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Volume 9(6); December 2018
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Editorial
How Much Caffeine is Too Much for Young Adolescents?
Hae-Wol Cho
Osong Public Health Res Perspect. 2018;9(6):287-288.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.01
  • 4,326 View
  • 65 Download
  • 2 Citations
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  • Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components
    Zahra A. Barandouzi, Joochul Lee, Kendra Maas, Angela R. Starkweather, Xiaomei S. Cong
    Journal of Personalized Medicine.2021; 11(1): 35.     CrossRef
  • Effects of Chronic Caffeine Administration on Behavioral and Molecular Adaptations to Sensory Contact Model Induced Stress in Adolescent Male Mice
    Michael Kamal Ibrahim, Mohamed Kamal, Rajiv Tikamdas, Roua Aref Nouh, Jiang Tian, Moustafa Sayed
    Behavior Genetics.2020; 50(5): 374.     CrossRef
Original Articles
Obesity, Hypertension, and Type-2 Diabetes Mellitus: The Interrelationships and the Determinants among Adults in Gaza City, Palestine
Mohammed S. Ellulu
Osong Public Health Res Perspect. 2018;9(6):289-298.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.02
  • 4,043 View
  • 112 Download
  • 6 Citations
AbstractAbstract PDF
Objectives

To describe the distribution of social factors, lifestyle habits and anthropometric measurements according to hypertension and Type-2 diabetes.

Methods

A cross-sectional study was conducted in Gaza City, Palestine that included 379 patients (20–60 years) who had hypertension and/or diabetes. Three groups of patients were involved; 106 hypertensive (HT), 109 diabetic (T2DM) and 164 hypertensive diabetics (HT + T2DM).

Results

The HT + T2DM group were older and had a higher body mass index compared to HT and T2DM groups. There were 62.3% patients who were female, 49.2% were highly educated HT patients, and 49.3% patients had a low level of education and were HT + T2DM. There were 55.8% patients who lived in large families. Patients who were passive smokers or never smoked before were mostly HT + T2DM, while active smokers and past smokers had T2DM. There were 48.2% patients who were highly physically active who had HT, 40.9% whom were moderately active had T2DM, and 53.8% of patients who had a low level of activity were HT + T2DM. Multivariate linear regression showed that having a diseased mother, living in a large family, being a past or passive smoker, or never having smoked, having a low or moderate level of activity, and having HT or HT + T2DM, were significantly associated with an increased body mass index.

Conclusion

Parental health/disease conditions and environmental factors (social network and lifestyle habits) played the greatest role in the development of obesity and disease.

Citations

Citations to this article as recorded by  
  • The hypertension cascade of care in the midst of conflict: the case of the Gaza Strip
    Bassam A. Abu Hamad, Zeina Jamaluddine, Gloria Safadi, Marie-Elizabeth Ragi, Raeda El Sayed Ahmad, Eszter P. Vamos, Sanjay Basu, John S. Yudkin, Mohammed Jawad, Christopher Millett, Hala Ghattas
    Journal of Human Hypertension.2022;[Epub]     CrossRef
  • Association between endothelial nitric oxide synthase and the renin-angiotensin-aldosterone system polymorphisms, blood pressure and training status in normotensive/pre-hypertension and hypertensive older adults: a pilot study
    Roberta Fernanda da Silva, Riccardo Lacchini, Lucas Cezar Pinheiro, Letícia Perticarrara Ferezin, José Eduardo Tanus-Santos, Marcelo Rizzatti Luizon, Thiago José Dionísio, Carlos Ferreira Santos, Thaís Amanda Reia, André Mourão Jacomini, Ana Maria Guilmo
    Clinical and Experimental Hypertension.2021; 43(7): 661.     CrossRef
  • Breakfast characteristics, perception, and reasons of skipping among 8th and 9th-grade students at governmental schools, Jenin governance, West Bank
    Manal Badrasawi, Ola Anabtawi, Yaqout Al-Zain
    BMC Nutrition.2021;[Epub]     CrossRef
  • Advanced Molecular Imaging (MRI/MRS/1H NMR) for Metabolic Information in Young Adults with Health Risk Obesity
    Khin Thandar Htun, Jie Pan, Duanghathai Pasanta, Montree Tungjai, Chatchanok Udomtanakunchai, Thanaporn Petcharoen, Nattacha Chamta, Supak Kosicharoen, Kiattisak Chukua, Christopher Lai, Suchart Kothan
    Life.2021; 11(10): 1035.     CrossRef
  • Prevalence and Predictors of Co-occurring Hypertension and Depression Among Community-Dwelling Older Adults
    Cicily A. Gray, Omar T. Sims, Hyejung Oh
    Journal of Racial and Ethnic Health Disparities.2020; 7(2): 365.     CrossRef
  • Prevalence of Type 2 Diabetes and Its Association with Added Sugar Intake in Citizens and Refugees Aged 40 or Older in the Gaza Strip, Palestine
    Majed Jebril, Xin Liu, Zumin Shi, Mohsen Mazidi, Akram Altaher, Youfa Wang
    International Journal of Environmental Research an.2020; 17(22): 8594.     CrossRef
Health Related Nutritional Knowledge and Dietary Behavior Regarding Caffeine Intake among High School Students in Yongin Region
Seong Yeong Kim
Osong Public Health Res Perspect. 2018;9(6):299-308.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.03
  • 3,756 View
  • 33 Download
  • 2 Citations
AbstractAbstract PDF
Objectives

We aimed to examine health-related nutritional knowledge and dietary behavior related to caffeine intake among high school students (n = 310) in the Yongin region of Korea.

Methods

Data were collected using a face-to-face survey, and analyzed using chi-square test, t- test, and logistic regression analysis.

Results

The level of caffeine intake in respondents was divided into low (< 30 mg/d; n = 208) and high caffeine intake groups (> 30 mg/d; n = 102). Total nutritional knowledge related to bone disease was higher in the low intake group (score 2.75) than the high intake group (score 2.39; p < 0.05). The high intake group had lower scores for nutritional knowledge (score 0.70; p < 0.05) related to how caffeinated beverages affect sleep and for dietary behavior (score 3.25; p < 0.001), based on “I avoid caffeinated foods before sleep,” than the low intake group (nutritional knowledge score, 0.80; dietary behavior score, 3.76).

Conclusion

In the overall analysis, the low caffeine intake group had better nutritional knowledge related to bone and sleep health, and healthier dietary behavior related to sleep health compared with the high intake group.

Citations

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  • TINGKAT PENGETAHUAN EFEK KONSUMSI KAFEIN DAN ASUPAN KAFEIN PADA MAHASISWA
    Sarah Stephanie Br Ginting, Yunisa Astiarani, Bryany Titi Santi, Vetinly Vetinly
    Journal of Nutrition College.2022; 11(4): 264.     CrossRef
  • Caffeine Consumption in a Group of Adolescents from South East Poland—A Cross Sectional Study
    Ewa Błaszczyk-Bębenek, Paweł Jagielski, Małgorzata Schlegel-Zawadzka
    Nutrients.2021; 13(6): 2084.     CrossRef
Neck Pain in Adults with Forward Head Posture: Effects of Craniovertebral Angle and Cervical Range of Motion
Dae-Hyun Kim, Chang-Ju Kim, Sung-Min Son
Osong Public Health Res Perspect. 2018;9(6):309-313.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.04
  • 5,523 View
  • 147 Download
  • 30 Citations
AbstractAbstract PDF
Objectives

The purpose of this study was to determine whether the cranial vertebral angle (CVA) and the range of motion (ROM) was different between participants with a forward head posture (FHP), with or without pain.

Methods

Forty-four participants who had FHP participated in this study. The FHP was assessed digitally by measuring a lateral view the CVA for each subject. A cervical ROM device measured the cervical ROM. The volunteers were allocated to either, with pain (n = 22), or without pain (n = 22) groups, and pain was evaluated using the Numeric Pain Rating Scale.

Results

The FHP in the pain group showed a significant difference in the CVA, and the cervical ROM in both flexion and extension, compared with those in the FHP without pain group (p < 0.05). Logistic regression analysis indicated that the occurrence of cervical area pain was higher amongst subjects who had a decreased CVA and flexion motion.

Conclusion

This study suggested that decreased CVA and cervical flexion range, were predictive factors for the occurrence of pain in the cervical region.

Citations

Citations to this article as recorded by  
  • Social Media Devices’ Influence on User Neck Pain during the COVID-19 Pandemic: Collaborating Vertebral-GLCM Extracted Features with a Decision Tree
    Bassam Al-Naami, Bashar E. A. Badr, Yahia Z. Rawash, Hamza Abu Owida, Roberto De Fazio, Paolo Visconti
    Journal of Imaging.2023; 9(1): 14.     CrossRef
  • Musculoskeletal disorders and functional characteristics of the neck and shoulder: Comparison between office workers using a laptop or desktop computer
    Martin Argus, Mati Pääsuke
    Work.2023; : 1.     CrossRef
  • Is Neck Pain Related to Sagittal Head and Neck Posture?: A Systematic Review and Meta-analysis
    Babina Rani, Abhijit Paul, Anil Chauhan, Pranita Pradhan, Mandeep S. Dhillon
    Indian Journal of Orthopaedics.2023;[Epub]     CrossRef
  • Effects of carrying school bags on cervical and shoulder posture in static and dynamic conditions in adolescent students
    Shivani Mandrekar, Dinesh Chavhan, Ashok K. Shyam, Parag K. Sancheti
    International Journal of Adolescent Medicine and H.2022;[Epub]     CrossRef
  • Forward flexed posture: reliability and determinants of tragus-to-wall measurement
    Frank T. Tudini, Bradley J. Myers, Richard W. Bohannon
    Physiotherapy Theory and Practice.2022; 38(4): 579.     CrossRef
  • Investigation on the biomechanical behaviour of the lower cervical spine induced by facet tropism with respect to the sagittal plane
    Zhi Huang, Yali Zhang, Xin Rong, Xiaogang Zhang, Hao Liu, Zhongmin Jin
    Medical Engineering & Physics.2022; 102: 103779.     CrossRef
  • Effect of suboccipital release technique in forward head posture: A comparative study
    Amita Aggarwal, Ashwani Nair, TusharJ Palekar, Dhammapal Bhamare
    Medical Journal of Dr. D.Y. Patil Vidyapeeth.2022; 15(4): 534.     CrossRef
  • A comparison of muscle activity, posture and body discomfort during the use of different computer screen sizes
    Praphatson Sengsoon, Kanruethai Siriworakunsak
    International Journal of Occupational Safety and E.2022; : 1.     CrossRef
  • Aufrechte Haltung schützt nicht vor Nackenschmerz

    Schmerz.Therapie.2022; 5(02): 61.     CrossRef
  • Establishing minimal clinically important difference for effectiveness of corrective exercises on craniovertebral and shoulder angles among students with forward head posture: a clinical trial study
    Zahra Heydari, Rahman Sheikhhoseini, Shahnaz Shahrbanian, Hashem Piri
    BMC Pediatrics.2022;[Epub]     CrossRef
  • Effect Of Forward Head Posture with Neck Disability and Quality of Life in Freelancer
    Rabia Tasmeer, Syed Asad Ullah Arslan, Ashfaq Ahmad, Fareeha Amjad
    Pakistan BioMedical Journal.2022; : 288.     CrossRef
  • Evaluating Differences Between Participants With Various Forward Head Posture With and Without Postural Neck Pain Using Craniovertebral Angle and Forward Shoulder Angle
    Neda Mostafaee, Fatemeh HasanNia, Hossein Negahban, Nahid Pirayeh
    Journal of Manipulative and Physiological Therapeu.2022; 45(3): 179.     CrossRef
  • Prevalence Of Neck and Back Pain Among Gynecologists and Obstetrics in Tertiary Care Hospital of Lahore
    Rahat Afzal, Samrood Akram, Haseeb-Ur- Rehman, Anam Abbas, Muhammad Talha Hassan Javed, Hafiza Sana Ashraf
    Pakistan BioMedical Journal.2022; : 23.     CrossRef
  • A Study on the VR Goggle-based Vision System for Robotic Surgery
    Young Gyun Kim, Gyeongbin Mun, Myungjoon Kim, Byoungjun Jeon, Jong Hyeon Lee, Dan Yoon, Byeong Soo Kim, Seong-Ho Kong, Chang Wook Jeong, Kyu Eun Lee, Minwoo Cho, Sungwan Kim
    International Journal of Control, Automation and S.2022; 20(9): 2959.     CrossRef
  • Examining accuracy of and determining the best cutoff point for photographic-based postural angles to discriminate between slight and moderate-to-severe forward head posture
    Neda Mostafaee, Nahid Pirayeh, Fatemeh HasanNia, Hossein Negahban, Mahsa Kasnavi
    Physiotherapy Theory and Practice.2022; : 1.     CrossRef
  • Efficacy of physiotherapy intervention on craniovertebral and craniohorizontal angle using on protractor mobile app and neck muscle strength in chronic nonspecific neck pain
    Rajalaxmi V., Niranjana R, C.V. Senthil Nathan, G. Mohan Kumar
    Biomedicine.2022; 42(3): 589.     CrossRef
  • The incidence of work-related musculoskeletal pain among administrators in a South African university
    L.M. Moraba, T.J. Ellapen, Y. Paul
    African Journal for Physical Activity and Health S.2022; 28(3): 218.     CrossRef
  • Therapeutic and stabilization exercises after manual therapy in patients with non-specific chronic neck pain: A randomised clinical trial
    Okan Demir, Emine Atıcı, Mustafa Savaş Torlak
    International Journal of Osteopathic Medicine.2022; : 100639.     CrossRef
  • Severity of slouched posture during smartphone use is associated with the musculoskeletal discomfort, daily usage, and school year among adolescents
    Sharon M.H. Tsang, Gladys L.Y. Cheing, Jess W.K. Chan
    Ergonomics.2022; : 1.     CrossRef
  • Magnification loupes influence on neck and trunk flexion of dental hygienists while scaling—A pilot study
    Emily A Ludwig, Susan L Tolle, Eric Jenkins, Daniel Russell
    International Journal of Dental Hygiene.2021; 19(1): 106.     CrossRef
  • Morphometric characteristics of cervical vertebrae in subjects with short, normal, and long faces
    V. Anusuya, Jitendra Sharan, Ashok Kumar Jena
    Surgical and Radiologic Anatomy.2021; 43(6): 865.     CrossRef
  • Analysis of neck and back muscle activity during the application of various pillow designs in patients with forward head posture
    Sirirat Kiatkulanusorn, Bhornluck Paepetch Suato, Phurichaya Werasirirat
    Journal of Back and Musculoskeletal Rehabilitation.2021; 34(3): 431.     CrossRef
  • Relación entre los factores estáticos y dinámicos de la región cervical y escapular en el dolor de cuello en auxiliares administrativas de Areandina-Pereira 2020
    Libni Madai Mejía Morales, Melisa Torres Arias, Diana Marcela Marín Diaz, Angela María Rincón Hurtado, Yuber Andrés Gálvez Castaño, Tatiana Rodríguez Amador
    Cuaderno de investigaciones: semilleros andina.2021; (13): 168.     CrossRef
  • Is Neck Posture Subgroup in Late Adolescence a Risk Factor for Persistent Neck Pain in Young Adults? A Prospective Study
    Karen V Richards, Darren J Beales, Anne L Smith, Peter B O’Sullivan, Leon M Straker
    Physical Therapy.2021;[Epub]     CrossRef
  • Catering Work Profession and Medico-Oral Health: A Study on 603 Subjects
    Sabina Saccomanno, Stefano Mummolo, Silvia Giancaspro, Rebecca Jewel Manenti, Rodolfo Francesco Mastrapasqua, Giuseppe Marzo, Vincenzo Quinzi
    Healthcare.2021; 9(5): 582.     CrossRef
  • RELATION OF NECK PAIN, FORWARD HEAD POSITION AND PROTRACTED SHOULDERS IN STUDENTS WITH CHRONIC NECK PAIN.
    Ritika Save, Annamma Varghese (PT)
    INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2021; : 28.     CrossRef
  • Effects of Instrumental, Manipulative and Soft Tissue Approaches for the Suboccipital Region in Subjects with Chronic Mechanical Neck Pain. A Randomized Controlled Trial
    Juan José Arjona Retamal, Alejandro Fernández Seijo, José David Torres Cintas, Ana I. de-la-Llave-Rincón, Andrea Caballero Bragado
    International Journal of Environmental Research an.2021; 18(16): 8636.     CrossRef
  • Effect of forward head and rounded shoulder posture on hand grip strength in asymptomatic young adults: a cross-sectional study
    Dalia Mohammed Mosaad, Amr Almaz Abdel-aziem, Ghada Ismail Mohamed, Enas Anwr Abd-Elaty, Karima Salah Mohammed
    Bulletin of Faculty of Physical Therapy.2020;[Epub]     CrossRef
  • A review on the lactic acid fermentation from low-cost renewable materials: Recent developments and challenges
    Ashfaq Ahmad, Fawzi Banat, Hanifa Taher
    Environmental Technology & Innovation.2020; 20: 101138.     CrossRef
  • Reliability and validity of measurements of cervical retraction strength obtained with a hand-held dynamometer
    Frank Tudini, Bradley Myers, Richard Bohannon
    Journal of Manual & Manipulative Therapy.2019; 27(4): 222.     CrossRef
A Preliminary Study to Determine Comprehensive Research and Development Plans for Promoting Mental Health Services
Chul Eung Kim, Young-Mi Ko, Sang-Uk Lee, SungKu Choi, Kiwan Han, Se Jin Park, MinKyung Jo, Yu Kyong Park, Hye Young Lee, Subin Park
Osong Public Health Res Perspect. 2018;9(6):314-324.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.05
  • 5,507 View
  • 59 Download
AbstractAbstract PDF
Objectives

The aim of this study was to analyze research and development projects in mental health services in Korea, using priority evaluation of mental health promotion policies to determine direction of the service.

Methods

An online survey was conducted that targeted experts in the mental health service regarding promotion of mental health in Korea in 2016. The survey was based on 32 policy projects that resulted from 12 strategies according to 4 policy objectives.

Results

Analysis of 32 mental health projects were assessed regarding the possibility of technology development success, magnitude of the ripple effect, and necessity of a national response. It was observed that 3 policy projects relevant to suicide, had a high relative priority. This was followed by policies for improvement of health insurance and the medical benefit cost system, and policies for reinforcement of crisis psychological support such as those for disaster victims.

Conclusion

The prioritization of mental health services should place an emphasis on promotion of a healthy mental lifestyle, rehabilitation support for patients with serious mental illness, and reinforcement of social safety networks for suicide prevention.

Association between Beta-lactam Antibiotic Resistance and Virulence Factors in AmpC Producing Clinical Strains of P. aeruginosa
Sanaz Dehbashi, Hamed Tahmasebi, Mohammad Reza Arabestani
Osong Public Health Res Perspect. 2018;9(6):325-333.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.06
  • 21,561 View
  • 130 Download
  • 12 Citations
AbstractAbstract PDF
Objectives

The purpose of this study was to determine the presence of IMP and OXA genes in clinical strains of Pseudomonas aeruginosa (P. aeruginosa) that are carriers of the ampC gene.

Methods

In this study, 105 clinical isolates of P. aeruginosa were collected. Antibiotic resistance patterns were determined using the disk diffusion method. The strains carrying AmpC enzymes were characterized by a combination disk method. Multiplex-PCR was used to identify resistance and virulence genes, chi-square test was used to determine the relationship between variables.

Results

Among 105 isolates of P. aeruginosa, the highest antibiotic resistance was to cefotaxime and aztreonam, and the least resistance was to colictin and ceftazidime. There were 49 isolates (46.66%) that showed an AmpC phenotype. In addition, the frequencies of the resistance genes were; OXA48 gene 85.2%, OXA199, 139 3.8%, OXA23 3.8%, OXA2 66.6%, OXA10 3.8%, OXA51 85.2% and OXA58 3.8%. The IMP27 gene was detected in 9 isolates (8.57%) and the IMP3.34 was detected in 11 isolates (10.47%). Other genes detected included; lasR (17.1%), lasB (18%) and lasA (26.6%). There was a significant relationship between virulence factors and the OX and IMP genes (p ≤ 0.05).

Conclusion

The relationship between antibiotic resistance and virulence factors observed in this study could play an important role in outbreaks associated with P. aeruginosa infections.

Citations

Citations to this article as recorded by  
  • Molecular epidemiology and collaboration of siderophore-based iron acquisition with surface adhesion in hypervirulent Pseudomonas aeruginosa isolates from wound infections
    Hamed Tahmasebi, Sanaz Dehbashi, Mona Nasaj, Mohammad Reza Arabestani
    Scientific Reports.2022;[Epub]     CrossRef
  • Decoding Genetic Features and Antimicrobial Susceptibility of Pseudomonas aeruginosa Strains Isolated from Bloodstream Infections
    Tomasz Bogiel, Dagmara Depka, Mateusz Rzepka, Agnieszka Mikucka
    International Journal of Molecular Sciences.2022; 23(16): 9208.     CrossRef
  • Prevalence of the Genes Associated with Biofilm and Toxins Synthesis amongst the Pseudomonas aeruginosa Clinical Strains
    Tomasz Bogiel, Dagmara Depka, Mateusz Rzepka, Joanna Kwiecińska-Piróg, Eugenia Gospodarek-Komkowska
    Antibiotics.2021; 10(3): 241.     CrossRef
  • A Comprehensive Study of the Relationship between the Production of β-Lactamase Enzymes and Iron/Siderophore Uptake Regulatory Genes in Clinical Isolates of Acinetobacter baumannii
    Mahyar Porbaran, Hamed Tahmasebi, MohammadReza Arabestani, Joseph Falkinham
    International Journal of Microbiology.2021; 2021: 1.     CrossRef
  • Regulation of virulence and β-lactamase gene expression in Staphylococcus aureus isolates: cooperation of two-component systems in bloodstream superbugs
    Sanaz Dehbashi, Hamed Tahmasebi, Behrouz Zeyni, Mohammad Reza Arabestani
    BMC Microbiology.2021;[Epub]     CrossRef
  • New approach to identify colistin‐resistant Pseudomonas aeruginosa by high‐resolution melting curve analysis assay
    H. Tahmasebi, S. Dehbashi, M.R. Arabestani
    Letters in Applied Microbiology.2020; 70(4): 290.     CrossRef
  • Resistant Pseudomonas aeruginosa carrying virulence genes in hospitalized patients with urinary tract infection from Sanandaj, west of Iran
    Safoura Derakhshan, Aslan Hosseinzadeh
    Gene Reports.2020; 20: 100675.     CrossRef
  • Prevalence and molecular typing of Metallo-β-lactamase-producing Pseudomonas aeruginosa with adhesion factors: A descriptive analysis of burn wounds isolates from Iran
    Hamed Tahmasebi, Sanaz Dehbashi, Mohammad Yousef Alikhani, Mahyar Porbaran, Mohammad Reza Arabestani
    Gene Reports.2020; 21: 100853.     CrossRef
  • Co-harboring of mcr-1 and β-lactamase genes in Pseudomonas aeruginosa by high-resolution melting curve analysis (HRMA): Molecular typing of superbug strains in bloodstream infections (BSI)
    Hamed Tahmasebi, Sanaz Dehbashi, Mohammad Reza Arabestani
    Infection, Genetics and Evolution.2020; 85: 104518.     CrossRef
  • Relationship between Biofilm Regulating Operons and Various Β-Lactamase Enzymes: Analysis of the Clinical Features of Infections caused by Non-Fermentative Gram-Negative Bacilli (Nfgnb) from Iran
    Mahyar Porbaran, Reza Habibipour
    Journal of Pure and Applied Microbiology.2020; 14(3): 1723.     CrossRef
  • Carbapenem-Resistant Pseudomonas aeruginosa Strains-Distribution of the Essential Enzymatic Virulence Factors Genes
    Tomasz Bogiel, Małgorzata Prażyńska, Joanna Kwiecińska-Piróg, Agnieszka Mikucka, Eugenia Gospodarek-Komkowska
    Antibiotics.2020; 10(1): 8.     CrossRef
  • Biofilm Formation and β-lactamase Enzymes: A Synergism Activity in Acinetobacter baumannii Isolated from Wound Infection
    Mahyar Porbaran, Reza Habibipour
    Journal of Advances in Medical and Biomedical Rese.2019; 27(125): 34.     CrossRef
Anti-Human Rhinovirus 1B Activity of Dexamethasone viaGCR-Dependent Autophagy Activation
Jae-Sug Lee, Seong-Ryeol Kim, Jae-Hyoung Song, Yong-Pyo Lee, Hyun-Jeong Ko
Osong Public Health Res Perspect. 2018;9(6):334-339.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.07
  • 3,477 View
  • 60 Download
  • 4 Citations
AbstractAbstract PDF
Objectives

Human rhinoviruses (HRVs) are the major cause of the common cold. Currently there is no registered, clinically effective, antiviral chemotherapeutic agent to treat diseases caused by HRVs. In this study, the antiviral activity of dexamethasone (DEX) against HRV1B was examined.

Methods

The anti–HRV1B activity of DEX was assessed by sulforhodamine B assay in HeLa cells, and by RT-PCR in the lungs of HRV1B-infected mice. Histological evaluation of HRV1B-infected lungs was performed and a histological score was given. Anti-HRV1B activity of DEX via the glucocorticoid receptor (GCR)-dependent autophagy activation was assessed by blocking with chloroquine diphosphate salt or bafilomycin A1 treatment.

Results

In HRV1B-infected HeLa cells, treatment with DEX in a dose-dependent manner, resulted in a cell viability of > 70% indicating that HRV1B viral replication was reduced by DEX treatment. HRV1B infected mice treated with DEX, had evidence of reduced inflammation and a moderate histological score. DEX treatment showed antiviral activity against HRV1B via GCR-dependent autophagy activation.

Conclusion

This study demonstrated that DEX treatment showed anti-HRV1B activity via GCR-dependent autophagy activation in HeLa cells and HRV1B infected mice. Further investigation assessing the development of topical formulations may enable the development of improved DEX effectiveness.

Citations

Citations to this article as recorded by  
  • Intracellular translocation of HMGB1 is important for Zika virus replication in Huh7 cells
    Kim-Ling Chin, Nurhafiza Zainal, Sing-Sin Sam, Pouya Hassandarvish, Rafidah Lani, Sazaly AbuBakar
    Scientific Reports.2022;[Epub]     CrossRef
  • Pharmacological Modulators of Autophagy as a Potential Strategy for the Treatment of COVID-19
    Gustavo José da Silva Pereira, Anderson Henrique França Figueredo Leão, Adolfo Garcia Erustes, Ingrid Beatriz de Melo Morais, Talita Aparecida de Moraes Vrechi, Lucas dos Santos Zamarioli, Cássia Arruda Souza Pereira, Laís de Oliveira Marchioro, Letícia P
    International Journal of Molecular Sciences.2021; 22(8): 4067.     CrossRef
  • MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB
    Hanping Qi, Jing Ren, Lina Ba, Chao Song, Qianhui Zhang, Yonggang Cao, Pilong Shi, Bowen Fu, Yongsheng Liu, Hongli Sun
    Molecular Therapy - Nucleic Acids.2020; 19: 507.     CrossRef
  • Autophagy Augmentation to Alleviate Immune Response Dysfunction, and Resolve Respiratory and COVID-19 Exacerbations
    Garrett Pehote, Neeraj Vij
    Cells.2020; 9(9): 1952.     CrossRef
Intra-Oral Factors Influencing Halitosis in Young Women
Ho Sun Shon, Kyoung Ok Kim, Jae Kwan Jung, Eun Jong Cha, Su Ok Lee, Kyung Ah Kim
Osong Public Health Res Perspect. 2018;9(6):340-347.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.08
  • 4,145 View
  • 36 Download
  • 3 Citations
AbstractAbstract PDF
Objectives

The aim of this research was to determine intra-oral factors that affect halitosis in young women.

Methods

This study was performed between March 2014 to May 2014, and included 35 women in their 20s with good oral health. Correlation and logistic regression analyses were performed to investigate the change in halitosis immediately, and 1 hour after scaling.

Results

In both oral gas (OG) and extraoral gas (EG) groups, halitosis was reduced after scaling compared to before scaling. The logistic regression analysis of oral state factors in OG showed that as oral fluid [odds ratio (OR) = 0.792, p = 0.045] and dental plaque (OR = 0.940, p = 0.016) decreased by 1 unit, the OR in the OG group decreased (> 50). In addition, as glucose levels in the oral cavity (OR = 1.245, p = 0.075) and tongue coating index (OR = 2.912, p = 0.064) increased by 1 unit, the OR in the OG group increased (> 50). Furthermore, in the EG group, as oral fluid (OR = 0.66, p = 0.01) and dental plaque (OR = 0.95, p = 0.04) decreased, the OR in the EG group decreased (> 50) significantly.

Conclusion

To control halitosis, it is necessary to increase oral fluid and decrease the amount of tongue plaque. Furthermore, maintaining a healthy oral environment, aided by regular scaling and removal of dental plaque, may significantly control halitosis.

Citations

Citations to this article as recorded by  
  • Role of Probiotics in Halitosis of Oral Origin: A Systematic Review and Meta-Analysis of Randomized Clinical Studies
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Chemical Constituents of Essential Oils Possessing Anti-Influenza A/WS/33 Virus Activity
Hwa-Jung Choi
Osong Public Health Res Perspect. 2018;9(6):348-353.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.09
  • 18,354 View
  • 249 Download
  • 28 Citations
AbstractAbstract PDF
Objectives

This study was conducted to determine whether essential oils had anti-influenza A/WS/33 virus activity and whether there were specific compounds associated with this activity.

Methods

There were 63 essential oils evaluated for anti-influenza (A/WS/33 virus) activity using a cytopathic effect reduction method. The chemical composition of the anti-influenza essential oils was phytochemically analyzed by gas chromatography-mass spectrometry.

Results

The antiviral assays demonstrated that 11 of the 62 essential oils (100 μg/mL) possessed anti-influenza activity, reducing visible cytopathic effects of influenza A/WS/33 virus activity by > 30%. Furthermore, marjoram, clary sage and anise oils exhibited anti-influenza A/WS/33 virus activity of > 52.8%. However, oseltamivir (the anti-influenza A and B drug), showed cytotoxicity at the same concentration (100 μg/mL) as the essential oils. The chemical composition detected by GC–MS analysis, differed amongst the 3 most potent anti-viral essential oils (marjoram, clary sage and anise oils) except for linalool, which was detected in all 3 essential oils.

Conclusion

This study demonstrated anti-influenza activity in 11 essential oils tested, with marjoram, clary sage and anise essential oils being the most effective at reducing visible cytopathic effects of the A/WS/33 virus. All 3 oils contained linalool, suggesting that this may have anti-influenza activity. Further investigation is needed to characterize the antiviral activity of linalool against influenza A/WS/33 virus.

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    Valentina Noemi Madia, Walter Toscanelli, Daniela De Vita, Marta De Angelis, Antonella Messore, Davide Ialongo, Luigi Scipione, Valeria Tudino, Felicia Diodata D’Auria, Roberto Di Santo, Stefania Garzoli, Annarita Stringaro, Marisa Colone, Magda Marchetti
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Effects of Injection Laryngoplasty with Hyaluronic Acid in Patients with Vocal Fold Paralysis
Geun-Hyo Kim, Jae-Seok Lee, Chang-Yoon Lee, Yeon-Woo Lee, In-Ho Bae, Hee-June Park, Byung-Joo Lee, Soon-Bok Kwon
Osong Public Health Res Perspect. 2018;9(6):354-361.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.10
  • 3,743 View
  • 44 Download
  • 6 Citations
AbstractAbstract PDF
Objectives

The purpose of this study was to explore the effects of injection laryngoplasty (IL) with hyaluronic acid in patients with vocal fold paralysis (VFP).

Methods

A total of 50 patients with VFP participated in this study. Pre- and post-IL assessments were performed, which included analyzing the sustained vowel /a/ phonation, and the patient reading 1 Korean sentence from the “Walk” passage that comprised 25 syllables in 10 words. To investigate the effect of IL on vocal fold function, acoustic analysis (acoustic voice quality index, cepstral peak prominence, maximum phonation time, speaking fundamental frequency) was conducted and auditory-perceptual (grade and overall severity), visual judgment (gap), and self-questionnaire (voice handicap index-10) assessments were performed.

Results

The patients with VFP showed statistically significant differences between pre-and post-IL assessments for acoustic and auditory-perception, visual judgment, and self-questionnaire assessments.

Conclusion

The patients with VFP showed positive change in vocal fold function between pre- and post-IL measurements. The findings showed that IL with hyaluronic acid is an effective method to improve vocal fold function in patients with VFP.

Citations

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    A. Švejdová, J. Dršata, J. Mejzlík, M. Homoláč, J. Krtičková, J. Šatanková, V. Chrobok
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    Virgilijus Uloza, Nora Ulozaitė-Stanienė, Tadas Petrauskas, Rima Kregždytė
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    Beata Miaśkiewicz, Aleksandra Panasiewicz, Elżbieta Gos, Paulina Krasnodębska, Piotr H. Skarżyński, Agata Szkiełkowska
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Corrigendums
Corrigendum to “Epidemiological Characterization of Imported Systemic Mycoses Occurred in Korea” [Osong Public Health Res Perspect 2018;9(5):255–60]
Seung-Hak Cho, Young-Bin Yu, Je-Seop Park, Keun-Dol Yook, Young-Kwon Kim
Osong Public Health Res Perspect. 2018;9(6):362-362.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.11
  • 3,399 View
  • 31 Download
PDF
Corrigendum to “Evaluation of Potency on Diphtheria and Tetanus Toxoid for Adult Vaccines by In Vivo Toxin Neutralization Assay Using National Reference Standards”[Osong Public Health Res Perspect 2018;9(5):278–82]
Chan Woong Choi, Jae Hoon Moon, Jae Ok Kim, Si Hyung Yoo, Hyeon Guk Kim, Jung-Hwan Kim, Tae Jun Park, Sung Soon Kim
Osong Public Health Res Perspect. 2018;9(6):363-363.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.12
  • 10,865 View
  • 28 Download
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PHRP : Osong Public Health and Research Perspectives