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Young-ju Choi 1 Article
Epidemiological Study on Candida Species in Patients with Cancer in the Intensive Care Unit
Young-ju Choi, Byeongyeo Lee, Sun-A Park
Osong Public Health Res Perspect. 2017;8(6):384-388.   Published online December 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.6.05
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  • 1 Citations
AbstractAbstract PDF
Objectives

Although cancer survival rates have increased, serious infection complications can arise in cancer patients. Candida can occur in various tissues and has significant effects on the prognosis of patients with cancer. Thus, we conducted an epidemiological study on Candida infections in patients with cancer admitted to the intensive care unit.

Methods

A retrospective study was conducted in adult patients with cancer admitted to the intensive care unit between January 1, 2013, and December 31, 2015. Candida infection status and predictive factors for mortality were examined in 634 patients.

Results

The predictive factors for mortality included the use of steroids, use of a central venous catheter or mechanical ventilator, and identification of Candida in the blood. Patients who stayed in the surgical and intensive care unit for more than 7 days had a lower risk of death than that in those with shorter days.

Conclusion

The present study shows that invasive procedures, bloodstream infections, and the use of steroids increase the risk of mortality in Candida-infected patients with cancer. To improve the quality of life and reduce mortality, further studies are needed on the factors affecting the risk of mortality associated with Candida infection.

Citations

Citations to this article as recorded by  
  • Ionic Liquids with Anti-Candida and Anticancer Dual Activity as Potential N-Myristoyltransferase Inhibitors
    Larysa Metelytsia, Maria Trush, Ivan Semenyuta, Sergiy Rogalsky, Oleksandr Kobzar, Larisa Kalashnikova, Volodymyr Blagodatny, Diana Hodyna
    Current Bioactive Compounds.2020; 16(7): 1036.     CrossRef

PHRP : Osong Public Health and Research Perspectives