- Epidemiological, imaging, laboratory, and clinical characteristics and factors related to mortality in patients with COVID-19: a single-center study
-
Zohreh Azarkar, Hamid Salehiniya, Toba Kazemi, Hamid Abbaszadeh
-
Osong Public Health Res Perspect. 2021;12(3):169-176. Published online May 26, 2021
-
DOI: https://doi.org/10.24171/j.phrp.2021.0012
-
-
6,349
View
-
128
Download
-
8
Web of Science
-
8
Crossref
-
Abstract
PDF
- Objectives
Coronavirus disease 2019 (COVID-19) is a novel pandemic. Considerable differences in disease severity and the mortality rate have been observed in different parts of the world. The present study investigated the characteristics and outcomes of patients hospitalized with COVID-19 in Iran.
Methods
We established a retrospective cohort to study hospitalized COVID-19 patients in Iran. Epidemiological, imaging, laboratory, and clinical characteristics and outcomes were recorded from medical documents. The chi-square test, t-test, and logistic regression models were used to analyze the data. A p<0.05 was considered to indicate statistical significance.
Results
In total, 364 cases (207 males and 157 females) were analyzed. The most common symptoms were cough, fever, and dyspnea. Multifocal bilateral ground-glass opacities with peripheral distribution were the predominant imaging finding. The mean age of patients was 54.28±18.81 years. The mean age of patients who died was 71.50±14.60 years. The mortality rate was 17.6%. The total proportion of patients with a comorbidity was 47.5%, and 84.4% of patients who died had a comorbidity. Sex, history of diabetes mellitus, and dyslipidemia were not significantly associated with mortality (p>0.05). However, mortality showed significant relationships with body mass index; age; history of hypertension, chronic kidney disease (CKD), ischemic heart disease, cerebrovascular accident (CVA), pulmonary disease, and cancer; and abnormal high-resolution computed tomography (HRCT) findings (p<0.05 for all). Cancer had the highest odds ratio.
Conclusion
Comorbidities (especially cancer, CKD, and CVA), severe obesity, old age, and abnormal HRCT findings affected the health outcomes of patients hospitalized with COVID-19.
-
Citations
Citations to this article as recorded by
- Obesity as a Risk Factor for Complications and Mortality in Individuals with SARS-CoV-2: A Systematic Review
Marielle Priscila de Paula Silva-Lalucci, Déborah Cristina de Souza Marques, Pablo Valdés-Badilla, Leonardo Vidal Andreato, Braulio Henrique Magnani Branco Nutrients.2024; 16(4): 543. CrossRef - Effects of SARS-CoV-2 infections in patients with cancer on mortality, ICU admission and incidence: a systematic review with meta-analysis involving 709,908 participants and 31,732 cancer patients
Mehmet Emin Arayici, Nazlican Kipcak, Ufuktan Kayacik, Cansu Kelbat, Deniz Keskin, Muhammed Emin Kilicarslan, Ahmet Veli Kilinc, Sumeyye Kirgoz, Anil Kirilmaz, Melih Alihan Kizilkaya, Irem Gaye Kizmaz, Enes Berkin Kocak, Enver Kochan, Begum Kocpinar, Fatm Journal of Cancer Research and Clinical Oncology.2023; 149(7): 2915. CrossRef - Risk Factors Associated with Severity and Death from COVID-19 in Iran: A Systematic Review and Meta-Analysis Study
Ahmad Mehri, Sahar Sotoodeh Ghorbani, Kosar Farhadi-Babadi, Elham Rahimi, Zahra Barati, Niloufar Taherpour, Neda Izadi, Fatemeh Shahbazi, Yaser Mokhayeri, Arash Seifi, Saeid Fallah, Rezvan Feyzi, Koorosh Etemed, Seyed Saeed Hashemi Nazari Journal of Intensive Care Medicine.2023; 38(9): 825. CrossRef - The association between stroke and COVID-19-related mortality: a systematic review and meta-analysis based on adjusted effect estimates
Shuwen Li, Jiahao Ren, Hongjie Hou, Xueya Han, Jie Xu, Guangcai Duan, Yadong Wang, Haiyan Yang Neurological Sciences.2022; 43(7): 4049. CrossRef - Mental health status of dentists during COVID‐19 pandemic: A systematic review and meta‐analysis
Hamid Salehiniya, Sare Hatamian, Hamid Abbaszadeh Health Science Reports.2022;[Epub] CrossRef - Laboratory biomarker predictors for disease progression and outcome among Egyptian COVID-19 patients
Lamiaa A Fathalla, Lamyaa M Kamal, Omina Salaheldin, Mahmoud A Khalil, Mahmoud M Kamel, Hagar H Fahim, Youssef AS Abdel-Moneim, Jawaher A Abdulhakim, Ahmed S Abdel-Moneim, Yomna M El-Meligui International Journal of Immunopathology and Pharm.2022;[Epub] CrossRef - Obesity and Infection: What Have We Learned From the COVID-19 Pandemic
Emilia Vassilopoulou, Roxana Silvia Bumbacea, Aikaterini Konstantina Pappa, Athanasios N. Papadopoulos, Dragos Bumbacea Frontiers in Nutrition.2022;[Epub] CrossRef - Mental health of the people of northern Iran during the quarantine time of 2020 following the coronavirus epidemic
Fereshteh Araghian Mojarad, Mohammad Ali Heidari Gorji, Hamid Salehiniya, Tahereh Yaghoubi Journal of Education and Health Promotion.2021; 10(1): 401. CrossRef
|