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Alterations of gyrA, gyrB, and parC and Activity of Efflux Pump in Fluoroquinolone-resistant Acinetobacter baumannii
Sunok Park, Kyeong Min Lee, Yong Sun Yoo, Jung Sik Yoo, Jae Il Yoo, Hwa Su Kim, Yeong Seon Lee, Gyung Tae Chung
Osong Public Health Res Perspect. 2011;2(3):164-170.   Published online December 31, 2011
Objectives This study investigated the fluoroquinolone-resistant mechanism of 56 clinical cases of A baumannii infection from 23 non-tertiary hospitals, collected between 2004 and 2006. Methods Susceptibility testing was performed by broth microdilution and Epsilometer test. Analyses of quinolone resistance-determining region (QRDR) were done by sequencing. The activity of the efflux pump was measured using inhibitors. Results The sequences from selected 56 isolates were divided into...
Original Article
Gene Expression and Identification Related to Fluconazole Resistance of Candida glabrata Strains
Jae Il Yoo, Chi Won Choi, Kyeong Min Lee, Yeong Seon Lee
Osong Public Health Res Perspect. 2010;1(1):36-41.   Published online December 31, 2010
Objectives Candida glabrata has become one of the most common causes of Candida bloodstream infections worldwide. Some strains of C. glabrata may be intermediately resistant to all azoles. The several possible mechanisms of azole resistance have been reported previously, but the exact resistant mechanism is not clear. In this study, we identified differentially expressed genes (DEGs) of fluconazole-resistant C. glabrata and...

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Print ISSN: 2210-9099
Online ISSN: 2233-6052

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