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Evaluation and follow-up of pain, fatigue, and quality of life in COVID-19 patients
Sevda Adar, Petek Şarlak Konya, Ali İzzet Akçin, Ümit Dündar, Neşe Demirtürk
Osong Public Health Res Perspect. 2023;14(1):40-50.   Published online February 1, 2023
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Graphical AbstractGraphical Abstract AbstractAbstract PDF
We evaluated pain, fatigue, anxiety, depression, and quality of life in patients hospitalized for coronavirus disease 2019 (COVID-19) and observed them over a period of 3 months. We also investigated the relationship of these symptoms to age, sex, disease severity, and levels of anxiety and depression. Methods: The study included 100 confirmed COVID-19 patients (i.e., positive on a polymerase chain reaction test) between the ages of 18 and 75 years. Pain (visual analog scale [VAS]), fatigue (fatigue severity scale), anxiety, and depression (hospital anxiety and depression scales) were evaluated on the first day of hospitalization and at 1-month and 3-month follow-ups. The short form-12 questionnaire was used to measure quality of life at the 1-month and 3-month followups. Results: No differences were found in pain, fatigue, anxiety levels, depression levels, and quality of life according to disease severity. High VAS scores at hospital admission were related to continued pain at the 3-month follow-up (odds ratio [OR], 1.067; p<0.001). High VAS (OR, 1.072; p=0.003) and anxiety levels (OR, 1.360; p=0.007) were related to severe fatigue at the 3-month evaluation. Conclusion: Pain, fatigue, anxiety, and depression appear to be long-term sequelae of COVID-19 and can affect quality of life. High VAS and anxiety levels were found to be associated with long-term fatigue.
Impact of fatigue on quality of life among breast cancer patients receiving chemotherapy
Fares Mohammed Saeed Muthanna, Mahmathi Karuppannan, Bassam Abdul Rasool Hassan, Ali Haider Mohammed
Osong Public Health Res Perspect. 2021;12(2):115-125.   Published online April 29, 2021
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  • 6 Citations
AbstractAbstract PDF
Fatigue is the most frequently reported symptom experienced by cancer patients and has a profound effect on their quality of life (QOL). The study aimed to determine the impact of fatigue on QOL among breast cancer patients receiving chemotherapy and to identify the risk factors associated with severe fatigue incidence.
This was an observational prospective study carried out at multiple centers. In total, 172 breast cancer patients were included. The Functional Assessment of Chronic Illness Therapy-Fatigue Questionnaire was used to measure QOL, while the Brief Fatigue Inventory (BFI) was used to assess the severity of fatigue.
The total average mean and standard deviation of QOL were 84.58±18.07 and 4.65±1.14 for BFI scores, respectively. A significant association between fatigue and QOL was found in linear and multiple regression analyses. The relationships between fatigue severity and cancer stage, chemotherapy dose delay, dose reduction, chemotherapy regimen, and ethnicity were determined using binary logistic regression analysis.
The findings of this study are believed to be useful for helping oncologists effectively evaluate, monitor, and treat fatigue related to QOL changes.


Citations to this article as recorded by  
  • Effectiveness of Therapeutic Exercise Models on Cancer-Related Fatigue in Patients With Cancer Undergoing Chemotherapy: A Systematic Review and Network Meta-analysis
    Aida Herranz-Gómez, Ferran Cuenca-Martínez, Luis Suso-Martí, Clovis Varangot-Reille, Miriam Prades-Monfort, Joaquín Calatayud, Jose Casaña
    Archives of Physical Medicine and Rehabilitation.2023;[Epub]     CrossRef
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    Zahid Sarfaraz Khan, Asim Muhammad, Muhammad Ataullah, Syeda Gulrukh Saba Shah, Tehmina Naushin, Hina Mir, Nabiha Naeem, Ziyad Ahmad, Sudhair Abbas Bangash, Irfan Ullah
    Pakistan BioMedical Journal.2022; : 44.     CrossRef
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    Summeira Jabeen Shah, Hajira Ishaq, Hina Hakeem, Saima Shaheen, Sikandar Ali Khan, Sosan Rauf, Hina Mir, Sudhair Abbas Bangash, Muhammad Ali, Irfan Ullah
    Pakistan BioMedical Journal.2022; : 176.     CrossRef
  • Post stroke intervention trial in fatigue (POSITIF): Randomised multicentre feasibility trial
    Gillian Mead, David Gillespie, Mark Barber, Allan House, Steff Lewis, Hannah Ensor, Simiao Wu, Trudie Chalder
    Clinical Rehabilitation.2022; 36(12): 1578.     CrossRef
  • Quality of Life and Its Associated Factors Among Cancer Patients Receiving Chemotherapy at Oncology Hospitals in Vietnam After the Third Wave of the COVID-19 Pandemic
    Hanh TH Nguyen, Khanh Linh Duong, Son T Nguyen, Quy Trinh, Hao TL Hoang, Toan Q Phung, Hsiang-Wen Lin, Huong TL Nguyen
    Cancer Management and Research.2022; Volume 14: 2429.     CrossRef
  • Effects of traditional Chinese medicine exercise therapy on cancer-related fatigue, anxiety and sleep quality in cancer patients
    Lihao Jiang, Ju Ouyang, Xianfeng Du
    Medicine.2021; 100(44): e27681.     CrossRef

PHRP : Osong Public Health and Research Perspectives