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Yeon-Woo Lee 1 Article
Effects of Injection Laryngoplasty with Hyaluronic Acid in Patients with Vocal Fold Paralysis
Geun-Hyo Kim, Jae-Seok Lee, Chang-Yoon Lee, Yeon-Woo Lee, In-Ho Bae, Hee-June Park, Byung-Joo Lee, Soon-Bok Kwon
Osong Public Health Res Perspect. 2018;9(6):354-361.   Published online December 31, 2018
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AbstractAbstract PDF

The purpose of this study was to explore the effects of injection laryngoplasty (IL) with hyaluronic acid in patients with vocal fold paralysis (VFP).


A total of 50 patients with VFP participated in this study. Pre- and post-IL assessments were performed, which included analyzing the sustained vowel /a/ phonation, and the patient reading 1 Korean sentence from the “Walk” passage that comprised 25 syllables in 10 words. To investigate the effect of IL on vocal fold function, acoustic analysis (acoustic voice quality index, cepstral peak prominence, maximum phonation time, speaking fundamental frequency) was conducted and auditory-perceptual (grade and overall severity), visual judgment (gap), and self-questionnaire (voice handicap index-10) assessments were performed.


The patients with VFP showed statistically significant differences between pre-and post-IL assessments for acoustic and auditory-perception, visual judgment, and self-questionnaire assessments.


The patients with VFP showed positive change in vocal fold function between pre- and post-IL measurements. The findings showed that IL with hyaluronic acid is an effective method to improve vocal fold function in patients with VFP.


Citations to this article as recorded by  
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  • Efficacy of Injectable Laryngoplasty With Hyaluronic Acid and/or Calcium Hydroxyapatite in the Treatment of Glottic Incompetence. Systematic Review and Meta-analysis
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    Journal of Voice.2023;[Epub]     CrossRef
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    M. Goncalves, J. Taeger, S. Hackenberg
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  • Meta-Analysis on the Validity of the Acoustic Voice Quality Index
    Christina Batthyany, Ben Barsties V. Latoszek, Youri Maryn
    Journal of Voice.2022;[Epub]     CrossRef
  • Injection laryngoplasty with hyaluronic acid for glottal insufficiency in unilateral vocal fold paralysis: a systematic review of the literature
    A. Švejdová, J. Dršata, J. Mejzlík, M. Homoláč, J. Krtičková, J. Šatanková, V. Chrobok
    European Archives of Oto-Rhino-Laryngology.2022; 279(11): 5071.     CrossRef
  • Can preoperative results predict the need for future reintervention following injection laryngoplasty for unilateral vocal fold paralysis?
    Beata Miaśkiewicz, Aleksandra Panasiewicz, Elżbieta Gos, Paulina Krasnodębska, Piotr H. Skarżyński, Agata Szkiełkowska
    European Archives of Oto-Rhino-Laryngology.2021; 278(10): 3883.     CrossRef

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