Skip Navigation
Skip to contents

PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
12 "Safety"
Filter
Filter
Article category
Keywords
Publication year
Authors
Funded articles
Original Article
Comparative safety of monovalent and bivalent mRNA COVID-19 booster vaccines in adolescents aged 12 to 17 years in the Republic of Korea
Mijeong Ko, Seontae Kim, Seok-Kyoung Choi, Seung Hwan Shin, Yeon-Kyeng Lee, Yunhyung Kwon
Osong Public Health Res Perspect. 2024;15(4):364-374.   Published online July 9, 2024
DOI: https://doi.org/10.24171/j.phrp.2024.0081
  • 902 View
  • 53 Download
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Objectives
This study analyzed the safety of coronavirus disease 2019 (COVID-19) bivalent and monovalent booster vaccines, including the frequency of adverse events (AEs) such as myocarditis and pericarditis, in adolescents aged 12 to 17 years in the Republic of Korea. We aimed to share the safety profile of the COVID-19 bivalent vaccine booster doses.
Methods
We analyzed the frequencies of AEs reported to the COVID-19 vaccination management system (CVMS) or self-reported through the text message survey (TMS). Diagnostic eligibility and causality with vaccines were compared using odds ratios (ORs) by vaccine type, and incidence rates per 100,000 person-days were calculated for confirmed cases of myocarditis and pericarditis following monovalent and bivalent booster doses.
Results
In the CVMS, the AE reporting rate (per 100,000 doses) was lower after the bivalent booster (66.5) than after the monovalent booster (264.6). Among the AEs reported for both monovalent and bivalent vaccines 98.3% were non-serious and 1.7% were serious. According to the TMS, both local and systemic AEs were reported less frequently after the bivalent vaccination than after the monovalent vaccination in adolescents aged 12 to 17 years (p<0.001). The incidence rates per 100,000 person-days for confirmed myocarditis/pericarditis following monovalent and bivalent booster doses were 0.03 and 0.05, respectively; this difference was not statistically significant (OR, 1.797; 95% confidence interval, 0.210–15.386).
Conclusion
AEs in 12- to 17-year-olds following the bivalent booster were less frequent than those following the monovalent booster in the Republic of Korea, and no major safety issues were identified. However, the reporting rates for AEs were low.
Special Article
The COVID-19 Vaccine Safety Research Center: a cornerstone for strengthening safety evidence for COVID-19 vaccination in the Republic of Korea
Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Jaehun Jung, Joongyub Lee, Ju-Young Shin, Sun-Young Jung, Byung-Joo Park, Nam-Kyong Choi
Osong Public Health Res Perspect. 2024;15(2):97-106.   Published online April 4, 2024
DOI: https://doi.org/10.24171/j.phrp.2023.0343
  • 2,260 View
  • 96 Download
  • 2 Web of Science
  • 1 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
The COVID-19 Vaccine Safety Research Committee (CoVaSC) was established in November 2021 to address the growing need for independent, in-depth scientific evidence on adverse events (AEs) following coronavirus disease 2019 (COVID-19) vaccination. This initiative was requested by the Korea Disease Control and Prevention Agency and led by the National Academy of Medicine of Korea. In September 2022, the COVID-19 Vaccine Safety Research Center was established, strengthening CoVaSC’s initiatives. The center has conducted various studies on the safety of COVID-19 vaccines. During CoVaSC’s second research year, from September 29, 2022 to July 19, 2023, the center was restructured into 4 departments: Epidemiological Research, Clinical Research, Communication & Education, and International Cooperation & Policy Research. Its main activities include (1) managing CoVaSC and the COVID-19 Vaccine Safety Research Center, (2) surveying domestic and international trends in AE causality investigation, (3) assessing AEs following COVID-19 vaccination, (4) fostering international collaboration and policy research, and (5) organizing regular fora and training sessions for the public and clinicians. Causality assessments have been conducted for 27 diseases, and independent research has been conducted after organizing ad hoc committees comprising both epidemiologists and clinical experts on each AE of interest. The research process included protocol development, data analysis, interpretation of results, and causality assessment. These research outcomes have been shared transparently with the public and healthcare experts through various fora. The COVID-19 Vaccine Safety Research Center plans to continue strengthening and expanding its research activities to provide reliable, high-quality safety information to the public.

Citations

Citations to this article as recorded by  
  • SARS-CoV-2-Vaccine-Related Endocrine Disorders: An Updated Narrative Review
    Avraham Ishay, Kira Oleinikov, Elena Chertok Shacham
    Vaccines.2024; 12(7): 750.     CrossRef
Brief Report
JYNNEOS vaccine safety monitoring in the Republic of Korea, 2022: a cross-sectional study
Jaeeun Lee, Seunghyun Lewis Kwon, Jinhee Park, Hyuna Bae, Hyerim Lee, Geun-Yong Kwon
Osong Public Health Res Perspect. 2023;14(5):433-438.   Published online October 18, 2023
DOI: https://doi.org/10.24171/j.phrp.2023.0182
  • 1,565 View
  • 50 Download
  • 4 Web of Science
  • 3 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Objectives
With the recent global mpox outbreak, the JYNNEOS vaccine (Modified Vaccinia Ankara-Bavarian Nordic) was developed as a third-generation smallpox vaccine and initially favored for mpox immunization. Vaccine-associated side effects contribute to vaccine hesitancy. Consequently, tracking adverse events post-immunization is crucial for safety management. This study used data from the national active vaccine safety surveillance conducted in Korea from August 25 to November 24, 2022 to detect potential safety signals and adverse events. Methods: Data on health conditions following vaccination were gathered from web-based surveys and reported via active surveillance through the Immunization Registry Information System. This follow-up system functioned via a text message link, surveying adverse events and health conditions beginning on the second day post-vaccination. Information about specific adverse events, including both local and systemic reactions, was collected. Results: The study included 86 healthcare workers who had received at least 1 dose of the JYNNEOS vaccine. Among the respondents, 79.1% reported experiencing at least 1 adverse event, with the majority being local reactions at the injection site. The incidence of adverse events was higher following the first dose (67.9%) than after the second dose (34.4%). The most frequently reported adverse event for both doses was mild pain at the injection site. Conclusion: The study provides crucial information on the safety of the JYNNEOS vaccine, demonstrating that most adverse events were manageable and predominantly localized to the injection site. Nonetheless, additional research is needed on the safety of various vaccine administration techniques and the vaccine’s effects on broader demographics.

Citations

Citations to this article as recorded by  
  • Adverse Reactions After Intradermal Vaccination With JYNNEOS for Mpox in Korea
    So Yun Lim, Yu Mi Jung, Yeonjae Kim, Gayeon Kim, Jaehyun Jeon, BumSik Chin, Min-Kyung Kim
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • First Nationwide Mpox Vaccination Program in the Republic of Korea: Implications for an Enhanced Public Health Response
    Seunghyun Lewis Kwon, Minju Song, Wonkyung Lee, Jeeyeon Shin, Su-Yeon Lee, Sang-Gu Yeo, Minjeong Kim, Sanggyun Jeong, Joonku Park, Dongwoo Lee, Sookyoung Lim
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Global perspectives on smallpox vaccine against monkeypox: a comprehensive meta-analysis and systematic review of effectiveness, protection, safety and cross-immunogenicity
    Hao Liu, Wenjing Wang, Yang Zhang, Fuchun Wang, Junyi Duan, Tao Huang, Xiaojie Huang, Tong Zhang
    Emerging Microbes & Infections.2024;[Epub]     CrossRef
Review Article
Points to consider when developing drugs for dry eye syndrome
Suyoung Bae, Hosun Seung, Ho Jung Oh
Osong Public Health Res Perspect. 2023;14(2):70-75.   Published online April 26, 2023
DOI: https://doi.org/10.24171/j.phrp.2023.0031
  • 2,144 View
  • 127 Download
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Changes in both the social environment (e.g., the increased use of electronic media) and the atmospheric environment (e.g., air pollution and dust) have contributed to an increasing incidence of eye disease and an increased need for eye care. Notably, the signs and symptoms of dry eye syndrome can impact the daily quality of life for various age groups, including the elderly, and usually requires active treatment. The symptoms of dry eye syndrome include tear film instability, hyperosmolarity, ocular surface inflammation and damage, and neurosensory abnormalities. As treatments for dry eye are being developed, a standardized guideline is needed to increase the efficiency of drug development and improve the quality of clinical trial data. In this paper, we present general considerations for the pharmaceutical industry and clinical trial investigators designing clinical trials focused on the development of drugs to treat dry eye syndrome.
Special Article
A framework for nationwide COVID-19 vaccine safety research in the Republic of Korea: the COVID-19 Vaccine Safety Research Committee
Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi
Osong Public Health Res Perspect. 2023;14(1):5-14.   Published online February 28, 2023
DOI: https://doi.org/10.24171/j.phrp.2023.0026
  • 3,918 View
  • 169 Download
  • 7 Web of Science
  • 5 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
With the introduction of coronavirus disease 2019 (COVID-19) vaccines, the Korea Disease Control and Prevention Agency (KDCA) commissioned the National Academy of Medicine of Korea to gather experts to independently assess post-vaccination adverse events. Accordingly, the COVID-19 Vaccine Safety Research Committee (CoVaSC) was launched in November 2021 to perform safety studies and establish evidence for policy guidance. The CoVaSC established 3 committees for epidemiology, clinical research, and communication. The CoVaSC mainly utilizes pseudonymized data linking KDCA’s COVID-19 vaccination data and the National Health Insurance Service’s claims data. The CoVaSC’s 5-step research process involves defining the target diseases and organizing ad-hoc committees, developing research protocols, performing analyses, assessing causal relationships, and announcing research findings and utilizing them to guide compensation policies. As of 2022, the CoVaSC completed this research process for 15 adverse events. The CoVaSC launched the COVID-19 Vaccine Safety Research Center in September 2022 and has been reorganized into 4 divisions to promote research including international collaborative studies, long-/short-term follow-up studies, and education programs. Through these enhancements, the CoVaSC will continue to swiftly provide scientific evidence for COVID-19 vaccine research and compensation and may serve as a model for preparing for future epidemics of new diseases.

Citations

Citations to this article as recorded by  
  • Risk of encephalitis and meningitis after COVID-19 vaccination in South Korea: a self-controlled case series analysis
    Ju Hwan Kim, Dongwon Yoon, Hwa Yeon Ko, Kyungyeon Jung, Jun-Sang Sunwoo, Won Chul Shin, Jung-Ick Byun, Ju-Young Shin
    BMC Medicine.2024;[Epub]     CrossRef
  • The COVID-19 Vaccine Safety Research Center: a cornerstone for strengthening safety evidence for COVID-19 vaccination in the Republic of Korea
    Na-Young Jeong, Hyesook Park, Sanghoon Oh, Seung Eun Jung, Dong-Hyun Kim, Hyoung-Shik Shin, Hee Chul Han, Jong-Koo Lee, Jun Hee Woo, Jaehun Jung, Joongyub Lee, Ju-Young Shin, Sun-Young Jung, Byung-Joo Park, Nam-Kyong Choi
    Osong Public Health and Research Perspectives.2024; 15(2): 97.     CrossRef
  • A Causality Assessment Framework for COVID-19 Vaccines and Adverse Events at the COVID-19 Vaccine Safety Research Center
    Seyoung Kim, Jeong Ah Kim, Hyesook Park, Sohee Park, Sanghoon Oh, Seung Eun Jung, Hyoung-Shik Shin, Jong Koo Lee, Hee Chul Han, Jun Hee Woo, Byung-Joo Park, Nam-Kyong Choi, Dong-Hyun Kim
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • To become a more stronger and safer country
    Jong-Koo Lee
    Osong Public Health and Research Perspectives.2023; 14(2): 67.     CrossRef
  • Risk of lymphadenopathy from SARS-CoV-2 vaccination: a self-controlled case series analysis
    Mi-Sook Kim, Bongyoung Kim, Jeong Pil Choi, Nam-Kyong Choi, Jung Yeon Heo, Jun Yong Choi, Joongyub Lee, Sang Il Kim
    Epidemiology and Health.2023; : e2023090.     CrossRef
Brief Reports
Adverse events of the Pfizer-BioNTech COVID-19 vaccine in Korean children and adolescents aged 5 to 17 years
Seontae Kim, Yeseul Heo, Soon-Young Seo, Do Sang Lim, Enhi Cho, Yeon-Kyeng Lee
Osong Public Health Res Perspect. 2022;13(5):382-390.   Published online October 14, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0233
  • 2,987 View
  • 120 Download
  • 1 Web of Science
  • 3 Crossref
AbstractAbstract PDF
Objectives
This study aimed to identify potential safety signals and adverse events following the primary Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccination series among children and adolescents aged 5 to 17 years in the Republic of Korea. Methods: Adverse events reported through the COVID-19 vaccination management system (CVMS, a web-based passive vaccine safety surveillance system) and adverse events and health conditions collected from a text message-based survey were analyzed. Results: A total of 14,786 adverse events among 5 to 17-year-old children and adolescents were reported in the CVMS; 14,334 (96.9%) were non-serious and 452 (3.1%) were serious, including 125 suspected cases of acute cardiovascular injury and 101 suspected cases of anaphylaxis. The overall reporting rate was lower in 5 to 11-year-old children (64.5 per 100,000 doses) than in 12 to 17-year-old adolescents (300.5 per 100,000 doses). The text message survey identified that local and systemic adverse events after either dose were reported less frequently in 5 to 11-year-old children than in 12 to 17-year-old adolescents (p<0.001). The most commonly reported adverse events were pain at the injection site, myalgia, headache, and fatigue/tiredness. Conclusion: The overall results are consistent with the results of controlled trials; serious adverse events were extremely rare among 5 to 17-year-old children and adolescents following Pfizer-BioNTech COVID-19 vaccination. Adverse events were less frequent in children aged 5 to 11 years than in adolescents aged 12 to 17 years.

Citations

Citations to this article as recorded by  
  • The descriptive epidemiology of adverse events following two doses of mRNA COVID-19 vaccination in Curaçao, the Caribbean
    Jonathan Lambo, Sirving Keli, Shaheen Khan Kaplan, Temiloluwa Njideaka-Kevin, Sireesha Bala Arja, Alaa Khedir Omer Altahir, Itunu Olonade, Rohit Kumar
    Infectious Diseases.2024; : 1.     CrossRef
  • Safety monitoring of COVID-19 vaccines: February 26, 2021, To June 4, 2022, Republic of Korea
    Yeon-Kyeng Lee, Yunhyung Kwon, Yesul Heo, Eun Kyoung Kim, Seung Yun Kim, Hoon Cho, Seontae Kim, Mijeong Ko, Dosang Lim, Soon-Young Seo, Enhi Cho
    Clinical and Experimental Pediatrics.2023; 66(10): 415.     CrossRef
  • Effectiveness of the BNT162b2 vaccine in preventing morbidity and mortality associated with COVID-19 in children aged 5 to 11 years: A systematic review and meta-analysis
    Sumayyah Ebrahim, Ntombifuthi Blose, Natasha Gloeck, Ameer Hohlfeld, Yusentha Balakrishna, Rudzani Muloiwa, Andy Gray, Andy Parrish, Karen Cohen, Ruth Lancaster, Tamara Kredo, Julia Robinson
    PLOS Global Public Health.2023; 3(12): e0002676.     CrossRef
Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea
Seontae Kim, Insob Hwang, Mijeong Ko, Yunhyung Kwon, Yeon-Kyeng Lee
Osong Public Health Res Perspect. 2022;13(3):230-237.   Published online June 10, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0122
  • 4,953 View
  • 147 Download
  • 9 Web of Science
  • 10 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Objectives
This study aimed to disseminate information on coronavirus disease 2019 (COVID-19) vaccine safety among adolescents aged 12 to 17 years in the Republic of Korea. Methods: Two databases were used to assess COVID-19 vaccine safety in adolescents aged 12 to 17 years who completed the primary Pfizer-BioNTech vaccination series. Adverse events reported to the web-based COVID-19 vaccination management system (CVMS) and collected in the text message-based system were analyzed. Results: From March 5, 2021 to February 13, 2022, 12,216 adverse events among 12- to 17-yearolds were reported to the CVMS, of which 97.1% were non-serious adverse events and 2.9% were serious adverse events, including 85 suspected cases of anaphylaxis, 74 suspected cases of myocarditis and/or pericarditis, and 2 deaths. From December 13, 2021 to January 26, 2022, 10,389 adolescents responded to a text message survey, and local/systemic adverse events were more common after dose 2 than after dose 1. The most commonly reported events following either vaccine dose were pain at the injection site, headache, fatigue/tiredness, and myalgia. Conclusion: The overall results are consistent with previous findings; the great majority of adverse events were non-serious, and serious adverse events were rare among adolescents aged 12 to 17 years following Pfizer-BioNTech COVID-19 vaccination.

Citations

Citations to this article as recorded by  
  • Suspected Myocarditis after mRNA COVID-19 Vaccination among South Korean Adolescents
    Mi Jin Kim, Jin Hee Kim, Hyun Ok Jun, Kyung Min Kim, Min Sub Jeung, Jun Sung Park
    Journal of Pediatric Infectious Diseases.2024; 19(02): 075.     CrossRef
  • Characterization of Brighton Collaboration criteria for myocarditis and pericarditis following COVID-19 vaccine in Korean adolescents
    Jue Seong Lee, HyoSug Choi, Seung Hwan Shin, Myung-Jae Hwang, Sara Na, Jong Hee Kim, Sangshin Park, Yoonsun Yoon, Hyun Mi Kang, Bin Ahn, Kyoungsan Seo, Young June Choe
    Vaccine.2024; 42(14): 3333.     CrossRef
  • Myopericarditis following COVID-19 vaccination in children: a systematic review and meta-analysis
    Ashiley Annushri Thenpandiyan, Ryan Ruiyang Ling, Robert Grignani, Megan Ruien Ling, Arthena Anushka Thenpandiyan, Bee Choo Tai, Jyoti Somani, Kollengode Ramanathan, Swee Chye Quek
    Singapore Medical Journal.2024;[Epub]     CrossRef
  • Comparative safety of monovalent and bivalent mRNA COVID-19 booster vaccines in adolescents aged 12 to 17 years in the Republic of Korea
    Mijeong Ko, Seontae Kim, Seok-Kyoung Choi, Seung Hwan Shin, Yeon-Kyeng Lee, Yunhyung Kwon
    Osong Public Health and Research Perspectives.2024; 15(4): 364.     CrossRef
  • Association of new onset seizure and COVID‐19 vaccines and long‐term follow‐up: A systematic review and meta‐analysis
    Ali Rafati, Melika Jameie, Mobina Amanollahi, Yeganeh Pasebani, Nastaran Salimi, Mohammad Hosein Feyz Kazemi, Mana Jameie, Mohammad Yazdan Pasebani, Delaram Sakhaei, Fateme Feizollahi, Churl‐Su Kwon
    Epilepsia.2024;[Epub]     CrossRef
  • Immunogenicity, effectiveness, and safety of COVID-19 vaccines among children and adolescents aged 2–18 years: an updated systematic review and meta-analysis
    Peng Gao, Liang-Yu Kang, Jue Liu, Min Liu
    World Journal of Pediatrics.2023; 19(11): 1041.     CrossRef
  • Incidence of myopericarditis after mRNA COVID-19 vaccination: A meta-analysis with focus on adolescents aged 12–17 years
    Bao-Qiang Guo, Hong-Bin Li, Li-Qiang Yang
    Vaccine.2023; 41(28): 4067.     CrossRef
  • Safety monitoring of COVID-19 vaccines: February 26, 2021, To June 4, 2022, Republic of Korea
    Yeon-Kyeng Lee, Yunhyung Kwon, Yesul Heo, Eun Kyoung Kim, Seung Yun Kim, Hoon Cho, Seontae Kim, Mijeong Ko, Dosang Lim, Soon-Young Seo, Enhi Cho
    Clinical and Experimental Pediatrics.2023; 66(10): 415.     CrossRef
  • Risk of Coronavirus Disease 2019 Messenger RNA Vaccination-Associated Myocarditis and Pericarditis – A Systematic Review of Population-Based Data
    Yen-Ching Lin, Chia-Hsuin Chang, Wei-Ju Su, Chin-Hui Yang, Jann-Tay Wang
    Risk Management and Healthcare Policy.2023; Volume 16: 2085.     CrossRef
  • COVID-19 Vaccination in Korea: Past, Present, and the Way Forward
    Eliel Nham, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
COVID-19 vaccine safety monitoring in Republic of Korea from February 26, 2021 to October 31, 2021
Insob Hwang, Kyeongeun Park, Tae Eun Kim, Yunhyung Kwon, Yeon-Kyeng Lee
Osong Public Health Res Perspect. 2021;12(6):396-402.   Published online December 21, 2021
DOI: https://doi.org/10.24171/j.phrp.2021.0310
  • 8,134 View
  • 201 Download
  • 13 Web of Science
  • 12 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDFSupplementary Material
Objectives
This study aimed to present data on reported adverse events following coronavirus disease 2019 (COVID-19) vaccination in Republic of Korea from February 26 to October 31, 2021, and to determine whether any significant patterns emerged from an analysis of the characteristics of suspected adverse event cases for each type of vaccine.
Methods
Adverse events following COVID-19 vaccination reported by medical doctors and forensic pathologists were analyzed. Cases of suspected anaphylaxis were classified using the Brighton Collaboration definition.
Results
By October 31, 2021, a total of 353,535 (0.45%) adverse events were reported after 78,416,802 COVID-19 vaccine doses. Of the adverse events, 96.4% were non-serious and 3.6% were serious. The most frequently reported adverse events were headache, myalgia, and dizziness. Of the 835 reported deaths after COVID-19 vaccination, 2 vaccine-related deaths were confirmed. Suspected anaphylaxis was confirmed in 454 cases using the Brighton Collaboration definition.
Conclusion
The commonly reported symptoms were similar to those described in clinical trials. Most reported adverse events were non-serious, and the reporting rate of adverse events following COVID-19 vaccination was higher in women than in men (581 vs. 315 per 100,000 vaccinations). Confirmed anaphylaxis was reported in 5.8 cases per 1,000,000 vaccinations.

Citations

Citations to this article as recorded by  
  • Anaphylaxis post-COVID-19 vaccinations in Singapore
    Li Fung Peck, Wang Woon Poh, Adena Theen Lim, Sally Bee Leng Soh, Mun Yee Tham, Belinda Pei Qin Foo, Amelia Jing Jing Ng, Patricia Suet Ling Ng, Pei San Ang, Cheng Leng Chan, Dorothy Su Lin Toh, Edmund Jon Deoon Lee, Amelia Santosa, Bernard Yu-Hor Thong,
    Singapore Medical Journal.2024;[Epub]     CrossRef
  • A Nationwide Survey of mRNA COVID-19 Vaccinee’s Experiences on Adverse Events and Its Associated Factors
    Dongwon Yoon, Ha-Lim Jeon, Yunha Noh, Young June Choe, Seung-Ah Choe, Jaehun Jung, Ju-Young Shin
    Journal of Korean Medical Science.2023;[Epub]     CrossRef
  • Temporal association between the age-specific incidence of Guillain-Barré syndrome and SARS-CoV-2 vaccination in Republic of Korea: a nationwide time-series correlation study
    Hyunju Lee, Donghyok Kwon, Seoncheol Park, Seung Ri Park, Darda Chung, Jongmok Ha
    Osong Public Health and Research Perspectives.2023; 14(3): 224.     CrossRef
  • Safety monitoring of COVID-19 vaccines: February 26, 2021, To June 4, 2022, Republic of Korea
    Yeon-Kyeng Lee, Yunhyung Kwon, Yesul Heo, Eun Kyoung Kim, Seung Yun Kim, Hoon Cho, Seontae Kim, Mijeong Ko, Dosang Lim, Soon-Young Seo, Enhi Cho
    Clinical and Experimental Pediatrics.2023; 66(10): 415.     CrossRef
  • Allergic Reactions to COVID-19 Vaccines: Risk Factors, Frequency, Mechanisms and Management
    Nicoletta Luxi, Alexia Giovanazzi, Alessandra Arcolaci, Patrizia Bonadonna, Maria Angiola Crivellaro, Paola Maria Cutroneo, Carmen Ferrajolo, Fabiana Furci, Lucia Guidolin, Ugo Moretti, Elisa Olivieri, Giuliana Petrelli, Giovanna Zanoni, Gianenrico Senna,
    BioDrugs.2022; 36(4): 443.     CrossRef
  • Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea
    Seontae Kim, Insob Hwang, Mijeong Ko, Yunhyung Kwon, Yeon-Kyeng Lee
    Osong Public Health and Research Perspectives.2022; 13(3): 230.     CrossRef
  • Incidence and Characteristics of Adverse Events after COVID-19 Vaccination in a Population-Based Programme
    Laura Bonzano, Olivera Djuric, Pamela Mancuso, Lidia Fares, Raffaele Brancaccio, Marta Ottone, Eufemia Bisaccia, Massimo Vicentini, Alessia Cocconcelli, Alfonso Motolese, Rostyslav Boyko, Paolo Giorgi Rossi, Alberico Motolese
    Vaccines.2022; 10(7): 1111.     CrossRef
  • Global Predictors of COVID-19 Vaccine Hesitancy: A Systematic Review
    Carla Pires
    Vaccines.2022; 10(8): 1349.     CrossRef
  • Anaphylaxis and Related Events Following COVID‐19 Vaccination: A Systematic Review
    Pradipta Paul, Emmad Janjua, Mai AlSubaie, Vinutha Ramadorai, Beshr Mushannen, Ahamed Lazim Vattoth, Wafa Khan, Khalifa Bshesh, Areej Nauman, Ibrahim Mohammed, Imane Bouhali, Mohammed Khalid, Dalia Zakaria
    The Journal of Clinical Pharmacology.2022; 62(11): 1335.     CrossRef
  • Adverse events of the Pfizer-BioNTech COVID-19 vaccine in Korean children and adolescents aged 5 to 17 years
    Seontae Kim, Yeseul Heo, Soon-Young Seo, Do Sang Lim, Enhi Cho, Yeon-Kyeng Lee
    Osong Public Health and Research Perspectives.2022; 13(5): 382.     CrossRef
  • COVID-19 Vaccination in Korea: Past, Present, and the Way Forward
    Eliel Nham, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim
    Journal of Korean Medical Science.2022;[Epub]     CrossRef
  • Self-reported adverse events after 2 doses of COVID-19 vaccine in Korea
    Yunhyung Kwon, Insob Hwang, Mijeong Ko, Hyungjun Kim, Seontae Kim, Soon-Young Seo, Enhi Cho, Yeon-Kyeng Lee
    Epidemiology and Health.2022; 45: e2023006.     CrossRef
COVID-19 vaccine safety monitoring in the Republic of Korea: February 26, 2021 to April 30, 2021
Hyun-kyung Oh, Eun Kyeong Kim, Insob Hwang, Tae Eun Kim, Yeon-kyeong Lee, Eunju Lee, Yeon-Kyeng Lee
Osong Public Health Res Perspect. 2021;12(4):264-268.   Published online August 13, 2021
DOI: https://doi.org/10.24171/j.phrp.2021.0157
  • 6,587 View
  • 150 Download
  • 7 Web of Science
  • 6 Crossref
AbstractAbstract PDF
Objectives
On February 26, 2021, coronavirus disease 2019 (COVID-19) vaccination was started for high-priority groups based on the recommendation of the Advisory Committee on Immunization Practices with 2 available COVID-19 vaccines (AstraZeneca and Pfizer-BioNTech) in Korea. This report provides a summary of adverse events following COVID-19 vaccination as of April 30, 2021.
Methods
Adverse events following immunization are notifiable by medical doctors to the Korea Immunization Management System (KIMS) under the national surveillance system. We analyzed all adverse events reports following COVID-19 vaccination to the KIMS from February 26 to April 30, 2021.
Results
In total, 16,196 adverse events following 3,586,814 administered doses of COVID-19 vaccines were reported in approximately 2 months (February 26 to April 30, 2021). Of these, 15,658 (96.7%) were non-serious adverse events, and 538 (3.3%) were serious adverse events, including 73 (0.5%) deaths. The majority of adverse events (n=13,063, 80.7%) were observed in women, and the most frequently reported adverse events were myalgia (52.2%), fever (44.9%), and headache (34.9%). Of the 73 deaths following the COVID-19 vaccination, none were related to the vaccines.
Conclusion
By April 30, 3.6 million doses of the COVID 19 vaccine had been given in Korea, and the overwhelming majority of reports were for non-serious events. The Korea Disease Control and Prevention Agency continues to monitor the safety of COVID-19 vaccination.

Citations

Citations to this article as recorded by  
  • A prospective cohort study protocol: monitoring and surveillance of adverse events following heterologous booster doses of Oxford AstraZeneca COVID-19 vaccine in previous recipients of two doses of Sinopharm or Sputnik V vaccines in Iran
    Shahin Soltani, Behzad Karami Matin, Mohammad Mehdi Gouya, Sayed Mohsen Zahraei, Ghobad Moradi, Omid Chehri, Moslem Soofi, Mehdi Moradinazar, Fatemeh Khosravi Shadmani, Mahsa Kalantari, Hamidreza Khajeha, Mohammad Hassan Emamian, Farid Najafi
    BMC Public Health.2023;[Epub]     CrossRef
  • Herpes Zoster Reactivation After mRNA and Adenovirus-Vectored Coronavirus Disease 2019 Vaccination: Analysis of National Health Insurance Database
    Jin Gu Yoon, Young-Eun Kim, Min Joo Choi, Won Suk Choi, Yu Bin Seo, Jaehun Jung, Hak-Jun Hyun, Hye Seong, Eliel Nham, Ji Yun Noh, Joon Young Song, Woo Joo Kim, Dong Wook Kim, Hee Jin Cheong
    The Journal of Infectious Diseases.2023; 228(10): 1326.     CrossRef
  • Safety and effectiveness of BNT162b2 mRNA Covid-19 vaccine in adolescents
    Young June Choe, Seonju Yi, Insob Hwang, Jia Kim, Young-Joon Park, Eunhee Cho, Myoungyoun Jo, Hyunju Lee, Eun Hwa Choi
    Vaccine.2022; 40(5): 691.     CrossRef
  • Direct and Indirect Associations of Media Use With COVID-19 Vaccine Hesitancy in South Korea: Cross-sectional Web-Based Survey
    Minjung Lee, Myoungsoon You
    Journal of Medical Internet Research.2022; 24(1): e32329.     CrossRef
  • Self-Reported COVID-19 Vaccines’ Side Effects among Patients Treated with Biological Therapies in Saudi Arabia: A Multicenter Cross-Sectional Study
    Lama T AlMutairi, Wesal Y Alalayet, Sondus I Ata, Khalidah A Alenzi, Yazed AlRuthia
    Vaccines.2022; 10(6): 977.     CrossRef
  • COVID-19 vaccine safety monitoring in Republic of Korea from February 26, 2021 to October 31, 2021
    Insob Hwang, Kyeongeun Park, Tae Eun Kim, Yunhyung Kwon, Yeon-Kyeng Lee
    Osong Public Health and Research Perspectives.2021; 12(6): 396.     CrossRef
Original Articles
Perception and Practice of Road Safety among Medical Students, Mansoura, Egypt
Randah Helal, Ghada El-Khawaga, Abdel-Hady El-Gilany
Osong Public Health Res Perspect. 2018;9(1):25-31.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2018.9.1.05
  • 5,747 View
  • 68 Download
  • 7 Crossref
AbstractAbstract PDF
Objectives

To assess the knowledge and attitude of medical students towards road safety and to determine their driving behavior and its relation to different related factors.

Methods

This cross-sectional study involved 480 medical students at Mansoura University, Egypt. A self-administered questionnaire was used to collect student personal data, knowledge about road safety, attitude towards road safety, and driving practices.

Results

More than 40% of students experienced an injury in the previous year, mainly as a pedestrian (56%), and 15.2% practiced driving, although only 9.6% had a driving licence. Most of the students had correct road safety knowledge except for awareness that the safe time to read maps is when your vehicle is parked (44%), one should drive in the left lane (29.6%), and one should overtake from the right-hand lane only (25.8%). The majority of the students reported that road traffic injuries can be prevented (89.2%). The mean score of the driving practices of the students ranged from 0.66±1.04 to 2.44±6.28 and rural residents showed significantly higher score regarding errors and lapses.

Conclusion

Good road safety knowledge and a favorable, low risk attitude, did not translate into improved road traffic behavior and this highlights the importance of stricter implementation of the existing rules and including road safety in medical education programs.

Citations

Citations to this article as recorded by  
  • Investigating medical student's attitudes about road accident risks: A cross‐sectional study
    Fariba Shahraki‐Sanavi, Seyed Mohammad Nasiraldin Tabatabaei
    Health Science Reports.2024;[Epub]     CrossRef
  • Risk Factors Related to Road Traffic Accidents in Phuket Province, Southern Thailand: a Confirmatory Factor Analysis
    Jinda Kongcharoen, Nutthajit Onmek, Seppo Karrila, Jariya Seksan
    Transactions on Transport Sciences.2022; 13(1): 17.     CrossRef
  • Effect of Educational Intervention on Road Safety Awareness and Practice among Medical Students in Chennai-A Cross-Sectional Study
    Swetha NB, Sujitha P, Ashni Bhandari
    National Journal of Community Medicine.2022; 12(10): 325.     CrossRef
  • Factors associated and knowledge on road traffic accidents, rules among private university students in Chengalpattu district, Tamil Nadu, India – A cross-sectional study
    G. Vijayakrishnan, P. Priyadharshini, Balaji Ramraj, V. V. Anantharaman
    Journal of Education and Health Promotion.2022; 11(1): 148.     CrossRef
  • A STUDY ON BASIC KNOWLEDGE AND PRACTICES FOR ROAD TRAFFIC SAFETY MEASURES AMONG UNDERGRADUATE MEDICAL STUDENTS OF UTTAR PRADESH
    SOM NATH, SANDEEP KUMAR, KAMRAN JAVED NAQUVI, MANJUSHA NATH
    Asian Journal of Pharmaceutical and Clinical Resea.2022; : 110.     CrossRef
  • A cross-sectional study to assess the knowledge, attitude, and practices towards road traffic safety regulations among college going students of himalayan region, Uttarakhand, India
    Swati Sharma, Neha Sharma, Shaili Vyas, Jayanti Semwal
    Journal of Public Health and Primary Care.2020; 1(1): 30.     CrossRef
  • A study on awareness of road traffic accidents and their basic management among medical students of government medical college, Maharashtra, India
    Abhay Srivastava, Shruti Gaikwad, Pallavi Pagdal, Sudip Bhattacharya
    CHRISMED Journal of Health and Research.2019; 6(4): 216.     CrossRef
Development of a Food Safety and Nutrition Education Program for Adolescents by Applying Social Cognitive Theory
Jounghee Lee, Soyeon Jeong, Gyeongah Ko, Hyunshin Park, Youngsook Ko
Osong Public Health Res Perspect. 2016;7(4):248-260.   Published online August 31, 2016
DOI: https://doi.org/10.1016/j.phrp.2016.05.005
  • 3,750 View
  • 22 Download
  • 12 Crossref
AbstractAbstract PDF
Objectives
The purpose of this study was to develop an educational model regarding food safety and nutrition. In particular, we aimed to develop educational materials, such as middle- and high-school textbooks, a teacher’s guidebook, and school posters, by applying social cognitive theory.
Methods
To develop a food safety and nutrition education program, we took into account diverse factors influencing an individual’s behavior, such as personal, behavioral, and environmental factors, based on social cognitive theory. We also conducted a pilot study of the educational materials targeting middle-school students (n = 26), high-school students (n = 24), and dietitians (n = 13) regarding comprehension level, content, design, and quality by employing the 5-point Likert scale in May 2016.
Results
The food safety and nutrition education program covered six themes: (1) caffeine; (2) food additives; (3) foodborne illness; (4) nutrition and meal planning; (5) obesity and eating disorders; and (6) nutrition labeling. Each class activity was created to improve self-efficacy by setting one’s own goal and to increase self-control by monitoring one’s dietary intake. We also considered environmental factors by creating school posters and leaflets to educate teachers and parents. The overall evaluation score for the textbook was 4.0 points among middle- and high-school students, and 4.5 points among dietitians.
Conclusion
This study provides a useful program model that could serve as a guide to develop educational materials for nutrition-related subjects in the curriculum. This program model was created to increase awareness of nutrition problems and self-efficacy. This program also helped to improve nutrition management skills and to promote a healthy eating environment in middle- and high-school students.

Citations

Citations to this article as recorded by  
  • Toward Sustainable Diets—Interventions and Perceptions Among Adolescents: A Scoping Review
    Adeline R Lanham, Jolieke C van der Pols
    Nutrition Reviews.2024;[Epub]     CrossRef
  • Chinese families' knowledge, attitudes, and practices regarding seizure management for children with epilepsy: a mixed-methods study
    Cui Cui, Shuangzi Li, Wenjin Chen, Hengyu Zhou, Xianlan Zheng
    Frontiers in Public Health.2023;[Epub]     CrossRef
  • Effect of a Health-Related Education Program on Food-Related Behaviors of Vulnerable Women in Zanjan: A Pilot Randomized Clinical Trial
    Jalal Hejazi, Sahar Nazari Darab Khani, Mohammad Masoud Vakili, Majid Aminzare
    Journal of Human Environment and Health Promotion.2023; 9(3): 146.     CrossRef
  • Analyzing consumer behaviour towards food and nutrition labeling: A comprehensive review
    K.M. Priya, Sivakumar Alur
    Heliyon.2023; 9(9): e19401.     CrossRef
  • The effect of a nutrition program based on the Health Behavior Interaction Model on primary school students’ nutritional attitudes and behaviors
    Ayşe Burcu Başçı, Oya Nuran Emiroğlu, Bilge Kalanlar
    Journal of Public Health.2023;[Epub]     CrossRef
  • Evaluating the Consistency Between Conceptual Frameworks and Factors Influencing the Safe Behavior of Iranian Workers in the Petrochemical Industry: Mixed Methods Study
    Azita Zahiri Harsini, Philip Bohle, Lynda R Matthews, Fazlollah Ghofranipour, Hormoz Sanaeinasab, Farkhondeh Amin Shokravi, Krishan Prasad
    JMIR Public Health and Surveillance.2021; 7(5): e22851.     CrossRef
  • Critical Consciousness of Food Systems as a Potential Lifestyle Intervention on Health Issues
    Sothy Eng, Carli Donoghue, Tricia Khun, Whitney Szmodis
    American Journal of Lifestyle Medicine.2020; 14(3): 258.     CrossRef
  • Development, Implementation, and Process Evaluation of a Theory-Based Nutrition Education Programme for Adults Living With HIV in Abeokuta, Nigeria
    Temitope K. Bello, Gerda J. Gericke, Una E. MacIntyre
    Frontiers in Public Health.2019;[Epub]     CrossRef
  • What matters for higher education success of private educational institutions? Senior students’ perceptions in Malaysia
    Jayaraman Krishnaswamy, Zarif Hossain, Mohan Kumar Kavigtha, Annamalai Nagaletchimee
    Journal of Applied Research in Higher Education.2019; 11(3): 616.     CrossRef
  • Augmented reality of traditional food for nutrition education
    Cica Yulia, H Hasbullah, E.E. Nikmawati, S.R. Mubaroq, Cep Ubad Abdullah, Isma Widiaty, Ade Gafar Abdullah, Asep Bayu Dani Nandiyanto
    MATEC Web of Conferences.2018; 197: 16001.     CrossRef
  • Decreasing the use of edible oils in China using WeChat and theories of behavior change: study protocol for a randomized controlled trial
    Rui Zhu, Xianglong Xu, Yong Zhao, Manoj Sharma, Zumin Shi
    Trials.2018;[Epub]     CrossRef
  • Chemicals as additives in food processing -a review
    KUMARESAN D, NITHYA SERMUGAPANDIAN, HEMASHREE S, RUBINI K R
    International Journal of Pharma and Bio Science.2017;[Epub]     CrossRef
Impact of Community-Based Approach as Policy Tool: World Health Organization-Designated Safe Communities of Korea and Health Action Zones of the United Kingdom
Changhyun Kang, Jihyung Shin, Bob Matthews
Osong Public Health Res Perspect. 2016;7(1):36-42.   Published online February 28, 2016
DOI: https://doi.org/10.1016/j.phrp.2015.10.005
  • 3,275 View
  • 22 Download
  • 2 Crossref
AbstractAbstract PDF
Objectives
The aim of this study is to ascertain and identify the effectiveness of area-based initiatives as a policy tool mediated by societal and individual factors in the five World Health Organization (WHO)-designated Safe Communities of Korea and the Health Action Zones of the United Kingdom (UK).
Methods
The Korean National Hospital discharge in-depth injury survey from the Korea Centers for Disease Control and Prevention and causes of death statistics by the Statistics Korea were used for all analyses. The trend and changes in injury rate and mortality by external causes were compared among the five WHO-designated Safe Communities in Korea.
Results
The injury incident rates decreased at a greater level in the Safe Communities compared with the national average. Similar results were shown for the changes in unintentional injury incident rates. In comparison of changes in mortality rate by external causes between 2005 and 2011, the rate increase in Safe Communities was higher than the national average except for Jeju, where the mortality rate by external causes decreased.
Conclusion
When the Healthy Action Zones of the UK and the WHO Safe Communities of Korea were examined, the outcomes were interpreted differently among the compared index, regions, and time periods. Therefore, qualitative outcomes, such as bringing the residents' attention to the safety of the communities and promoting participation and coordination of stakeholders, should also be considered as important impacts of the community-based initiatives.

Citations

Citations to this article as recorded by  
  • Working in partnership with communities to improve health and research outcomes. Comparisons and commonalities between the UK and South Africa
    Patricia Wilson, Azwihangwisi Helen Mavhandu-Mudzusi
    Primary Health Care Research & Development.2019;[Epub]     CrossRef
  • THE SAFE COMMUNITY CONCEPT – A SUCCESSFUL TOOL FOR INJURY PREVENTION AND SAFETY PROMOTION
    Birutė Strukčinskienė, Sabine Distl, Sigitas Griškonis
    Visuomenės sveikata.2019; 28(7): 41.     CrossRef

PHRP : Osong Public Health and Research Perspectives
TOP