- Original Article
- The Characteristics of Middle Eastern Respiratory Syndrome Coronavirus Transmission Dynamics in South Korea
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Yunhwan Kim, Sunmi Lee, Chaeshin Chu, Seoyun Choe, Saeme Hong, Youngseo Shin
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Osong Public Health Res Perspect. 2016;7(1):49-55. Published online February 28, 2016
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Objectives The outbreak of Middle Eastern respiratory syndrome coronavirus (MERS-CoV) was one of the major events in South Korea in 2015. In particular, this study pays attention to formulating a mathematical model for MERS transmission dynamics and estimating transmission rates. MethodsIncidence data of MERS-CoV from the government authority was analyzed for the first aim and a mathematical model was built and analyzed... |
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- Assessment of Intensive Vaccination and Antiviral Treatment in 2009 Influenza Pandemic in Korea
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Chaeshin Chu, Sunmi Lee
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Osong Public Health Res Perspect. 2015;6(1):47-51. Published online February 28, 2015
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Objectives We characterized and assessed public health measures, including intensive vaccination and antiviral treatment, implemented during the 2009 influenza pandemic in the Republic of Korea. MethodsA mathematical model for the 2009 influenza pandemic is formulated. The transmission rate, the vaccination rate, the antiviral treatment rate, and the hospitalized rate are estimated using the least-squares method for the 2009 data of the incidence... |
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- Assessment of the Intensive Countermeasures in the 2009 Pandemic Influenza in Korea
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Jin Hyuk Choi, Yunhwan Kim, Seoyun Choe, Sunmi Lee
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Osong Public Health Res Perspect. 2014;5(2):101-107. Published online April 30, 2014
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Objectives It is critical to implement effective multiple countermeasures to mitigate or retain the spread of pandemic influenza. We propose a mathematical pandemic influenza model to assess the effectiveness of multiple countermeasures implemented in 2009. MethodsAge-specific parameters, including the transmission rate, the proportion of asymptomatic individuals, the vaccination rate, the social distancing rate, and the antiviral treatment rate are estimated using the... |
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- What Does a Mathematical Model Tell About the Impact of Reinfection in Korean Tuberculosis Infection?
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Sara Kim, Seoyun Choe, Junseong Kim, Sanga Nam, Yeon Shin, Sunmi Lee
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Osong Public Health Res Perspect. 2014;5(1):40-45. Published online February 28, 2014
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Objectives According to the Korea Centers for Disease Control and Prevention, new active tuberculosis (TB) cases have increased since 2001. Some key factors explain and characterize the transmission dynamics of Korean TB infection, such as a higher ratio of latent individuals and a new reporting system implemented in 2001, among others. MethodsWe propose a mathematical TB model that includes exogenous reinfection to... |
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- Role of Active and Inactive Cytotoxic Immune Response in Human Immunodeficiency Virus Dynamics
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Hernan Dario Toro Zapata, Angelica Graciela Caicedo Casso, Derdei Bichara, Sunmi Lee
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Osong Public Health Res Perspect. 2014;5(1):3-8. Published online February 28, 2014
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Objectives Mathematical models can be helpful to understand the complex dynamics of human immunodeficiency virus infection within a host. Most of work has studied the interactions of host responses and virus in the presence of active cytotoxic immune cells, which decay to zero when there is no virus. However, recent research highlights that cytotoxic immune cells can be inactive but never... |
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