was elevated in 96% of myocarditis cases, demonstrating higher sensitivity than creatine kinase-myocardial band (67.6%) or C-reactive protein (75.2%). ST-segment or Twave on electrography abnormalities were found in 60.3% (85/141). Paroxysmal/sustained atrial/ventricular arrhythmias were more common in severe than in mild cases (45.5% vs. 16.8%, p=0.008). Edema on T2-weighted magnetic imaging occurred in 21.6% (8/37) and 62.5% (5/8) of mild and severe cases, respectively (p=0.03). Abnormal pericardial fluid collection or pericardial inflammation was found in 75.4% of pericarditis cases (49/65).
Conclusion
Myocarditis/pericarditis occurred in rare cases following mRNA-based COVID-19 vaccination. Most cases were mild, but the incidence was higher in adolescent males and after the second dose. As bivalent severe acute respiratory syndrome coronavirus 2 mRNA vaccination started in Republic of Korea in October 2022, the post-vaccination incidence of myocarditis/pericarditis should be closely monitored, considering clinical characteristics.

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A framework for nationwide COVID-19 vaccine safety research in the Republic of Korea: the COVID-19 Vaccine Safety Research Committee: Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi; Osong Public Health Res Perspect 2023;14(1):5-14.
Published online February 28, 2023; DOI: https://doi.org/10.24171/j.phrp.2023.0026

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A Causality Assessment Framework for COVID-19 Vaccines and Adverse Events at the COVID-19 Vaccine Safety Research Center
Seyoung Kim, Jeong Ah Kim, Hyesook Park, Sohee Park, Sanghoon Oh, Seung Eun Jung, Hyoung-Shik Shin, Jong Koo Lee, Hee Chul Han, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi, Dong-Hyun Kim
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Risk of lymphadenopathy from SARS-CoV-2 vaccination in Korea: a self-controlled case series analysis
Mi-Sook Kim, Bongyoung Kim, Jeong Pil Choi, Nam-Kyong Choi, Jung Yeon Heo, Jun Yong Choi, Joongyub Lee, Sang Il Kim
Epidemiology and Health.2023; 45: e2023090. CrossRef

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Adverse events of the Pfizer-BioNTech COVID-19 vaccine in Korean children and adolescents aged 5 to 17 years: Seontae Kim, Yeseul Heo, Soon-Young Seo, Do Sang Lim, Enhi Cho, Yeon-Kyeng Lee; Osong Public Health Res Perspect 2022;13(5):382-390.
Published online October 14, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0233

Abstract
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Presumed population immunity to SARS-CoV-2 in South Korea, April 2022: Eun Jung Jang, Young June Choe, Seung Ah Choe, Yoo-Yeon Kim, Ryu Kyung Kim, Jia Kim, Do Sang Lim, Ju Hee Lee, Seonju Yi, Sangwon Lee, Young-Joon Park; Osong Public Health Res Perspect 2022;13(5):377-381.
Published online October 14, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0209

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India’s efforts to achieve 1.5 billion COVID-19 vaccinations: a narrative review: Kapil Singh, Ashwani Verma, Monisha Lakshminarayan; Osong Public Health Res Perspect 2022;13(5):316-327.
Published online October 14, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0104

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Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea: Seontae Kim, Insob Hwang, Mijeong Ko, Yunhyung Kwon, Yeon-Kyeng Lee; Osong Public Health Res Perspect 2022;13(3):230-237.
Published online June 10, 2022; DOI: https://doi.org/10.24171/j.phrp.2022.0122

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Post vaccination acute kidney injury and other renal complications after COVID-19 and influenza vaccination
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