Search
- Page Path
- HOME > Search
- Characterization of
Clostridium difficile Strains Isolated from Patients withC. difficile -associated Disease in Korea - Seung-Hak Cho, Jung-Whan Chon, Kun-Ho Seo, Young Kwon Kim, Jung-Beom Kim, Young-Seok Bak, Woon-Won Jung, Cheorl-Ho Kim, Jong Tae Choi
- Osong Public Health Res Perspect. 2017;8(5):325-331. Published online October 31, 2017
- DOI: https://doi.org/10.24171/j.phrp.2017.8.5.06
- 4,861 View
- 35 Download
- 1 Crossref
-
Abstract
PDF Objectives Studies on
Clostridium difficile are rare in Korea. We investigated the epidemiological characteristics ofC. difficile isolates from patients withC. difficile -associated disease (CDAD) in Korea.Methods Multiplex polymerase chain reaction was performed to detect the presence of
tcdA andtcdB toxin genes. Antimicrobial susceptibility test was carried out by the disk-dilution method.C. difficile strains were subtyped by automated repetitive-element palindromic PCR (rep-PCR).Results Among patients with CDAD, 73 (25.8%), 32 (11.3%), 32 (11.3%), and 26 (9.2%) suffered from pneumonia, cancer or neoplasm, diabetes, and colitis, respectively. Of all stool samples, 43 samples (15.2%) were positive for
C. difficile strains. We observed two expression patterns of toxin genes:tcdA +/tcdB + (86% isolates) andtcdA −/tcdB + (14% isolates), with all isolates expressingtcdB . Furthermore, some isolates were resistant to clindamycin (65%), ampicillin (56%), and cefazolin (40%), but all were susceptible to vancomycin and metronidazole. The tested samples were classified into diverse clusters using automated rep-PCR.Conclusion Our findings revealed the characteristics and antibiotic resistance of
C. difficile isolates from patients in Korea. The epidemiological data may provide valuable insight into development of treatment strategies forC. difficile infections in Korea.-
Citations
Citations to this article as recorded by
- Metronidazole therapy as initial treatment of Clostridium difficile infection in patients with chronic kidney disease in Korea
Jaeuk Shin, Yu Mi Wi, Yu-Ji Lee
Epidemiology and Infection.2019;[Epub] CrossRef
- Metronidazole therapy as initial treatment of Clostridium difficile infection in patients with chronic kidney disease in Korea
- Antibiotic Resistance Patterns and Serotypes of
Salmonella spp. Isolated at Jeollanam-do in Korea - Ki-Bok Yoon, Byung-Joon Song, Mi-Yeong Shin, Hyun-Cheol Lim, Yeon-Hee Yoon, Doo-Young Jeon, Hoon Ha, Soo-In Yang, Jung-Beom Kim
- Osong Public Health Res Perspect. 2017;8(3):211-219. Published online June 30, 2017
- DOI: https://doi.org/10.24171/j.phrp.2017.8.3.08
- 6,165 View
- 48 Download
- 17 Crossref
-
Abstract
PDF
Objectives Few long-term studies have been conducted on the serotype and antibiotic resistance patterns of
Salmonella speices (spp.) The aim of this study was to determine the serotypes and antibiotic resistance patterns ofSalmonella spp. isolated at Jeollanam-do in Korea from 2004 to 2014.Methods A total of 276
Salmonella samples were evaluated. Serotyping was carried out according to the Kauffmann–White scheme. Antibiotic susceptibility was determined using the Vitek II system with an AST-N169 card.Results A total of 22 different serotypes were identified, and the major serotypes were
Salmonella Enteritidis (116 strains, 42.0%) andSalmonella Typhimurium (60 strains, 21.7%). The highest resistance was observed in response to nalidixic acid (43.4%), followed by ampicillin (40.5%) and tetracycline (31.6%). Resistance to nalidixic acid was detected in 81.0% ofS . Enteritidis. Multidrug resistance was detected in 43.3% ofSalmonella spp.S . Enteritidis andS . Typhimurium presented the highest resistance (98.3%) and multidrug resistance rate (73.3%), respectively. The most highly observed antibiotic resistance pattern amongSalmonella spp. in this study was ampicillin-chloramphenicol (14 strains, 5.7%),Conclusion Overall,
S . Enteritidis andS . Typhimurium showed higher antibiotic resistance than the otherSalmonella serotypes tested in this study. Our study will provide useful information for investigating the sources ofSalmonella infections, as well as selecting effective antibiotics for treatment.-
Citations
Citations to this article as recorded by- Serotype Occurrence, Virulence Profiles, Antimicrobial Resistance and Molecular Characterization of Salmonella Isolated from Hospitalized Patients with Gastroenteritis in Great Tunisia between 2010 and 2020
Walid Oueslati, Mohamed Ridha Rjeibi, Hayet Benyedem, Mounir Jebali, Fatma Souissi, Rachid Selmi, Mohamed Sélim El Asli, Farouk Barguellil, Abdelfettah Ettriqui
Antibiotics.2023; 12(3): 526. CrossRef - Prevalence and antimicrobial resistance of Salmonella enterica serovars Enteritidis and Typhimurium isolated from retail chicken meat in Wasit markets, Iraq
Manal H. G. Kanaan
Veterinary World.2023; : 455. CrossRef - In Vitro Characterization of Probiotic Potential of Limosilactobacillus fermentum against Salmonella Gallinarum Causing Fowl Typhoid
Adnan Mehmood, Muhammad Nawaz, Masood Rabbani, Muhammad Hassan Mushtaq
Animals.2023; 13(8): 1284. CrossRef - Prevalence and antimicrobial resistance of Salmonella spp. isolated from duck farms in Jeollanam-do Province, South Korea
Sin-Wook Park, Keon Kim, Chang-Yun Je, Chang-Hyeon Choi, Sang-Gyue Choi, Jong-Soo Lim, Ok-Mi Jeong, Guk-Hyun Suh, Chang-Min Lee
Korean Journal of Veterinary Service.2023; 46(3): 211. CrossRef - Trends in ESBLs and PABLs among enteric Salmonella isolates from children in Gwangju, Korea: 2014–2018
Kwang Gon Kim, Jin Jung, Ji Hyun Shin, Hye Jung Park, Min Ji Kim, Jin Jong Seo, Young Ok Kim, Su-Ya Lee, Chang-Yee Cho, Tae Sun Kim
Journal of Microbiology, Immunology and Infection.2022; 55(2): 199. CrossRef - Serotype Distribution and Antimicrobial Resistance of Salmonella Isolates in Korea between 2016 and 2017
Si Hyun Kim, Gyung-Hye Sung, Eun Hee Park, In Yeong Hwang, Gyu Ri Kim, Sae Am Song, Hae Kyung Lee, Young Uh, Young Ah Kim, Seok Hoon Jeong, Jong Hee Shin, Kyeong Seob Shin, Jaehyeon Lee, Joseph Jeong, Young Ree Kim, Dongeun Yong, Miae Lee, Yu Kyung Kim, N
Annals of Laboratory Medicine.2022; 42(2): 268. CrossRef - Clinically healthy household dogs and cats as carriers of multidrug-resistant Salmonella enterica with variable R plasmids
Thanich Chantharothaiphaichit, Dusadee Phongaran, Sunpetch Angkittitrakul, Surasit Aunpromma, Rungtip Chuanchuen
Journal of Medical Microbiology .2022;[Epub] CrossRef - [Retracted] CRISPR‐Cas System: An Adaptive Immune System’s Association with Antibiotic Resistance in Salmonella enterica Serovar Enteritidis
Muhammad Zulqarnain Haider, Muhammad Abu Bakr Shabbir, Tahir Yaqub, Adeel Sattar, Muhammad Kashif Maan, Sammina Mahmood, Tahir Mehmood, Hassaan Bin Aslam, Abdelmotaleb Elokil
BioMed Research International.2022;[Epub] CrossRef - Phenotypic and molecular characterization of Salmonella Enteritidis isolates
Alper KARAGÖZ, Levent ALTINTAŞ, Tutku ARSLANTAŞ, Hidayet TUTUN, Nadir KOÇAK, Özlem ALTINTAŞ
Ankara Üniversitesi Veteriner Fakültesi Dergisi.2021; 68(2): 113. CrossRef - Модели антибиотикорезистентности сальмонелл
А. М. Мендыбаева, Р. М. Рыщанова, P. O. Сеилханова
Innovations and Food Safety.2021; (3): 14. CrossRef - Prevalence of fluoroquinolone-resistantSalmonellaserotypes in Iran: a meta-analysis
Farzad Khademi, Hamid Vaez, Fahimeh Ghanbari, Mohsen Arzanlou, Jafar Mohammadshahi, Amirhossein Sahebkar
Pathogens and Global Health.2020; 114(1): 16. CrossRef - Systematic Evaluation of Whole Genome Sequence-Based Predictions of Salmonella Serotype and Antimicrobial Resistance
Ashley L. Cooper, Andrew J. Low, Adam G. Koziol, Matthew C. Thomas, Daniel Leclair, Sandeep Tamber, Alex Wong, Burton W. Blais, Catherine D. Carrillo
Frontiers in Microbiology.2020;[Epub] CrossRef - Prevalence of antibiotic resistant Salmonella spp. strains in shrimp farm source waters of Nagapattinam region in South India
Akalesh Patel, Geevaretnam Jeyasekaran, Robinson Jeyashakila, Theivasigamani Anand, Lidiya Wilwet, Neeraj Pathak, Asha Hema Malini, Neethirajan Neethiselvan
Marine Pollution Bulletin.2020; 155: 111171. CrossRef - Characterization and Antimicrobial Resistance of Escherichia coli and Its Serotypes Isolated from Poultry Feed in Relation to Seasons in Karachi, Pakistan
Shajeela Iram, Mehmood ul Hassan, Tabinda Khawaja
Jundishapur Journal of Health Sciences.2020;[Epub] CrossRef - Identifying the mechanism underlying treatment failure for Salmonella Paratyphi A infection using next-generation sequencing – a case report
Hye-Ran Park, Dong-Min Kim, Na-Ra Yun, Choon-Mee Kim
BMC Infectious Diseases.2019;[Epub] CrossRef - Characteristics of third-generation cephalosporin-resistant Salmonella from retail chicken meat produced by integrated broiler operations
Hye Young Jeon, Kwang Won Seo, Yeong Bin Kim, Dong Kyu Kim, Shin Woo Kim, Young Ju Lee
Poultry Science.2019; 98(4): 1766. CrossRef - Comparative Study on Antibiotic Resistance and DNA Profiles ofSalmonella entericaSerovar Typhimurium Isolated from Humans, Retail Foods, and the Environment in Shanghai, China
Zengfeng Zhang, Chenyang Cao, Bin Liu, Xuebin Xu, Yanfei Yan, Shenghui Cui, Sheng Chen, Jianghong Meng, Baowei Yang
Foodborne Pathogens and Disease.2018; 15(8): 481. CrossRef
- Serotype Occurrence, Virulence Profiles, Antimicrobial Resistance and Molecular Characterization of Salmonella Isolated from Hospitalized Patients with Gastroenteritis in Great Tunisia between 2010 and 2020
First
Prev
