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Volume 13(5); October 2022
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Editorial
What measures should be considered in this 2022-2023 winter season
Jong-Koo Lee
Osong Public Health Res Perspect. 2022;13(5):313-315.   Published online October 28, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0286
  • 1,945 View
  • 60 Download
PDF
Review Articles
India’s efforts to achieve 1.5 billion COVID-19 vaccinations: a narrative review
Kapil Singh, Ashwani Verma, Monisha Lakshminarayan
Osong Public Health Res Perspect. 2022;13(5):316-327.   Published online October 14, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0104
  • 6,050 View
  • 112 Download
  • 9 Web of Science
  • 13 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
The initial case of coronavirus disease 2019 (COVID-19) in India was reported on January 30, 2020, and subsequently, the number of COVID-19-infected patients surged during the first wave of April 2020 and the second wave in the same month of 2021. The government of India imposed a strict nationwide lockdown in April 2020 and extended it until May 2020. The second wave of COVID-19 in India overwhelmed the country’s health facilities and exhausted its medical and paramedical workforce. This narrative review was conducted with the aim of summarizing the evidence drawn from policy documents of governmental and non-governmental organizations, as well as capturing India's COVID-19 vaccination efforts. The findings from this review cover the Indian government's vaccination initiatives, which ranged from steps taken to combat vaccine hesitancy to vaccination roadmaps, deployment plans, the use of digital health technology, vaccination monitoring, adverse effects, and innovative strategies such as Har Ghar Dastak and Jan Bhagidari Andolan (people’s participation). These efforts collectively culminated in the successful administration of more than 1.8 billion doses of COVID-19 vaccines in India. This review also provides insights into other countries’ responses to COVID-19 and guidance for future pandemics.

Citations

Citations to this article as recorded by  
  • Developments and Trends of Immunization in India: A Narrative Review
    Pratik P Tawde, Zahiruddin Quazi, Abhay Gaidhane, Sonali G Choudhari
    Cureus.2024;[Epub]     CrossRef
  • Digital health technology used in emergency large-scale vaccination campaigns in low- and middle-income countries: a narrative review for improved pandemic preparedness
    Paula Mc Kenna, Lindsay A. Broadfield, Annik Willems, Serge Masyn, Theresa Pattery, Ruxandra Draghia-Akli
    Expert Review of Vaccines.2023; 22(1): 243.     CrossRef
  • Media Reporting Relating to COVID-19 Vaccination as a Driver of Vaccine Hesitancy Prior to the Second Wave of the COVID-19 Pandemic in India: A Content Analysis of Newspaper and Digital Media Reports
    Saurav Basu, Himanshi Sharma
    Cureus.2023;[Epub]     CrossRef
  • An assessment of the strategy and status of COVID-19 vaccination in India
    Sneh Lata Gupta, Surbhi Goswami, Ananya Anand, Namrata Naman, Priya Kumari, Priyanka Sharma, Rishi K. Jaiswal
    Immunologic Research.2023; 71(4): 565.     CrossRef
  • Development of a Choice-framework for Covid vaccines in India using a multi-criteria decision analysis approach
    Tarun K. George, Nayana P. Nair, Awnish Kumar Singh, A. Dilesh Kumar, Arup Deb Roy, Varshini Neethi Mohan, Gagandeep Kang
    Vaccine.2023; 41(25): 3755.     CrossRef
  • COVID-19 Booster Dose Coverage and Hesitancy among Older Adults in an Urban Slum and Resettlement Colony in Delhi, India
    Nandini Sharma, Saurav Basu, Heena Lalwani, Shivani Rao, Mansi Malik, Sandeep Garg, Rahul Shrivastava, Mongjam Meghachandra Singh
    Vaccines.2023; 11(7): 1177.     CrossRef
  • Review of the unmet medical need for vaccination in adults with immunocompromising conditions: An Indian perspective
    Ashok Vaid, Neha Rastogi, T. Mark Doherty, Peter San Martin, Yashpal Chugh
    Human Vaccines & Immunotherapeutics.2023;[Epub]     CrossRef
  • Translating the COVID-19 experience in widening the HPV vaccination campaign for cervical cancer in India
    Aruni Ghose, Anisha Agarwal, Bhawna Sirohi, Shona Nag, Linus Chuang, Swarupa Mitra
    Gynecologic Oncology Reports.2023; 48: 101247.     CrossRef
  • Symptomatic prevalence of covid-19 in vaccinated and non-vaccinated population
    Jay Bhupesh Pandya, Nirali Milind Shethia, Divya Bangera, Shailaja Gada Saxena
    IP International Journal of Medical Microbiology a.2023; 9(2): 110.     CrossRef
  • Active surveillance of adverse events following COVID-19 vaccines in a tertiary care hospital
    Naveena Mary Cherian, Dravya Anna Durai, Muhammed Jaisel, Divyansh Sharma, Juny Sebastian, Chetak Kadabasal Basavaraja, Merrin Mathew
    Therapeutic Advances in Vaccines and Immunotherapy.2023;[Epub]     CrossRef
  • Effectiveness of ayurvedic formulation, NAOQ19 along with standard care in the treatment of mild-moderate COVID-19 patients: A double blind, randomized, placebo-controlled, multicentric trial
    Pankaj Bhardwaj, Kalaiselvan Ganapathy, Monika Pathania, K.H. Naveen, Jaykaran Charan, Siddhartha Dutta, Ravisekhar Gadepalli, Srikanth Srinivasan, Manoj Kumar Gupta, Akhil D. Goel, Naresh Midha, Bharat Kumar, Meenakshi Sharma, Praveen Sharma, Mithu Baner
    Journal of Ayurveda and Integrative Medicine.2023; 14(6): 100778.     CrossRef
  • Balancing Routine and Pandemic: The Synergy of India’s Universal Immunization Program and COVID-19 Vaccination Program
    Pawan Kumar, Ashish Birendra Chakraborty, Suhas Dhandore, Pritu Dhalaria, Ajeet Kumar Singh, Disha Agarwal, Kapil Singh, Pretty Priyadarshini, Paras Jain, Vidushi Bahl, Gunjan Taneja
    Vaccines.2023; 11(12): 1776.     CrossRef
  • Unveiling vaccine safety: a narrative review of pharmacovigilance in India's COVID-19 vaccination
    Megha Hegde, Saurav Raj, Dhananjay Tikadar, Sanatkumar B Nyamagoud
    Monaldi Archives for Chest Disease.2023;[Epub]     CrossRef
Effects of medication adherence interventions for older adults with chronic illnesses: a systematic review and meta-analysis
Hae Ok Jeon, Myung-Ock Chae, Ahrin Kim
Osong Public Health Res Perspect. 2022;13(5):328-340.   Published online October 12, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0168
  • 5,467 View
  • 230 Download
  • 3 Web of Science
  • 3 Crossref
AbstractAbstract PDF
This systematic review and meta-analysis aimed to understand the characteristics of medication adherence interventions for older adults with chronic illnesses, and to investigate the average effect size by combining the individual effects of these interventions. Data from studies meeting the inclusion criteria were systematically collected in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The results showed that the average effect size (Hedges’ g) of the finally selected medication adherence interventions for older adults with chronic illnesses calculated using a random-effects model was 0.500 (95% confidence interval [CI], 0.342−0.659). Of the medication adherence interventions, an implementation intention intervention (using face-to-face meetings and telephone monitoring with personalized behavioral strategies) and a health belief model–based educational program were found to be highly effective. Face-to-face counseling was a significantly effective method of implementing medication adherence interventions for older adults with chronic illnesses (Hedges’ g=0.531, 95% CI, 0.186−0.877), while medication adherence interventions through education and telehealth counseling were not effective. This study verified the effectiveness of personalized behavioral change strategies and cognitive behavioral therapy based on the health belief model, as well as face-to-face meetings, as medication adherence interventions for older adults with chronic illnesses.

Citations

Citations to this article as recorded by  
  • Health Behavior Change to Mitigate Dementia Risk: An Updated Review
    Victoria Sanborn, Jennifer D. Davis, Laura E. Korthauer
    Current Geriatrics Reports.2024; 13(3): 162.     CrossRef
  • Relationship Between Depression and Medication Adherence Among Chronic Disease Patients in the Middle East
    Abdulrahman O Alomar, Rakan H Khushaim, Shahad K Al-Ghanem, Abeer T Bin Jumaiah, Suhail M Albaqami, Lujain A Alleft, Eman A Abahussain
    Cureus.2024;[Epub]     CrossRef
  • Development and Preliminary Psychometric Testing of a Brief Tool to Measure Medication Adherence in Older Populations
    Paolo Iovino, Paola Obbia, Vincenzo De Luca, Clara Donnoli, Lola Patumi, Lisa Leonardini, Ernesto Palummeri, Manuela Ruatta, Anna Basso, Yari Longobucco, Laura Rasero, Giuseppe Liotta, Maddalena Illario
    Clinical Interventions in Aging.2024; Volume 19: 1765.     CrossRef
Zika virus as an emerging arbovirus of international public health concern
Samira Vaziri, Siavash Hamzeh Pour, Fateme Akrami-Mohajeri
Osong Public Health Res Perspect. 2022;13(5):341-351.   Published online October 12, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0101
  • 3,471 View
  • 149 Download
  • 5 Web of Science
  • 6 Crossref
AbstractAbstract PDF
Zika virus (ZIKV) was identified in 1947 in a rhesus monkey during an investigation of the yellow fever virus in the Zika Forest of Uganda; it was also isolated later from humans in Nigeria. The main distribution areas of ZIKV were the African mainland and South-East Asia in the 1980s, Micronesia in 2007, and more recently the Americas in 2014. ZIKV belongs to the Flaviviridae family and Flavivirus genus. ZIKV infection, which is transmitted by Aedes mosquitoes, is an emerging arbovirus disease. The clinical symptoms of ZIKV infection are fever, headache, rashes, arthralgia, and conjunctivitis, which clinically resemble dengue fever syndrome. Sometimes, ZIKV infection has been associated with Guillain-Barré syndrome and microcephaly. At the end of 2015, following an increase in cases of ZIKV infection associated with Guillain-Barré syndrome and microcephaly in newborns in Brazil, the World Health Organization declared a global emergency. Therefore, considering the global distribution and pathogenic nature of this virus, the current study aimed at reviewing the virologic features, transmission patterns, clinical manifestations, diagnosis, treatment, and prevention of ZIKV infection.

Citations

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  • A Review on The Pathogenesis of Cardiovascular Disease of Flaviviridea Viruses Infection
    Tie-Hua Yang, Wen-Cong Gao, Xin Ma, Qian Liu, Pan-Pan Pang, Yong-Tang Zheng, Yinnong Jia, Chang-Bo Zheng
    Viruses.2024; 16(3): 365.     CrossRef
  • The race against time: Zika virus on the horizon in Pakistan
    Moiz Ahmed Khan, Summaiya Zafar
    Tropical Doctor.2024; 54(3): 231.     CrossRef
  • Zika’s resurgence in Thailand: a 300% surge demands urgent action
    Shriyansh Srivastava, Sachin Kumar, Nandani Jayaswal, Rachana Mehta, Prakasini Satapathy, Aroop Mohanty, Ranjit Sah
    International Journal of Surgery Open.2024; 62(2): 180.     CrossRef
  • Zika virus tropism and pathogenesis: understanding clinical impacts and transmission dynamics
    Saeed Tajik, Ali Vasheghani Farahani, Omid Salahi Ardekani, Saba Seyedi, Zahra Tayebi, Mostafa Kami, Faezeh Aghaei, Tahmine Mohammad Hosseini, Mohammad Mahdi Khosravi Nia, Roben Soheili, Arash Letafati
    Virology Journal.2024;[Epub]     CrossRef
  • Predição de casos de arboviroses no Recife utilizando computação de reservatório
    Ana Clara Gomes Da Silva, Cláudia Priscila Nunes Silva, Clarisse Lins De Lima, Danilo Wanderley Lapa, Felipe Estevão Da Silva, Mariana Marinho da Silva Andrade, Arianne Sarmento Torcate, Cecília Cordeiro Da Silva, Giselle Machado Magalhães Moreno, Welling
    Journal of Health Informatics.2024;[Epub]     CrossRef
  • Zika virus disease: an alarming situation resurfacing on the radar – a short communication
    Sanobar Shariff, Burhan Kantawala, Nakyanzi Hamiidah, Tularam Yadav, Abubakar Nazir, Olivier Uwishema
    Annals of Medicine & Surgery.2023; 85(10): 5294.     CrossRef
Original Articles
A case-control study of acute hepatitis A in South Korea, 2019
Jung Hee Hyun, Ju Young Yoon, Sang Hyuk Lee
Osong Public Health Res Perspect. 2022;13(5):352-359.   Published online October 12, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0141
  • 4,050 View
  • 137 Download
  • 2 Web of Science
  • 4 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Objectives
We aimed to reconfirm the source of hepatitis A virus (HAV) infection through epidemiological and genotype investigations of individual cases in a 2019 outbreak in South Korea. Methods: We investigated food intake histories, associations with hepatitis A, and genotypes of HAV in 31 patients with hepatitis aged 20 to 49 years registered in the integrated disease and health management system during December 1–7, 2019 (case group) and in 35 sex- and agematched people without a history of HAV vaccination or infection among patients’ families and colleagues (control group). Results: The consumption of salted clams was a significant factor (odds ratio, 4.33; 95% confidence interval, 1.32–14.18) in the risk factor analysis of food intake history. HAV genotypes were analyzed in 24 of 31 patients. Type IA and type IIIA were found in 23 and 1 cases, respectively. Conclusion: Salted clams are considered to have been the source of HAV infection at 49 weeks of the HAV outbreak in 2019; this result was consistent with that of a previous epidemiological investigation conducted by the Korea Disease Control and Prevention Agency in September 2019. Therefore, monitoring of the production and distribution of salted clams needs to be continued.

Citations

Citations to this article as recorded by  
  • Monitoring viruses and beta-lactam resistance genes through wastewater surveillance during a COVID-19 surge in Suwon, South Korea
    Rajendra Singh, Jaewon Ryu, Sung Soo Park, Sungpyo Kim, Keugtae Kim
    Science of The Total Environment.2024; 922: 171223.     CrossRef
  • Prevalence of foodborne viruses and influenza A virus from poultry processing plants to retailed chickens
    Daseul Yeo, Mengxiao Song, Md. Iqbal Hossain, Soontag Jung, Zhaoqi Wang, Dong Joo Seo, Min Suk Rhee, Changsun Choi
    Frontiers in Sustainable Food Systems.2023;[Epub]     CrossRef
  • A Study on the Detection Rate of Hepatitis A from Gastroenteritis Patients and the Genotype Analysis of Hepatitis A Virus in Busan
    Sun Hee Park, Chanhee Kim, Summi Lee, Jihye Jeong, Junghye Choi, Seung Ju Lee
    Journal of Bacteriology and Virology.2023; 53(2): 74.     CrossRef
  • A Study on the Detection Rate of Hepatitis A from Gastroenteritis Patients and the Genotype Analysis of Hepatitis A Virus in Busan
    Sun Hee Park, Chanhee Kim, Summi Lee, Jihye Jeong, Junghye Choi, Seung Ju Lee
    Journal of Bacteriology and Virology.2023; 53(2): 74.     CrossRef
Investigation of SARS-CoV-2 lineages and mutations circulating in a university-affiliated hospital in South Korea analyzed using Oxford Nanopore MinION sequencing
Hyaekang Kim, Sung Hee Chung, Hyun Soo Kim, Han-Sung Kim, Wonkeun Song, Ki Ho Hong, Jae-Seok Kim
Osong Public Health Res Perspect. 2022;13(5):360-369.   Published online October 11, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0183
  • 4,099 View
  • 84 Download
  • 2 Web of Science
  • 2 Crossref
AbstractAbstract PDFSupplementary Material
Objectives
Despite the introduction of vaccines, treatments, and massive diagnostic testing, the evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has continued to overcome barriers that had slowed its previous spread. As the virus evolves towards increasing fitness, it is critical to continue monitoring the occurrence of new mutations that could evade human efforts to control them. Methods: We performed whole-genome sequencing using Oxford Nanopore MinION sequencing on 58 SARS-CoV-2 isolates collected during the ongoing coronavirus disease 2019 pandemic at a tertiary hospital in South Korea and tracked the emergence of mutations responsible for massive spikes in South Korea. Results: The differences among lineages were more pronounced in the spike gene, especially in the receptor-binding domain (RBD), than in other genes. Those RBD mutations could compromise neutralization by antibodies elicited by vaccination or previous infections. We also reported multiple incidences of Omicron variants carrying mutations that could impair the diagnostic sensitivity of reverse transcription-polymerase chain reaction-based testing. Conclusion: These results provide an understanding of the temporal changes of variants and mutations that have been circulating in South Korea and their potential impacts on antigenicity, therapeutics, and diagnostic escape of the virus. We also showed that the utilization of the nanopore sequencing platform and the ARTIC workf low can provide convenient and accurate SARS-CoV-2 genomic surveillance even at a single hospital.

Citations

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  • Understanding large scale sequencing datasets through changes to protein folding
    David Shorthouse, Harris Lister, Gemma S Freeman, Benjamin A Hall
    Briefings in Functional Genomics.2024; 23(5): 517.     CrossRef
  • Molecular epidemiology of SARS‐CoV‐2 in Mongolia, first experience with nanopore sequencing in lower‐ and middle‐income countries setting
    Munkhtuya Erendereg, Suvd Tumurbaatar, Otgonjargal Byambaa, Gerelmaa Enebish, Natsagdorj Burged, Tungalag Khurelsukh, Nomin‐Erdene Baatar, Badmaarag Munkhjin, Jargaltulga Ulziijargal, Anuujin Gantumur, Oyunbaatar Altanbayar, Ochbadrakh Batjargal, Delgermu
    Immunity, Inflammation and Disease.2023;[Epub]     CrossRef
Clinical outcomes of remdesivir-treated COVID-19 patients in South Korea
Mi Yu, Bryan Inho Kim, Jungyeon Kim, Jin Gwack
Osong Public Health Res Perspect. 2022;13(5):370-376.   Published online October 18, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0138
  • 2,750 View
  • 77 Download
  • 2 Web of Science
  • 2 Crossref
AbstractAbstract PDF
Objectives
This study analyzed the clinical outcomes of remdesivir treatment in coronavirus disease 2019 (COVID-19) patients in South Korea.
Methods
This retrospective cohort study involved the secondary analysis of epidemiological data. Among patients diagnosed with COVID-19 from July 2, 2020 to March 23, 2021 (12 AM), 4,868 who received oxygen therapy and were released from isolation after receiving remdesivir treatment were assigned to the treatment group, and 6,068 patients who received oxygen therapy but not remdesivir were assigned to the untreated group. The study subjects included children under the age of 19. The general characteristics and severity were compared between the groups. Differences in the time to death and mortality were also compared.
Results
In the untreated group, the hazard ratio [HR] for mortality was 1.59 among patients aged ≥70 years and 2.32 in patients with severe disease in comparison to the treatment group. In a comparison of survival time among patients with severe disease aged ≥70 years, the HR for mortality before 50 days was 2.09 in the untreated group compared to the treatment group.
Conclusion
Patients with remdesivir treatment showed better clinical outcomes in this study, but these results should be interpreted with caution since this study was not a fully controlled clinical trial.

Citations

Citations to this article as recorded by  
  • The Role of Multidimensional Prognostic Index to Identify Hospitalized Older Adults with COVID-19 Who Can Benefit from Remdesivir Treatment: An Observational, Prospective, Multicenter Study
    Carlo Custodero, Nicola Veronese, Eva Topinkova, Helena Michalkova, Maria Cristina Polidori, Alberto Cella, Alfonso J. Cruz-Jentoft, Christine A. F. von Arnim, Margherita Azzini, Heidi Gruner, Alberto Castagna, Giovanni Cenderello, Romina Custureri, Tania
    Drugs & Aging.2023; 40(7): 643.     CrossRef
  • Remdesivir: A Review in COVID-19
    Hannah A. Blair
    Drugs.2023; 83(13): 1215.     CrossRef
Brief Reports
Presumed population immunity to SARS-CoV-2 in South Korea, April 2022
Eun Jung Jang, Young June Choe, Seung Ah Choe, Yoo-Yeon Kim, Ryu Kyung Kim, Jia Kim, Do Sang Lim, Ju Hee Lee, Seonju Yi, Sangwon Lee, Young-Joon Park
Osong Public Health Res Perspect. 2022;13(5):377-381.   Published online October 14, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0209
  • 3,097 View
  • 78 Download
  • 3 Web of Science
  • 4 Crossref
Graphical AbstractGraphical Abstract AbstractAbstract PDF
Objectives
We estimated the overall and age-specific percentages of the Korean population with presumed immunity against severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) as of April 2022 using the national registry.
Methods
We used the national coronavirus disease 2019 (COVID-19) infection and vaccination registry from South Korea, as described to define individuals with a previous history of COVID-19 infection, vaccination, or both, as persons with presumed immunity.
Results
Of a total of 53,304,627 observed persons, 24.4% had vaccination and infection, 58.1% had vaccination and no infection, 7.6% had infection and no vaccination, and 9.9% had no immunity. The SARS-CoV-2 Omicron variant emerged at a time when the presumed population immunity ranged from 80% to 85%; however, nearly half of the children were presumed to have no immunity.
Conclusion
We report a gap in population immunity, with lower presumed protection in children than in adults. The approach presented in this work can provide valuable informed tools to assist vaccine policy-making at a national level.

Citations

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  • Realistic Estimation of COVID-19 Infection by Seroprevalence Surveillance of SARS-CoV-2 Antibodies: An Experience From Korea Metropolitan Area From January to May 2022
    In Hwa Jeong, Jong-Hun Kim, Min-Jung Kwon, Jayoung Kim, Hee Jin Huh, Byoungguk Kim, Junewoo Lee, Jeong-hyun Nam, Eun-Suk Kang
    Journal of Korean Medical Science.2024;[Epub]     CrossRef
  • Epidemiology of Coronavirus Disease 2019 in Infants and Toddlers, Seoul, South Korea
    JiWoo Sim, Euncheol Son, Young June Choe
    Pediatric Infection & Vaccine.2024; 31(1): 94.     CrossRef
  • Predicting adherence to COVID-19 preventive measures among South Korean adults aged 40 to 69 Years using the expanded health empowerment model
    Su-Jung Nam, Tae-Young Pak
    SSM - Population Health.2023; 22: 101411.     CrossRef
  • Acute COVID-19 in unvaccinated children without a history of previous infection during the delta and omicron periods
    Jee Min Kim, Ji Yoon Han, Seung Beom Han
    Postgraduate Medicine.2023; 135(7): 727.     CrossRef
Adverse events of the Pfizer-BioNTech COVID-19 vaccine in Korean children and adolescents aged 5 to 17 years
Seontae Kim, Yeseul Heo, Soon-Young Seo, Do Sang Lim, Enhi Cho, Yeon-Kyeng Lee
Osong Public Health Res Perspect. 2022;13(5):382-390.   Published online October 14, 2022
DOI: https://doi.org/10.24171/j.phrp.2022.0233
  • 3,197 View
  • 125 Download
  • 2 Web of Science
  • 4 Crossref
AbstractAbstract PDF
Objectives
This study aimed to identify potential safety signals and adverse events following the primary Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccination series among children and adolescents aged 5 to 17 years in the Republic of Korea. Methods: Adverse events reported through the COVID-19 vaccination management system (CVMS, a web-based passive vaccine safety surveillance system) and adverse events and health conditions collected from a text message-based survey were analyzed. Results: A total of 14,786 adverse events among 5 to 17-year-old children and adolescents were reported in the CVMS; 14,334 (96.9%) were non-serious and 452 (3.1%) were serious, including 125 suspected cases of acute cardiovascular injury and 101 suspected cases of anaphylaxis. The overall reporting rate was lower in 5 to 11-year-old children (64.5 per 100,000 doses) than in 12 to 17-year-old adolescents (300.5 per 100,000 doses). The text message survey identified that local and systemic adverse events after either dose were reported less frequently in 5 to 11-year-old children than in 12 to 17-year-old adolescents (p<0.001). The most commonly reported adverse events were pain at the injection site, myalgia, headache, and fatigue/tiredness. Conclusion: The overall results are consistent with the results of controlled trials; serious adverse events were extremely rare among 5 to 17-year-old children and adolescents following Pfizer-BioNTech COVID-19 vaccination. Adverse events were less frequent in children aged 5 to 11 years than in adolescents aged 12 to 17 years.

Citations

Citations to this article as recorded by  
  • The descriptive epidemiology of adverse events following two doses of mRNA COVID-19 vaccination in Curaçao, the Caribbean
    Jonathan Lambo, Sirving Keli, Shaheen Khan Kaplan, Temiloluwa Njideaka-Kevin, Sireesha Bala Arja, Alaa Khedir Omer Altahir, Itunu Olonade, Rohit Kumar
    Infectious Diseases.2024; : 1.     CrossRef
  • Myocarditis and Pericarditis are Temporally Associated with BNT162b2 COVID-19 Vaccine in Adolescents: A Systematic Review and Meta-analysis
    Yongyeon Choi, Jue Seong Lee, Young June Choe, Hyeran Lee, Yoonsun Yoon, Seung Hwan Shin, Myung-Jae Hwang, HyoSug Choi, Sara Na, Jong Hee Kim, Hyun Mi Kang, Bin Ahn, Kyoungsan Seo, Sangshin Park
    Pediatric Cardiology.2024;[Epub]     CrossRef
  • Safety monitoring of COVID-19 vaccines: February 26, 2021, To June 4, 2022, Republic of Korea
    Yeon-Kyeng Lee, Yunhyung Kwon, Yesul Heo, Eun Kyoung Kim, Seung Yun Kim, Hoon Cho, Seontae Kim, Mijeong Ko, Dosang Lim, Soon-Young Seo, Enhi Cho
    Clinical and Experimental Pediatrics.2023; 66(10): 415.     CrossRef
  • Effectiveness of the BNT162b2 vaccine in preventing morbidity and mortality associated with COVID-19 in children aged 5 to 11 years: A systematic review and meta-analysis
    Sumayyah Ebrahim, Ntombifuthi Blose, Natasha Gloeck, Ameer Hohlfeld, Yusentha Balakrishna, Rudzani Muloiwa, Andy Gray, Andy Parrish, Karen Cohen, Ruth Lancaster, Tamara Kredo, Julia Robinson
    PLOS Global Public Health.2023; 3(12): e0002676.     CrossRef

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