- Enrolment Phase Results of the Tabari Cohort Study: Comparing Family History, Lipids and Anthropometric Profiles Among Diabetic Patients
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Mahmood Moosazadeh, Mahdi Afshari, Kaveh Jafari, Motahareh Kheradmand, Zahra Kashi, Mohsen Aarabi, Adeleh Bahar, Mohammad Khademloo
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Osong Public Health Res Perspect. 2019;10(5):289-294. Published online October 31, 2019
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DOI: https://doi.org/10.24171/j.phrp.2019.10.5.05
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Abstract
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Objectives
Different factors are responsible for the silent epidemic of diabetes mellitus in developing and developed countries. This study aimed to determine the role of demographic factors, lipid profile, family history (the estimation of genetic association) and anthropometric factors on diabetes onset.
Methods
Data from the enrolment phase of the Tabari Cohort study was applied for this study and included 10,255 participants aged between 35–70 years. Anthropometric variables were measured by trained staff using standard tools. Blood specimens were collected for lipid profile and blood glucose measurements. Data analyses were performed using SPSS version 24, with univariate and multivariate logistic regression.
Results
The prevalence of diabetes mellitus was estimated to be 17.2% in the cohort population, 15.6% in men, and 18.3% in women. The adjusted odds ratios (95% confidence intervals) for age groups 40–49, 50–59 and over 60 were 2.58 (2.20–3.69), 5.80 (4.51–7.48) and 8.72 (6.67–11.39), respectively. In addition, the odds ratios (95% confidence intervals) for 2 (or more), and 1 affected family member were 4.12 (3.55–4.90) and 2.34 (2.07–2.65), respectively. Triglyceride concentrations more than 500, and abnormal high-density lipoprotein levels increased the odds of diabetes mellitus by 3.29- and 1.18-fold, respectively.
Conclusion
The current study showed that old age and a family history were strong predictors for diabetes mellitus.
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Citations
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- The prevalence and determinants of diabetes mellitus and thyroid disorder comorbidity in Tabari cohort population
Mahmood Moosazadeh, Saeedeh Khakhki, Adele Bahar, Akbar Hedayatizadeh-Omran, Motahareh Kheradmand, Reza Alizadeh-Navaei, Erfan Ghadirzadeh Scientific Reports.2024;[Epub] CrossRef - Free-fatty acid receptor-4 gene polymorphism (rs61866610) and colorectal cancer risk
Ramin Shekarriz, Maryam Hasanian, Mohadeseh Ahmadi, Versa Omrani-Nava, Reza Alizadeh-Navaei Nucleosides, Nucleotides & Nucleic Acids.2024; : 1. CrossRef - The relationship between spiritual intelligence and self-management in patients with diabetes type 1
Sima Rafiei, Saber Souri, Zahra Nejatifar, Mohammad Amerzadeh BMC Endocrine Disorders.2023;[Epub] CrossRef - Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)
Sanam Hariri, Zahra Rahimi, Nahid Hashemi-Madani, Seyyed Ali Mard, Farnaz Hashemi, Zahra Mohammadi, Leila Danehchin, Farhad Abolnezhadian, Aliasghar Valipour, Yousef Paridar, Mohammad Mahdi Mir-Nasseri, Alireza Khajavi, Sahar Masoudi, Saba Alvand, Bahman BMC Endocrine Disorders.2021;[Epub] CrossRef
- Epidemiological and Clinical Features of People with Malta Fever in Iran: A Systematic Review and Meta-Analysis
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Mahmood Moosazadeh, Roja Nikaeen, Ghasem Abedi, Motahareh Kheradmand, Saeid Safiri
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Osong Public Health Res Perspect. 2016;7(3):157-167. Published online June 30, 2016
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DOI: https://doi.org/10.1016/j.phrp.2016.04.009
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4,300
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25
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Abstract
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- Objectives
Numerous studies have reported the epidemiological and clinical features of Malta fever incidence in Iran. Review and synthesis of the related literature through meta-analysis can provide an appropriate measurement for aforementioned indices. Therefore, the present study aimed to determine the epidemiological and clinical features of people with Malta fever in Iran. Methods
The required documents were obtained through searching national and international databases. In each study, standard deviation of the indices was calculated using binomial distribution formulas. Finally, the heterogeneity index was determined between studies using Cochran (Q) and I2 tests. Results
Combining the results of 47 articles in the meta-analysis indicated that 57.6% (55.02–60.1%) and 42.3% (49.8–44.9%) of the patients were male and female, respectively. Most of the patients lived in rural areas; 68.4% (63.6–73.2%) compared to 31.4% (26.7–36.3%). In addition, 20.8% (17.4–24.2%) of the patients were ranchers and farmers, 16.9% (14.5–19.4%) were students, and 31.6% (27–36.2%) were housewives. Of the patients studies, 50.5% (35.6–65.2%) experienced contact with animals and 57.1% (46.4–67.9%) used unpasteurized dairy products. Fever, joint pain, and sweating were detected among 65.7% (53.7–77.8%) and 55.3% (44.4–66.2%), respectively. Conclusion
The present study revealed that the frequency of male patients with brucellosis was considerably more than that of female patients. The number of patients with Malta fever in rural areas was significantly more than in urban areas. High-risk behavior, unprotected contact with animals, and using unpasteurized dairy products were among the most significant factors affecting Malta fever incidence in Iran. Fever, joint pain, and sweating were detected among most of the patients with Malta fever.
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