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Seung-Hak Cho 9 Articles
Corrigendum to “Epidemiological Characterization of Imported Systemic Mycoses Occurred in Korea” [Osong Public Health Res Perspect 2018;9(5):255–60]
Seung-Hak Cho, Young-Bin Yu, Je-Seop Park, Keun-Dol Yook, Young-Kwon Kim
Osong Public Health Res Perspect. 2018;9(6):362-362.   Published online December 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.6.11
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Epidemiological Characterization of Imported Systemic Mycoses Occurred in Korea
Seung-Hak Cho, Young-Bin Yu, Je-Seop Park, Keun-Dol Yook, Young-Kwon Kim
Osong Public Health Res Perspect. 2018;9(5):255-260.   Published online October 31, 2018
DOI: https://doi.org/10.24171/j.phrp.2018.9.5.07
  • 9,156 View
  • 116 Download
  • 3 Citations
AbstractAbstract PDF
Objectives

Imported systemic mycoses is a severe fungal infection that can cause diseases in healthy people. However, there is a serious lack of epidemiological data about imported systemic mycoses. Therefore, an epidemiological characterization of imported systemic mycoses in Korea was performed.

Methods

We collected health insurance data between 2008 and 2012 from the Health Insurance Corporation and analyzed the data to determine the prevalence and treatment management of imported systemic mycoses.

Results

The prevalence of imported systemic mycoses between 2008 and 2012 increased slowly by 0.49/100,000 to 0.53/100,000 persons. The prevalence of coccidioidomycosis increased from 0.28/100,000 in 2008 to 0.36/100,000 persons in 2012. A mean of 229.6 cases occurred each year. Children and the elderly showed higher prevalence than adults in the 20- to 59-year-old age group. The rate of infection according to region ranged from 0.18/100,000 persons in Ulsan, to 0.59/100,000 persons in Gyeonggi. The prevalence in females was higher than that in males. Inpatient treatment was 3.3% (38 cases), with 96.7% treated as outpatients. Hospitalizations cost 272.7 million won and outpatient treatments cost 111.7 million won. The treatment cost for coccidioidomycosis from 2008 to 2012 was 330.9 million won, with personal charges of 79.2 million won and insurance charges of 251.7 million won. Most of the expenses for the coccidioidomycosis treatment were for inpatient treatment.

Conclusion

The results in this study may be a useful resource for determining the changes in the trend of imported systemic mycoses.

Citations

Citations to this article as recorded by  
  • The clinical laboratory evolution in coccidioidomycosis detection: Future perspectives
    José María Gastélum-Cano, Mitzuko Dautt-Castro, Alfonso García-Galaz, Katya Felix-Murray, Antonio Rascón-Careaga, Manuel A. Cano-Rangel, María A. Islas-Osuna
    Journal of Medical Mycology.2021; 31(3): 101159.     CrossRef
  • Emerging Invasive Fungal Infections: Clinical Features and Controversies in Diagnosis and Treatment Processes


    Hongliang Zhang, Aiqun Zhu
    Infection and Drug Resistance.2020; Volume 13: 607.     CrossRef
  • Timely Diagnosis of Histoplasmosis in Non-endemic Countries: A Laboratory Challenge
    María José Buitrago, M. Teresa Martín-Gómez
    Frontiers in Microbiology.2020;[Epub]     CrossRef
Characterization of Clostridium difficile Strains Isolated from Patients with C. difficile-associated Disease in Korea
Seung-Hak Cho, Jung-Whan Chon, Kun-Ho Seo, Young Kwon Kim, Jung-Beom Kim, Young-Seok Bak, Woon-Won Jung, Cheorl-Ho Kim, Jong Tae Choi
Osong Public Health Res Perspect. 2017;8(5):325-331.   Published online October 31, 2017
DOI: https://doi.org/10.24171/j.phrp.2017.8.5.06
  • 2,651 View
  • 25 Download
  • 1 Citations
AbstractAbstract PDF
Objectives

Studies on Clostridium difficile are rare in Korea. We investigated the epidemiological characteristics of C. difficile isolates from patients with C. difficile-associated disease (CDAD) in Korea.

Methods

Multiplex polymerase chain reaction was performed to detect the presence of tcdA and tcdB toxin genes. Antimicrobial susceptibility test was carried out by the disk-dilution method. C. difficile strains were subtyped by automated repetitive-element palindromic PCR (rep-PCR).

Results

Among patients with CDAD, 73 (25.8%), 32 (11.3%), 32 (11.3%), and 26 (9.2%) suffered from pneumonia, cancer or neoplasm, diabetes, and colitis, respectively. Of all stool samples, 43 samples (15.2%) were positive for C. difficile strains. We observed two expression patterns of toxin genes: tcdA+/tcdB+ (86% isolates) and tcdA−/tcdB+ (14% isolates), with all isolates expressing tcdB. Furthermore, some isolates were resistant to clindamycin (65%), ampicillin (56%), and cefazolin (40%), but all were susceptible to vancomycin and metronidazole. The tested samples were classified into diverse clusters using automated rep-PCR.

Conclusion

Our findings revealed the characteristics and antibiotic resistance of C. difficile isolates from patients in Korea. The epidemiological data may provide valuable insight into development of treatment strategies for C. difficile infections in Korea.

Citations

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  • Metronidazole therapy as initial treatment of Clostridium difficile infection in patients with chronic kidney disease in Korea
    Jaeuk Shin, Yu Mi Wi, Yu-Ji Lee
    Epidemiology and Infection.2019;[Epub]     CrossRef
Epidemiological Characterization of Skin Fungal Infections Between the Years 2006 and 2010 in Korea
Sang-Ha Kim, Seung-Hak Cho, Seung-Ki Youn, Je-Seop Park, Jong Tae Choi, Young-Seok Bak, Young-Bin Yu, Young Kwon Kim
Osong Public Health Res Perspect. 2015;6(6):341-345.   Published online December 31, 2015
DOI: https://doi.org/10.1016/j.phrp.2015.10.012
  • 2,739 View
  • 23 Download
  • 9 Citations
AbstractAbstract PDF
Objectives
The purpose of this study was to build and provide a basic database of skin fungal infections for the effective management of skin fungal infections in the future.
Methods
We collected health insurance data between the years 2006 and 2010 from the Health Insurance Corporation (Seoul, Korea) and analyzed the data to determine the prevalence and treatment management of skin fungal infections.
Results
Skin fungal infections were divided into two groups: namely dermatophytosis and other superficial mycoses. Dermatophytosis showed a higher prevalence (16,035,399 cases) than the other superficial mycoses (794,847 cases) within the study period. The prevalence rate decreased consecutively by 0.01% to 0.19% every year. The prevalence according to region showed that Jeolla-do had a high prevalence distribution. The prevalences in men and women were similar (7.01% vs. 6.26%). It is interesting to note that adults from the 50–79-year age group showed a higher prevalence than children and young adults. The average convalescence time (days) of dermatophytosis was longer than that of other superficial mycoses. The total medical expenses were also much higher in dermatophytosis than in the other superficial mycoses.
Conclusion
This study provides useful data for study trends of skin fungal infections.

Citations

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  • Prevalence and antifungal drug resistance of dermatophytes in the clinical samples from Pakistan
    Bakhtawar Usman, Abdul Rehman, Iffat Naz, Muhammad Anees
    Acta Microbiologica et Immunologica Hungarica.2021;[Epub]     CrossRef
  • Discovery of a novel and selective fungicide that targets fungal cell wall to treat dermatomycoses: 1,3‐bis(3,4‐dichlorophenoxy)propan‐2‐aminium chloride
    Daiane Flores Dalla Lana, Stefânia Neiva Lavorato, Laura Minussi Giuliani, Letícia Cruz, William Lopes, Marilene Henning Vainstein, Igor Camargo Fontana, Aline Rigon Zimmer, Murillo Araújo Freitas, Saulo Fernandes Andrade, Ricardo José Alves, Alexandre Me
    Mycoses.2020; 63(2): 197.     CrossRef
  • Voriconazole-natural latex dressings for treating infected Candida spp. skin ulcers
    Thainá V da Silva, Natan R de Barros, Caroline B Costa-Orlandi, Jean L Tanaka, Lincoln G Moro, Giovana S Pegorin, Kassandra SM Oliveira, Maria JS Mendes-Gianinni, Ana M Fusco-Almeida, Rondinelli D Herculano
    Future Microbiology.2020; 15(15): 1439.     CrossRef
  • The Pathogenesis of Fungal-Related Diseases and Allergies in the African Population: The State of the Evidence and Knowledge Gaps
    Lorraine Tsitsi Pfavayi, Elopy Nimele Sibanda, Francisca Mutapi
    International Archives of Allergy and Immunology.2020; 181(4): 257.     CrossRef
  • Medicinal Importance of Azo and Hippuric Acid Derivatives
    Tehreem Tahir, Muhammad Ashfaq, Humna Asghar, Mirza I. Shahzad, Rukhsana Tabassum, Areeba Ashfaq
    Mini-Reviews in Medicinal Chemistry.2019; 19(9): 708.     CrossRef
  • Evaluation of antifungal activity of blended cinnamon oil and usnic acid nanoemulsion using candidiasis and dermatophytosis models
    Peeyush kumar, P.W. Ramteke, Avinash C. Pandey, Himanshu Pandey
    Biocatalysis and Agricultural Biotechnology.2019; 18: 101062.     CrossRef
  • A novel approach for skin infections: Controlled release topical mats of poly(lactic acid)/poly(ethylene succinate) blends containing Voriconazole
    Neslihan Üstündağ Okur, Maria Filippousi, Mehmet Evren Okur, Şule Ayla, Emre Şefik Çağlar, Ayşegül Yoltaş, Panoraia I. Siafaka
    Journal of Drug Delivery Science and Technology.2018; 46: 74.     CrossRef
  • Serious fungal infections in Korea
    K. Huh, Y. E. Ha, D. W. Denning, K. R. Peck
    European Journal of Clinical Microbiology & Infect.2017; 36(6): 957.     CrossRef
  • Epidemiology of Fungal Infections in Patients Admitted via Emergency Department in Korea (2011~2013)
    서영우, 장태창, 박준수
    Korean Journal of Medical Mycology.2016; 21(4): 111.     CrossRef
Possibility of CTX-M-14 Gene Transfer from Shigella sonnei to a Commensal Escherichia coli Strain of the Gastroenteritis Microbiome
Seung-Hak Cho, Soon Young Han, Yeon-Ho Kang
Osong Public Health Res Perspect. 2014;5(3):156-160.   Published online June 30, 2014
DOI: https://doi.org/10.1016/j.phrp.2014.04.007
  • 1,897 View
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  • 2 Citations
AbstractAbstract PDF
Objectives
To investigated whether the CTX-M-14 gene could be transferred from a clinical Shigella sonnei strain to commensal Escherichia coli strain in the gastroenteritis microbiome.
Methods
E. coli strains were isolated from 30 stool samples of S. sonnei infected students in a gastroenteritis outbreak in 2004 and were characterized by antibiotic resistance analysis, in vitro conjugation and in vivo transfer of CTX-M-14 gene and molecular assays.
Results
One strain of Escherichia coli that had high levels of resistance to cefotaxime was isolated from a patient infected with S. sonnei. Isoelectric focusing showed that the E. coli and S. sonnei strains produced a β-lactamase with an isoelectric point of 8.1. Moreover, polymerase chain reaction analysis indicated that both strains possessed the same DNA sequences for CTX-M-14. The results of in vitro and in vivo conjugation showed that the efficiency of CTX-M-14 transfer from S. sonnei to E. coli was similar to CTX-M-14 transfer between E. coli strains.
Conclusion
The data suggest that the acquisition of the extended-spectrum β-lactamases gene by pathogenic bacteria in the human intestinal tract to commensal microbiome bacteria can cause serious infectious diseases.

Citations

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  • Healthy broilers disseminate antibiotic resistance in response to tetracycline input in feed concentrates
    S. Sreejith, Shamna Shajahan, P.R. Prathiush, V.M. Anjana, Arathy Viswanathan, Vishnu Chandran, G.S. Ajith Kumar, R. Jayachandran, Jyothis Mathew, E.K. Radhakrishnan
    Microbial Pathogenesis.2020; 149: 104562.     CrossRef
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    Masoumeh Navidinia, Mehdi Goudarzi, Samira Molaei Rameshe, Zahra Farajollahi, Pedram Ebadi Asl, Saeed Zaka khosravi, Mohammad Reza Mounesi
    Journal of Pure and Applied Microbiology.2017; 11(2): 779.     CrossRef
Prevalence of Antimicrobial Resistance in Escherichia coli Strains Isolated from Fishery Workers
Hyun-Ho Shin, Seung-Hak Cho
Osong Public Health Res Perspect. 2013;4(2):72-75.   Published online April 30, 2013
DOI: https://doi.org/10.1016/j.phrp.2013.03.001
  • 2,036 View
  • 15 Download
  • 6 Citations
AbstractAbstract PDF
Objectives
This study aimed to characterize the prevalence of antibiotic resistance in Escherichia coli isolates from the fecal samples of fishery workers who work in fish farms and often use antibiotics for the feeding fishes.
Methods
Seventy-three E. coli strains isolated from the fecal samples of fishery workers and 180 isolates from a control group of restaurant workers were tested for antibiotic resistance by agar disk diffusion with 16 antimicrobial agents.
Results
About 30% of isolates from each group showed antimicrobial resistance to ampicillin, and 60% of isolates from fishery workers and 41% from restaurant workers were resistant to tetracycline. The isolates showed higher resistance to cephalothin and cefoxitin than to other cephem antibiotics and to gentamicin than to other aminogycosides. Our data indicated that fecal E. coli isolates from fishery workers showed higher antibiotic resistance than those of non-fishery workers (restaurant workers), especially to cephalothin, tetracycline, and trimethoprim–sulfamethoxazole (p < 0.05). However, rates of multidrug resistance were similar among the fishery workers and restaurant workers.
Conclusion
Frequent use of antibiotics may cause increased antibiotic resistance in the human microbiome.

Citations

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  • Enhanced catalytic performance of Cu2ZnSnS4/MoS2 nanocomposites based counter electrode for Pt-free dye-sensitized solar cells
    P. Baskaran, K.D. Nisha, S. Harish, H. Ikeda, J. Archana, M. Navaneethan
    Journal of Alloys and Compounds.2022; 894: 162166.     CrossRef
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    Optik.2021; 242: 166998.     CrossRef
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    Kelly Thornber, David Verner‐Jeffreys, Steve Hinchliffe, Muhammad Meezanur Rahman, David Bass, Charles R. Tyler
    Reviews in Aquaculture.2020; 12(2): 966.     CrossRef
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    Anna Ławniczek-Wałczyk, Rafał L. Górny
    Occupational Safety – Science and Practice.2019; 579(12): 9.     CrossRef
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    Emily K. Rousham, Leanne Unicomb, Mohammad Aminul Islam
    Proceedings of the Royal Society B: Biological Sci.2018; 285(1876): 20180332.     CrossRef
  • Possibility of CTX-M-14 Gene Transfer from Shigella sonnei to a Commensal Escherichia coli Strain of the Gastroenteritis Microbiome
    Seung-Hak Cho, Soon Young Han, Yeon-Ho Kang
    Osong Public Health and Research Perspectives.2014; 5(3): 156.     CrossRef
Comparison of Antimicrobial Resistance in Escherichia coli Strains Isolated From Healthy Poultry and Swine Farm Workers Using Antibiotics in Korea
Seung-Hak Cho, Yeong-Sik Lim, Yeon-Ho Kang
Osong Public Health Res Perspect. 2012;3(3):151-155.   Published online June 30, 2012
DOI: https://doi.org/10.1016/j.phrp.2012.07.002
  • 1,897 View
  • 20 Download
  • 20 Citations
AbstractAbstract PDF
Objectives
The aim of this study is to compare the antibiotic resistance of Escherichia coli isolates from faecal samples of workers who often use antibiotics.
Methods
A total of 163E coli strains isolated from faecal samples of livestock workers (poultry and swine farm workers) and restaurant workers in the same regions as a control group were analyzed by agar disc diffusion to determine their susceptibility patterns to 16 antimicrobial agents.
Results
Most of the tested isolates showed high antimicrobial resistance to ampicillin and tetracycline. The isolates showed higher resistance to cephalothin than other antibiotics among the cephems. Among the aminoglycosides, the resistance to gentamicin and tobramycin occurred at higher frequencies compared with resistance to amikacin and netilmicin. Our data indicated that faecal E coli isolates of livestock workers showed higher antibiotic resistances than nonlivestock workers (restaurant workers), especially cephalothin, gentamicin, and tobramycin (p < 0.05). Moreover, the rates of the livestock workers in the association of multidrug resistance were also higher than the rates of the restaurant workers.
Conclusion
This study implies that usage of antibiotics may contribute to the prevalence of antibiotic resistance in commensal E coli strains of humans.

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    Poultry.2022; 1(2): 94.     CrossRef
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    Microbial Biotechnology.2021; 14(3): 886.     CrossRef
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    Antibiotics.2021; 10(1): 68.     CrossRef
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    Oswaldo Santos Baquero
    Frontiers in Public Health.2021;[Epub]     CrossRef
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    Gene Reports.2020; 21: 100926.     CrossRef
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    Mabel Kamweli Aworh, Jacob Kwaga, Emmanuel Okolocha, Nwando Mba, Siddhartha Thakur, Grzegorz Woźniakowski
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    Scientific Reports.2018;[Epub]     CrossRef
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    Shengnan Zhao, Chia-Lan Wang, Shao-Kuang Chang, Yi-Lun Tsai, Chung-Hsi Chou
    Avian Diseases.2018; 63(1): 9.     CrossRef
  • Changes in antimicrobial resistance patterns and dominance of extended spectrum β-lactamase genes among faecal Escherichia coli isolates from broilers and workers during two rearing periods
    Fatemeh Doregiraee, Masoud Alebouyeh, Bahar Nayeri Fasaei, Saeed Charkhkar, Elahe Tajeddin, Mohammad Reza Zali
    Italian Journal of Animal Science.2018; 17(3): 815.     CrossRef
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    Katarzyna Ignasiak, Anthony Maxwell
    BMC Microbiology.2018;[Epub]     CrossRef
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    Tae-Ok Kim, In-Seon Eom, Kwang-Ho Park, Kwon-Sam Park
    Korean Journal of Fisheries and Aquatic Sciences.2016; 49(6): 800.     CrossRef
  • High prevalence of cross-resistance to fluoroquinolone and cotrimoxazole in tetracycline-resistant Escherichia coli human clinical isolates
    Eric Batard, Mathilde Lefebvre, Guillaume Ghislain Aubin, Nathalie Caroff, Stéphane Corvec
    Journal of Chemotherapy.2016; 28(6): 510.     CrossRef
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    Jinxin Liu, Zhe Zhao, Lisa Orfe, Murugan Subbiah, Douglas R. Call
    Environmental Microbiology.2016; 18(2): 557.     CrossRef
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    Helen M. Sancheza, Cristina Echeverria, Vanessa Thulsiraj, Amy Zimmer-Faust, Ariel Flores, Madeleine Laitz, Gregory Healy, Shaily Mahendra, Suzanne E. Paulson, Yifang Zhu, Jennifer A. Jay
    Water, Air, & Soil Pollution.2016;[Epub]     CrossRef
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    Chaoqi Chen, Jing Li, Stephanie L. DeVries, Pengfei Zhang, Xiqing Li
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  • Possibility of CTX-M-14 Gene Transfer from Shigella sonnei to a Commensal Escherichia coli Strain of the Gastroenteritis Microbiome
    Seung-Hak Cho, Soon Young Han, Yeon-Ho Kang
    Osong Public Health and Research Perspectives.2014; 5(3): 156.     CrossRef
  • A survey of the frequency of aminoglycoside antibiotic-resistant genotypes and phenotypes inEscherichia coliin broilers with septicaemia in Hebei, China
    F.Y. Zhang, S.Y. Huo, Y.R. Li, R. Xie, X.J. Wu, L.G. Chen, Y.H. Gao
    British Poultry Science.2014; 55(3): 305.     CrossRef
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    Hyun-Ho Shin, Seung-Hak Cho
    Osong Public Health and Research Perspectives.2013; 4(2): 72.     CrossRef
Prevalence of Antibiotic Resistance in Escherichia coli Fecal Isolates From Healthy Persons and Patients With Diarrhea
Seung-Hak Cho, Yeong-Sik Lim, Mi-Sun Park, Seong-Han Kim, Yeon-Ho Kang
Osong Public Health Res Perspect. 2011;2(1):41-45.   Published online June 30, 2011
DOI: https://doi.org/10.1016/j.phrp.2011.05.003
  • 1,904 View
  • 16 Download
  • 10 Citations
AbstractAbstract PDF
Objectives
This study aimed to investigate the prevalence of antibiotic resistance in fecal Escherichia coli isolates from healthy persons and patients with diarrhea.
Methods
E. coli isolates (n = 428) were obtained from fecal samples of apparently healthy volunteers and hospitalized patients with diarrhea. Susceptibility patterns of isolates to 16 antimicrobial agents were determined by agar disc diffusion.
Results
Most E. coli isolates exhibited less than 10% resistance against imipenem, cefotetan, aztreonam, cefepime, cefoxitin, amikacin and netilamicin, although greater than 65% were resistant to ampicillin and tetracycline. No significant difference in resistance rates for all tested antibiotics was found between isolates from the healthy-and diarrheal-patient groups, including for multi-drug resistance (p = 0.22). The highest number of resistant antibiotics was 12 antibiotics. No significant differences in antibiotic resistance were found among the sex and age strata for isolates from healthy individuals. However, antibiotic resistance rates to cefoxitin, cefotaxime, amikacin, and netilamicin were significantly higher in the isolates of men than those of women (p < 0.05) in isolates from patients with diarrhea. Furthermore, isolates from patients with diarrhea older than 40-years of age showed higher resistance to cefepime and aztreonam (p < 0.05).
Conclusion
High resistance to the antibiotics most frequently prescribed for diarrhea was found in isolates from patients with diarrhea and apparently healthy individuals without any significant difference.

Citations

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    Salma Bessalah, John Morris Fairbrother, Imed Salhi, Ghyslaine Vanier, Touhami Khorchani, Mabrouk-Mouldi Seddik, Mohamed Hammadi
    Animal Biotechnology.2021; 32(6): 748.     CrossRef
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    Son Thi Thanh Dang, Duong Thi Quy Truong, John Elmerdahl Olsen, Nhat Thi Tran, Giang Thi Huong Truong, Hue Thi Kim Vu, Anders Dalsgaard
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    Raquel Mota, Marisa Pinto, Josman Palmeira, Daniela Gonçalves, Helena Ferreira
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  • Possibility of CTX-M-14 Gene Transfer from Shigella sonnei to a Commensal Escherichia coli Strain of the Gastroenteritis Microbiome
    Seung-Hak Cho, Soon Young Han, Yeon-Ho Kang
    Osong Public Health and Research Perspectives.2014; 5(3): 156.     CrossRef
  • Prevalence of Antimicrobial Resistance in Escherichia coli Strains Isolated from Fishery Workers
    Hyun-Ho Shin, Seung-Hak Cho
    Osong Public Health and Research Perspectives.2013; 4(2): 72.     CrossRef
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    Chaeshin Chu
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Distribution of Virulence Genes and Their Association of Serotypes in Pathogenic Escherichia coli Isolates From Diarrheal Patients in Korea
Seung-Hak Cho, Kyung-Hwan Oh, Seong-Han Kim, Hee-Bok Oh, Mi-Sun Park
Osong Public Health Res Perspect. 2010;1(1):29-35.   Published online December 31, 2010
DOI: https://doi.org/10.1016/j.phrp.2010.12.008
  • 2,112 View
  • 15 Download
  • 6 Citations
AbstractAbstract PDF
Objectives
To characterise the genetic and serological diversity of pathogenic Escherichia coli, we tested 111 E coli strains isolated from diarrhoeal patients in Korea between 2003 and 2006.
Methods
The isolates were tested through polymerase chain reaction (PCR) and slide agglutination method for the detection of virulence genes and serotypes, respectively. To compare the expression of Shiga toxin (stx)-1 and stx2 genes, real-time quantitative reverse-transcriptase PCR and rapid exprssion assay, reversed-passive latex agglutination, were performed.
Results
Forty-nine Shiga toxin-producing E coli (STEC) strains and 62 non-STEC strains, including 20 enteropathogenic E coli, 20 enterotoxigenic E coli, 20 enteroaggregative E coli, and 2 enteroinvasive E coli were randomly chosen from the strains isolated from diarrhoeal patients in Korea between 2003 and 2006. PCR analysis indicated that locus of enterocyte effacement pathogenicity island, that is, eaeA, espADB, and tir genes were present in STEC, enteropathogenic E coli, and enteroinvasive E coli. Quorum sensing-related gene luxS was detected in most of pathogenic E coli strains. Major serotypes of the STEC strains were O157 (26%) and O26 (20%), whereas the non-STEC strains possessed various serotypes. Especially, all the strains with serotype O157 carried stx2 and the tested virulence factors. Of the STEC strains, the data of real-time quantitative reverse-transcriptase PCR and reversed-passive latex agglutination tests showed that messenger RNA- and protein expression of stx2 gene were higher than those of stx1 gene.
Conclusion
Our results provide the epidemiological information regarding the trend of STEC and non-STEC infections in the general population and show the fundamental data in association of serotypes with virulence genes in diarrhoeagenic E coli strains from Korea.

Citations

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