<sec>
<b>Objectives</b>
<p>To investigate the effect of smoking upon cardiopulmonary function, maximal oxygen uptake, and obesity index, in middle-aged and older workers to propose guidelines on healthcare for these age groups.</p></sec>
<sec>
<b>Methods</b>
<p>This study analyzed medical data from 2,753 white-collar workers aged 50 years or older from workplaces located in Seoul, South Korea. Blood pressure (BP), resting heart rate, maximal oxygen uptake (VO<sub>2</sub>max), and body mass index (BMI) of each subject were measured. The collected data were analyzed using SPSS 21.0.</p></sec>
<sec>
<b>Results</b>
<p>In the smoking group BP and resting heart rate were significantly higher than in the non-smoking and smoking-cessation groups (<italic>p</italic> < 0.05). In addition, VO<sub>2</sub>max was lower in the smoking group compared to the other 2 groups. BP closely correlated with resting heart rate, abdominal fat ratio, and BMI. BMI was the highest in the group that stopped smoking and, BMI and abdominal fat ratio negatively correlated with VO<sub>2</sub>max.</p></sec>
<sec>
<b>Conclusion</b>
<p>Smoking increases the risk of cardiopulmonary disease but obesity may be caused by stopping smoking. Therefore, healthcare guidelines on smoking cessation should also include nutritional advice.</p></sec>
Citations
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Improved aerobic capacity in a randomized controlled trial of noncombustible nicotine and tobacco products Lucia Spicuzza, Francesco Pennisi, Grazia Caci, Fabio Cibella, Davide Campagna, Yusuff A. Adebisi, Claudio Saitta, Jacob George, Giulio Geraci, Riccardo Polosa Scientific Reports.2025;[Epub] CrossRef
Smoking Status on Bone Health and Osteoporosis Prevalence Vu H. Nguyen Osong Public Health and Research Perspectives.2018; 9(4): 213. CrossRef
<sec>
<b>Objectives</b>
<p>The present study was performed to determine the seroprevalence of <italic>Toxocara</italic> in children ≤ 10 years old, from rural and urban areas of Ilam.</p></sec>
<sec>
<b>Methods</b>
<p>Serum samples from 383 children ≤ 10 years old, were selected randomly from rural and urban areas of Ilam province and surveyed using enzyme-linked immunosorbent assays.</p></sec>
<sec>
<b>Results</b>
<p>The total rate of infection with <italic>Toxocara</italic> was 22% (31% with a history of contact with dogs and cats, and 14% without a history of contact). Of those infected, 23% were male and 18% were female, 36% lived a rural life and 20% had an urban life. A significant correlation was found between the incidence of disease, and urban and rural life, as well as exposure to dogs and cats. There was no correlation between prevalence and gender or age.</p></sec>
<sec>
<b>Conclusion</b>
<p>Given the high prevalence of infection with <italic>Toxocara</italic> amongst children in Ilam province, preventive work in the community such as education in risk management and periodic treatment with anti-parasitic drugs and elimination of stray dogs and cats is an appropriate measure.</p></sec>
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Maternal COVID-19 infection and the fetus: Immunological and neurological perspectives Shahab Falahi, Amir Abdoli, Azra Kenarkoohi New Microbes and New Infections.2023; 53: 101135. CrossRef
Seroprevalence of Toxocariasis and Its Associated Risk Factors among Adult Population in Kavar District, Fars Province, South of Iran: A Cross-Sectional Community-Based Seroepidemiological Survey Fatemehsadat Pezeshkian, Ali Pouryousef, Mostafa Omidian, Fattaneh Mikaeili, Ali Reza Safarpour, Sara Shojaei-Zarghani, Bahador Sarkari, Payam Behzadi Interdisciplinary Perspectives on Infectious Disea.2023; 2023: 1. CrossRef
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Seroprevalence and risk factors of Toxocara canis infection in children aged 2–15 years from the southwest Iran Masoud Foroutan, Shahrzad Soltani, Samaneh Bahadoram, Fatemeh Maghsoudi, Naser Kamyari, Shekoufe Haddadi Comparative Immunology, Microbiology and Infectiou.2022; 85: 101801. CrossRef
Seroprevalence of Toxocara spp. in children (3–13 years old) in Zahedan, Southeast of Iran Alireza Salimi Khorashad, Majid Shahraki, Mansour Rahmati Balaghaleh, Samaneh Abdolahi Khabisi, Sangeetha Rala, Reza Shafiei, Hadi Mirahmadi Journal of Parasitic Diseases.2021; 45(2): 449. CrossRef
The global prevalence of Toxocara spp. in pediatrics: a systematic review and meta-analysis Behnam Abedi, Mehran Akbari, Sahar KhodaShenas, Alireza Tabibzadeh, Ali Abedi, Reza Ghasemikhah, Marzieh Soheili, Shnoo Bayazidi, Yousef Moradi Clinical and Experimental Pediatrics.2021; 64(11): 575. CrossRef
Seroprevalence and associated risk factors of toxocariasis among nomads in Boyer-Ahmad County, southwest Iran Nasir Arefkhah, Mohammad Reza Shadzi, Fattaneh Mikaeili, Bahador Sarkari, Farideh Esfandiari, Fatemeh Goudarzi Transactions of The Royal Society of Tropical Medi.2020; 114(5): 372. CrossRef
Seroprevalence of anti-Toxocara antibody among multiple sclerosis patients: a case–control study Nastaran Khalili, Neda Khalili, Ali Nickhah, Bahman Khalili Journal of Parasitic Diseases.2020; 44(1): 145. CrossRef
Seroprevalence of toxocariasis and its related risk factors among municipal street sweepers in Shiraz District in Fars Province, southern Iran Amirhossein Erfani, Ali Pouryousef, Nasir Arefkhah, Reza Shahriarirad, Mohammad Rastegarian, Ali Zeighami, Fattaneh Mikaeili, Seyed Younes Hosseini, Bahador Sarkari Clinical Epidemiology and Global Health.2020; 8(2): 643. CrossRef
Toxocara infection: seroprevalence and associated risk factors among primary school children in central China Shuai Wang, Haoran Li, Zhijun Yao, Pengju Li, Dong Wang, Haizhu Zhang, Qing Xie, Zhenchao Zhang, Xiangrui Li Parasite.2020; 27: 30. CrossRef
Status of human toxocariasis, a neglected parasitic zoonosis in Iran: a systematic review from past to current Reza Shafiei, Mohammad T Rahimi, Reza Zolfaghari Emameh, Mehdi Mirzaei, Gregorio Perez-Cordon, Ehsan Ahmadpour Tropical Doctor.2020; 50(4): 285. CrossRef
<sec>
<b>Objectives</b>
<p>This study was designed to analyze biomarker-related publications and patent trends which biobanks could consider in planning biosample collections for biomarker research.</p></sec>
<sec>
<b>Methods</b>
<p>Publications and patents containing the term “biomarker” in the title published between 1998 to 2017 were retrieved using Scopus database and Google Patents search engine.</p></sec>
<sec>
<b>Results</b>
<p>Over the last 20 years there has been a steady increase in biomarker-related publications and patents; however this has slowed for patents over the last few years. Publications in 2017 that contained blood, serum, and plasma search terms in the abstract accounted for 50%, and serum as a search term in the title and abstract was more numerous than those containing blood, plasma, tissue, or urine. Blood-related patents were the most common patent in the last 10 years, and accounted for 110 patents in 2017. Biomarker-related publications since 2010 containing RNA and protein search terms in the title and abstract, were more numerous than those containing DNA and metabolite search terms. More than 27% of biomarker-related publications in 2017 and 21% of biomarker-related patents were associated with cancer.</p></sec>
<sec>
<b>Conclusion</b>
<p>The results of this study will help biobanks establish a biosample collection strategy for clinical application.</p></sec>
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Nanodiamond Solid-Phase Extraction and Triton X-114 Cloud Point Separation for Robust Fractionation and Shotgun Proteomics Analysis of the Human Serum Proteome Hai Lam Khuong, Chein-Hung Chen, Jung-Lee Lin, Trong-Nghia Le, Thi Hue Pham, Thi Bich Thao Le, Xuan Canh Nguyen, Van Chi Phan, Hoang Ha Chu, Wesley Wei-Wen Hsiao, Thi Minh Phuong Nguyen, Dinh Minh Pham Journal of Proteome Research.2022; 21(1): 67. CrossRef
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MicroRNA-181b Serves as a Circulating Biomarker and Regulates Inflammation in Heart Failure Hongxiao Yang, Lina Shan, Yunan Gao, Lin Li, Guifen Xu, Bin Wang, Xiaoxue Yin, Chengfang Gao, Jiaren Liu, Wei Yang, Gaetano Isola Disease Markers.2021; 2021: 1. CrossRef
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<sec>
<b>Objectives</b>
<p>Hand, Foot and Mouth disease (HFMD) is a highly contagious viral disease that affects young children and frequently causes epidemics. A vaccine is available in China (enterovirus 71) and, the Republic of Korea took the first step to develop a new vaccine. New vaccine development requires that disease burden is calculated in advance so the financial cost, morbidity and mortality can be measured.</p></sec>
<sec>
<b>Methods</b>
<p>Data from National Sentinel Surveillance and health insurance systems of 1 million claimants were used. Direct medical and non-medical costs, indirect (caregiving and premature death) costs, cases and related deaths were summarized.</p></sec>
<sec>
<b>Results</b>
<p>From 2010 to 2014, there were an estimated 3,605 to 9,271 cases of HFMD, with 1 to 3 deaths. The estimated socioeconomic disease burden ranged from 80.5 to 164.2 million USD and was similar to that of hepatitis A (93.6–103.8 million USD). Among each costs, costs of caregiving consisted of highest proportion mainly due to hiring caregivers (50% – 60%) or opportunity costs from day off (62% – 69%).</p></sec>
<sec>
<b>Conclusion</b>
<p>Considering the social impact of HFMD, the estimated socioeconomic disease burden is not high and government policies need to focus on reducing the loss of work in caregivers.</p></sec>
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How urbanization shapes the effectiveness of school closures on hand, foot, and mouth disease Yazhen Zhang, Juan Zhang, Xuefeng Zhang, Hui Jin International Journal of Infectious Diseases.2025; 154: 107845. CrossRef
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The Hand, Foot, and Mouth Disease Sentinel Surveillance System in South Korea: Retrospective Evaluation Study Bryan Inho Kim, Chiara Achangwa, Seonghui Cho, Jisoo Ahn, Jisu Won, Hyunkyung Do, Dayeong Lee, Bohye Yoon, Joohee Kim, Sukhyun Ryu JMIR Public Health and Surveillance.2024; 10: e59446. CrossRef
Association of public health and social measures on the hand-foot-mouth epidemic in South Korea Sukhyun Ryu, Changhee Han, Sheikh Taslim Ali, Chiara Achangwa, Bingyi Yang, Sen Pei Journal of Infection and Public Health.2023; 16(6): 859. CrossRef
Dynamical analysis for a reaction-diffusion HFMD model with nonsmooth saturation treatment function Lei Shi, Hongyong Zhao, Daiyong Wu Communications in Nonlinear Science and Numerical .2021; 95: 105593. CrossRef
A stage structure HFMD model with temperature-dependent latent period Hongyong Zhao, Lei Shi, Jing Wang, Kai Wang Applied Mathematical Modelling.2021; 93: 745. CrossRef
A reaction-diffusion HFMD model with nonsmooth treatment function Lei Shi, Hongyong Zhao, Daiyong Wu Advances in Difference Equations.2021;[Epub] CrossRef
Development and comparison of forecast models of hand-foot-mouth disease with meteorological factors Tao Fu, Ting Chen, Zhen-Bin Dong, Shu-Ying Luo, Ziping Miao, Xiu-Ping Song, Ru-Ting Huang, Ji-Min Sun Scientific Reports.2019;[Epub] CrossRef
Application of a combined model with seasonal autoregressive integrated moving average and support vector regression in forecasting hand-foot-mouth disease incidence in Wuhan, China Jiao-Jiao Zou, Gao-Feng Jiang, Xiao-Xu Xie, Juan Huang, Xiao-Bing Yang Medicine.2019; 98(6): e14195. CrossRef
<sec>
<b>Background</b>
<p>In patients who have suffered a stroke, the measurement of center of pressure excursion in all directions including oblique direction, anterior-medial, anterior-lateral, posterior-medial, and posterior-lateral side is important for determining balance instability but no research has been reported.</p></sec>
<sec>
<b>Objectives</b>
<p>This study investigated weight shift in all directions to determine balance instability in stroke patients, including the oblique direction, using the multi-directional functional reach test.</p></sec>
<sec>
<b>Methods</b>
<p>Eleven subjects participated. Multi-directional functional reach test consisted of moving the unaffected arm as far as possible in 8 directions. The directions were as follows; anterior, middle of anterior and lateral in unaffected side, lateral in unaffected side, and middle of the posterior and lateral in unaffected side, posterior, middle of posterior and lateral in affected side, lateral in affected side, middle of anterior and lateral in affected side.</p></sec>
<sec>
<b>Results</b>
<p>Movement was the lowest in the affected posterior-lateral side, followed by affected posterior, affected anterior-lateral, non-affected posterior lateral, affected lateral, non-affected lateral, non-affected anterior-lateral and anterior side (<italic>p</italic> < 0.05).</p></sec>
<sec>
<b>Conclusion</b>
<p>Center of pressure excursion of the affected posterior-lateral side was the most challenging for stroke patients and their reach was lowest from posterior, to lateral, and anterior directions, whilst patients could move less on the affected side compared with the non-affected side.</p></sec>
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Immediate effects of circular trunk movements on reach distance and centre of pressure distance during a multidirectional seated reach task in participants with post-stroke hemiparesis: a non-randomised controlled trial Ryohei Nabeya, Hiromi Fujii, Toshiaki Sato International Journal of Therapy and Rehabilitatio.2024; 31(1): 1. CrossRef
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<p>Murine typhus is one of the most prevalent rickettsial infections in the world, caused by the bacterial genus <italic>Rickettsia</italic>. Though the disease manifests a relatively benign clinical course with fever, rash, and headache being the 3 classic symptoms, neurological complications may arise in patients that could become permanent. In this case study, a patient with a brain abscess caused by <italic>R typhi</italic> infection is described. Based upon the recent reemergence of arthropod-borne disease, the findings in this case are significant; <italic>R typhi</italic> can cause a brain abscess that mimics a brain tumor, which delays the diagnosis and appropriate management of the disease. Murine typhus should always be considered when performing the differential diagnosis of brain abscesses in South Korea.</p>
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<p>The Japanese encephalitis (JE) vaccine was introduced to the national immunization program in 1985, which has led to a dramatic decrease in the number of reported cases, but JE continues to occur in foreign nationals residing in or traveling to Korea. Although the incidence is low, this study demonstrated that more Koreans were infected with JE than foreign-born expatriates. The incidence rates of Korean-born nationals were between 0.01 and 0.08 cases per 100,000. In contrast, the incidence rates of foreign-born nationals ranged between 0 and 0.26 cases per 100,000. The incidence rates clearly showed that foreign-born expatriates were more at risk, which underscores the importance of vaccination. We recommend heightened surveillance among JE-susceptible individuals and promote vaccination among foreign-born nationals living in Korea.</p>
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<p>The Second Meeting of the National Control Laboratories for Vaccines and Biologicals in the Western Pacific, was jointly organized by the National Institute of Food and Drug Safety Evaluation of the Ministry of Food and Drug Safety in the Republic of Korea, and by the World Health Organization Regional Office for the Western Pacific.</p>
<p>In the National Lot Release Systems session countries including Canada, China, Japan, Malaysia, Vietnam, and the Republic of Korea, all shared information on their current Lot Release Systems, including current practices and developments in risk-based official lot release of vaccines.</p>
<p>In the session on Quality Control of Blood Products, experts from the National Institute for Biological Standards and Control shared quality control and research results for; blood coagulation factor VIII products, and the measurement of procoagulant activity in immunoglobulin products. Representatives from Japan proposed a regional collaborative study to test aggregated immunoglobulin free from complement activity. A cell-based Japanese encephalitis vaccine potency assay was proposed by representatives from Korea and they also called for voluntary participation of other National Control Laboratories in a collaborative study, on the first Korean <italic>Gloydius</italic> anti-venom standard. Participants agreed in general to continue communicating, and coordinate presentation of the study results.</p>
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