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Cyclophilin A Cpr1 Protein Modulates the Response of Antioxidant Molecules to Menadione-induced Oxidative Stress in Saccharomyces cerevisiae KNU5377Y
Il-Sup Kim, Haesun Yun, Ingnyol Jin, Ho-Sung Yoon
Osong Public Health Res Perspect. 2011;2(3):171-177.   Published online December 31, 2011
Objectives The cellular function of cyclophilin A (CypA) differs between organisms, even though CypA is conserved in both prokaryotes and eukaryotes. The purpose of this study was to elucidate the role of activated CypA isoform CPR1 in the antioxidative mechanisms of Saccharomyces cerevisiae under menadione (MD)-induced oxidative stress. Methods Four S. cerevisiae strains, KNU5377Y (kwt) and BY4741 (bwt), and their isogenic cpr1⊿ mutant...

Osong Public
Health and

Print ISSN: 2210-9099
Online ISSN: 2233-6052

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