<b>Objectives</b><br/>
Fatigue is the most frequently reported symptom experienced by cancer patients and has a profound effect on their quality of life (QOL). The study aimed to determine the impact of fatigue on QOL among breast cancer patients receiving chemotherapy and to identify the risk factors associated with severe fatigue incidence.
<br/><b>Methods</b><br/>
This was an observational prospective study carried out at multiple centers. In total, 172 breast cancer patients were included. The Functional Assessment of Chronic Illness Therapy-Fatigue Questionnaire was used to measure QOL, while the Brief Fatigue Inventory (BFI) was used to assess the severity of fatigue.
<br/><b>Results</b><br/>
The total average mean and standard deviation of QOL were 84.58±18.07 and 4.65±1.14 for BFI scores, respectively. A significant association between fatigue and QOL was found in linear and multiple regression analyses. The relationships between fatigue severity and cancer stage, chemotherapy dose delay, dose reduction, chemotherapy regimen, and ethnicity were determined using binary logistic regression analysis.
<br/><b>Conclusion</b><br/>
The findings of this study are believed to be useful for helping oncologists effectively evaluate, monitor, and treat fatigue related to QOL changes.
Citations
Citations to this article as recorded by
Factors affecting quality of life in women post mastectomy for breast cancer in Baheya Foundation (Egypt): ‘A retrospective cohort study’ Salsabil Mohammed Abdelrahman, Maher Hassan Ibraheem, Hemat Allam, Vikash Sewram BMC Women's Health.2025;[Epub] CrossRef
Specification of self-reported late-term impairments 3–7 years after primary breast cancer treatment: a nationwide cross-sectional study among Danish breast cancer survivors Kim Michéle Feder, Kim Gordon Ingwersen, Hans Bjarke Rahr, Heidi Klakk Egebæk, Lonny Stokholm, Marianne Djernes Lautrup Journal of Cancer Survivorship.2025;[Epub] CrossRef
Effectiveness of Therapeutic Exercise Models on Cancer-Related Fatigue in Patients With Cancer Undergoing Chemotherapy: A Systematic Review and Network Meta-analysis Aida Herranz-Gómez, Ferran Cuenca-Martínez, Luis Suso-Martí, Clovis Varangot-Reille, Miriam Prades-Monfort, Joaquín Calatayud, Jose Casaña Archives of Physical Medicine and Rehabilitation.2023; 104(8): 1331. CrossRef
Anatomical Sites OF Superficial Basal Cell Cancers Demonstrate Higher Rates of Mixed Histology Zahid Sarfaraz Khan, Asim Muhammad, Muhammad Ataullah, Syeda Gulrukh Saba Shah, Tehmina Naushin, Hina Mir, Nabiha Naeem, Ziyad Ahmad, Sudhair Abbas Bangash, Irfan Ullah Pakistan BioMedical Journal.2022; : 44. CrossRef
Glycated Albumin's Clinical Effectiveness in The Diabetes Diagnosis Summeira Jabeen Shah, Hajira Ishaq, Hina Hakeem, Saima Shaheen, Sikandar Ali Khan, Sosan Rauf, Hina Mir, Sudhair Abbas Bangash, Muhammad Ali, Irfan Ullah Pakistan BioMedical Journal.2022; : 176. CrossRef
Post stroke intervention trial in fatigue (POSITIF): Randomised multicentre feasibility trial Gillian Mead, David Gillespie, Mark Barber, Allan House, Steff Lewis, Hannah Ensor, Simiao Wu, Trudie Chalder Clinical Rehabilitation.2022; 36(12): 1578. CrossRef
Quality of Life and Its Associated Factors Among Cancer Patients Receiving Chemotherapy at Oncology Hospitals in Vietnam After the Third Wave of the COVID-19 Pandemic Hanh TH Nguyen, Khanh Linh Duong, Son T Nguyen, Quy Trinh, Hao TL Hoang, Toan Q Phung, Hsiang-Wen Lin, Huong TL Nguyen Cancer Management and Research.2022; Volume 14: 2429. CrossRef
Effects of traditional Chinese medicine exercise therapy on cancer-related fatigue, anxiety and sleep quality in cancer patients Lihao Jiang, Ju Ouyang, Xianfeng Du Medicine.2021; 100(44): e27681. CrossRef