Skip Navigation
Skip to contents

PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS
SEARCH
Search

Search

Page Path
HOME > Search
1 "Kyungjin Jeong"
Filter
Filter
Article category
Keywords
Publication year
Authors
Original Article
Autochthonous Lyme Borreliosis in Humans and Ticks in Korea
Shinje Moon, Jin Gwack, Kyu Jam Hwang, Donghyuk Kwon, Suyeon Kim, Yoontae Noh, Jongyul Roh, E-hyun Shin, Kyungjin Jeong, Wonseok Seok, Seung-Ki Youn
Osong Public Health Res Perspect. 2013;4(1):52-56.   Published online February 28, 2013
DOI: https://doi.org/10.1016/j.phrp.2012.12.001
  • 1,954 View
  • 15 Download
  • 16 Citations
AbstractAbstract PDF
Objective: This study aimed at finding epidemiological and clinical features of autochthonous Lyme borreliosis in humans through epidemiological investigations and identifying its vectors and pathogens through analysis of ticks.
Method
Epidemiological investigations, including review of the retrospective medical records and patient interviews, were conducted in two cases that occurred in 2012. To identify the vectors and pathogens, ticks were collected between September 23 and October 6, 2012 from the area where the tick bite in the first patient occurred. The ticks were classified, and polymerase chain reaction (PCR) tests and cultures were performed.
Results
The first patient, a 46-year-old female, visited a forest in Gangwon province, which was 900 m above sea level, where the tick bite occurred. Two weeks after the tick bite, erythema migrans (12 × 6 cm2 in size) appeared on the site of tick bite, along with fever, chill, fatigue, myalgia, and arthralgia on shoulders, knees, and hips. The second patient, a 44-year-old male, visited a mountain in Gangwon province, which was 1200 m above sea level, where a tick bite occurred. One month after the tick bite, erythema migrans appeared at the site of the tick bite, along with fatigue, myalgia, and arthralgia on the right shoulder and temporomandibular joint. Indirect fluorescent antibody testing and Western blotting were carried out in these two cases for diagnosis, and positive findings were obtained. As a result, Lyme borreliosis could be confirmed. To estimate the pathogens and vectors, the ticks were collected. A total of 122 ticks were collected and only two species, Haemaphysalis japonica and Haemaphysalis flava, were identified. PCR and culture were performed on ticks. However, Borrelia burgdo rferi sensu lato was not isolated from any collected ticks.
Conclusions
This study is significant to confirm Lyme borreliosis officially at first by the national surveillance system, although identification of the mites and pathogens failed.

Citations

Citations to this article as recorded by  
  • Surveillance and Molecular Identification of Borrelia Species in Ticks Collected at U.S. Army Garrison Humphreys, Republic of Korea, 2018–2019
    Seung-Ho Lee, Sung-Tae Chong, Heung-Chul Kim, Terry A Klein, Kyungmin Park, Jingyeong Lee, Jeong-Ah Kim, Won-Keun Kim, Jin-Won Song, Sarah Hamer
    Journal of Medical Entomology.2022; 59(1): 363.     CrossRef
  • De novo transcriptome sequencing and comparative profiling of the ovary in partially engorged and fully engorged Haemaphysalis flava ticks
    Yu Zhao, Zhe-Hui Qu, Feng-Chao Jiao
    Parasitology International.2021; 83: 102344.     CrossRef
  • Characterization of AV422 from Haemaphysalis flava ticks in vitro
    Lei Liu, Hao Tang, De-yong Duan, Jin-bao Liu, Jie Wang, Li-li Feng, Tian-yin Cheng
    Experimental and Applied Acarology.2021; 84(4): 809.     CrossRef
  • iSeq 100 for metagenomic pathogen screening in ticks
    Ju Yeong Kim, Myung-hee Yi, Alghurabi Areej Sabri Mahdi, Tai-Soon Yong
    Parasites & Vectors.2021;[Epub]     CrossRef
  • Study on the Epidemiological Features of Lyme Disease in Korea between 2011 and 2018
    Choong Won Seo
    The Korean Journal of Clinical Laboratory Science.2019; 51(4): 436.     CrossRef
  • Cathepsin L—a novel cysteine protease from Haemaphysalis flava Neumann, 1897
    Yali Sun, Lan He, Long Yu, Jiaying Guo, Zheng Nie, Qin Liu, Junlong Zhao
    Parasitology Research.2019; 118(5): 1581.     CrossRef
  • Tick saliva microbiomes isolated from engorged and partially fed adults ofHaemaphysalis flavatick females
    X.-M. He, T.-Y. Cheng
    Journal of Applied Entomology.2018; 142(1-2): 173.     CrossRef
  • Molecular detection of Rickettsia species in ticks collected from the southwestern provinces of the Republic of Korea
    Yoontae Noh, Yeong Seon Lee, Heung-Chul Kim, Sung-Tae Chong, Terry A. Klein, Ju Jiang, Allen L. Richards, Hae Kyeong Lee, Su Yeon Kim
    Parasites & Vectors.2017;[Epub]     CrossRef
  • Borrelia Species Detected in Ticks Feeding on Wild Korean Water Deer (Hydropotes inermis) Using Molecular and Genotypic Analyses
    D. VanBik, S. H. Lee, M. G. Seo, B. R. Jeon, Y. K. Goo, S. J. Park, M. H. Rhee, O. D. Kwon, T. H. Kim, P.J.L. Geraldino, D. Kwak
    Journal of Medical Entomology.2017; 54(5): 1397.     CrossRef
  • Serological Detection of Borrelia burgdorferi among Horses in Korea
    Seung-Hun Lee, Sun-Hee Yun, Eunsang Choi, Yong-Soo Park, Sang-Eun Lee, Gil-Jae Cho, Oh-Deog Kwon, Dongmi Kwak
    The Korean Journal of Parasitology.2016; 54(1): 97.     CrossRef
  • De novo assembly and analysis of midgut transcriptome of Haemaphysalis flava and identification of genes involved in blood digestion, feeding and defending from pathogens
    Xing-Li Xu, Tian-Yin Cheng, Hu Yang, Zhi-Hui Liao
    Infection, Genetics and Evolution.2016; 38: 62.     CrossRef
  • Enolase, a plasminogen receptor isolated from salivary gland transcriptome of the ixodid tick Haemaphysalis flava
    Xing-Li Xu, Tian-Yin Cheng, Hu Yang
    Parasitology Research.2016; 115(5): 1955.     CrossRef
  • Seasonal Patterns of Ticks in Pocheon and Cheolwon, Republic of Korea
    Yong Chil Shin, In Yong Lee, Jang Hoon Seo
    Korean Journal of Clinical Laboratory Science.2015; 47(3): 147.     CrossRef
  • Epidemiological Features and Clinical Manifestations of Lyme Borreliosis in Korea during the Period 2005^|^ndash;2012
    Shinje Moon, Yeongseon Hong, Kyu-Jam Hwang, Suyeon Kim, Jihye Eom, Donghyok Kwon, Ji-Hyuk Park, Seung-Ki Youn, Aeree Sohn
    Japanese Journal of Infectious Diseases.2015; 68(1): 1.     CrossRef
  • Insight into the Pathogenesis of Lyme Disease
    Ok Sarah Shin
    Journal of Bacteriology and Virology.2014; 44(1): 10.     CrossRef
  • Epidemic Intelligence Service Officers and Field Epidemiology Training Program in Korea
    Geun-Yong Kwon, Shinje Moon, Wooseok Kwak, Jin Gwack, Chaeshin Chu, Seung-Ki Youn
    Osong Public Health and Research Perspectives.2013; 4(4): 215.     CrossRef

PHRP : Osong Public Health and Research Perspectives