Search

  • HOME
  • Search
Brief Report
Ebola Hemorrhagic Fever and the Current State of Vaccine Development
Joo Eun Hong, Kee-Jong Hong, Woo Young Choi, Won-Ja Lee, Yeon Hwa Choi, Chung-Hyeon Jeong, Kwang-il Cho
Osong Public Health Res Perspect. 2014;5(6):378-382.   Published online December 31, 2014
Current Ebola virus outbreak in West Africa already reached the total number of 1,323 including 729 deaths by July 31st. the fatality is around 55% in the southeastern area of Guinea, Sierra Leone, Liberia, and Nigeria. The number of patients with Ebola Hemorrhagic Fever (EHF) was continuously increasing even though the any effective therapeutics or vaccines has not been developed...
Articles
Serological Correlate of Protection in Guinea Pigs for a Recombinant Protective Antigen Anthrax Vaccine Produced from Bacillus brevis
Jeong-Hoon Chun, On-Jee Choi, Min-Hee Cho, Kee-Jong Hong, Won Keun Seong, Hee-Bok Oh, Gi-Eun Rhie
Osong Public Health Res Perspect. 2012;3(3):170-176.   Published online June 30, 2012
Objective Recombinant protective antigen (rPA) is the active pharmaceutical ingredient of a second generation anthrax vaccine undergoing clinical trials both in Korea and the USA. By using the rPA produced from Bacillus brevis pNU212 expression system, correlations of serological immune response to anthrax protection efficacy were analyzed in a guinea pig model. Methods Serological responses of rPA anthrax vaccine were investigated in guinea...
In vivo Noninvasive Small Animal Molecular Imaging
Hyewon Youn, Kee-Jong Hong
Osong Public Health Res Perspect. 2012;3(1):48-59.   Published online December 31, 2011
The remarkable efforts that are made on molecular imaging technologies demonstrate its potential importance and range of applications. The generation of disease-specific animal models, and the developments of target-specific probes and genetically encoded reporters are another important component. Continued improvements in the instrumentation, the identification of novel targets and genes, and the availability of improved imaging probes should be made....
Original Article
Ingenol Protects Human T Cells From HIV-1 Infection
Kee-Jong Hong, Hak Sung Lee, Yeong-shik Kim, Sung Soon Kim
Osong Public Health Res Perspect. 2011;2(2):109-114.   Published online June 30, 2011
Objectives Many natural compounds have been investigated as drug candidates to prevent human immunodeficiency virus (HIV) with low cytotoxicity. We tested whether ingenol from Euphorbia ingens exerts anti-HIV effects in human T cell lines. Methods and Results Ingenol effectively maintained high cell viability (CD50, >1 mM) in H9 and MT4 T cells. The efficacy of ingenol to inhibit HIV-1 infection was dose dependent. ED50 for 100...

Osong Public
Health and
Research
Perspectives

Print ISSN: 2210-9099
Online ISSN: 2233-6052

  • PubMed Central
  • PubMed
  • DOAJ (Directory of Open Access Journals)
  • Embase
  • Scopus
  • EBSCO
  • KoreaMed
  • KoMCI
  • GoogleScholar
  • Similarity Check
  • Crossref Cited-by Linking
  • CrossMark
  • Funder Registry
  • ORCID


About
Articles and Issues
Editorial policies
For authors
 
Editorial Office
Korea Disease Control and Prevention Agency
National Center for Medical Information and Knowledge,
202, Ossongsengmyung 2nd street, Osong eup, Heungdeok gu, Cheongju si, Chungcheongbuk do 28159, Korea
E-mail: ophrp@korea.kr

Copyright © 2021 by Korea Disease Control and Prevention Agency.

Close layer