| Surulivelrajan Mallayasamy | 1 Article |
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<b>Objectives</b>
<p>Inadequate glycemic control amongst patients with Type 2 diabetes mellitus (T2DM) indicates a major public health problem and a significant risk factor for the progression and complications caused by diabetes. Glycemic control is the main therapeutic objective for the prevention of organ damage and other complications arising from diabetes.</p></sec>
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<b>Methods</b>
<p>This was a retrospective observational study of T2DM patients with complications, who were aged 40 years and older. The study was conducted retrospectively on medical records (in-patient and out-patient) obtained from a South Indian teaching hospital, Manipal, India. The patients included in the study had fasting blood sugar, postprandial blood sugar and HbA1c measured at least twice during follow-ups the previous year. Patients’ HbA1c levels were categorized into good control ≤7% (≤53mmol/mol), and poor control >7% (>53mmol/mol), and patients’ characteristics were analyzed.</p></sec>
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<b>Results</b>
<p>A total of 657 patients were included in the study. The mean age was 59.67 (SD = 9.617) years, with 152 (23.1%) females and 505 (76.9%) males, and 514 (78.2%) patients had poor glycemic control. Most of the patients were on insulin mono-therapy [<italic>n</italic> = 271 (42.1%)], about a third of the patients were on combination therapy that included an oral hypoglycemic agent and insulin [<italic>n</italic> = 236 (36.6%)]. Patients with a history of more than 10 years of diabetes [<italic>n</italic> = 293 (44.6%)], had a family history of diabetes [<italic>n</italic> = 256 (39%)] and obesity [<italic>n</italic> = 95 (14.5%)], all had poor glycemic control.</p></sec>
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<b>Conclusion</b>
<p>This present study indicated a significant association of gender (female), age, high-density lipoprotein level, duration of diabetes and type of medication, with poor glycemic control in T2DM patients that had secondary medical complications.</p></sec>
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