Skip Navigation
Skip to contents

PHRP : Osong Public Health and Research Perspectives


Author index

Page Path
HOME > Articles and issues > Author index
Min Ji Kim 1 Article
Diversity of Rotavirus Strain Circulated in Gwangju, Republic of Korea
Min Ji Kim, Hye Sook Jeong, Seon Gyeong Kim, Se Mi Lee, Sun Hee Kim, Hye-Young Kee, Eun-hye Jo, Hye-jung Park, Dong-Ryong Ha, Eun Sun Kim, Kye-Won Seo, Jae Keun Chung
Osong Public Health Res Perspect. 2014;5(6):364-369.   Published online December 31, 2014
  • 3,515 View
  • 24 Download
  • 3 Crossref
AbstractAbstract PDF
The introduction of new rotavirus vaccines into the public sphere makes it necessary to maintain constant surveillance and to heighten public awareness of the appearance of new rotavirus strains. We describe the molecular epidemiology of circulating rotavirus strains after vaccine introduction.
We collected a total of 1070 stool samples from children with gastroenteritis from January 2013 to June 2013. The antigenic prevalence of rotavirus group A was distinguished using enzyme immunoassay. The G and P genotypes of enzyme immunoassay-positive samples were determined with reverse transcription-polymerase chain reaction and nucleotide sequencing analysis.
Of the 1070 samples collected, 277 (25.9%) tested positive for rotaviruses by enzyme-linked immunoabsorbent assay. The most prevalent circulating genotype G was G1 (51.3%), followed by G2 (34.7%) and G9 (10.8%). The predominant type of genotype P was P[8] (66.1%), followed by P[4] (31.4%). In this study, nine genotypes were found. G1P[8] was the most prevalent (51.8%), followed by G2P[4] (30.5%), G9P[8] (9.9%), and G2P[8] (4.0%). Several unusual combinations (G1P[4], G3P[9], G3P[8], G4P[6], and G9P[4]) were also identified.
Molecular epidemiological knowledge of rotaviruses is critical for the development of effective preventive measures, including vaccines. These data will help us monitor the effectiveness of current rotavirus vaccines.


Citations to this article as recorded by  
  • Rotavirus infection among hospitalized children under five years of age with acute watery diarrhea in Sri Lanka
    Paba Palihawadana, Gagandeep Kang, Janakan Navaratnasingam, Geethani Galagoda, Janaki Abeynayake, Madhava Gunasekera, Shilanthi Seneviratne
    Vaccine.2018; 36(51): 7846.     CrossRef
  • Complete genome sequence analysis of rare G4P[6] rotavirus strains from human and pig reveals the evidence for interspecies transmission
    Rungnapa Malasao, Pattara Khamrin, Kattareeya Kumthip, Hiroshi Ushijima, Niwat Maneekarn
    Infection, Genetics and Evolution.2018; 65: 357.     CrossRef
  • Post-marketing safety surveillance conducted in Korea (2008–2013) following the introduction of the rotavirus vaccine, RIX4414 (Rotarix™)
    Son Moon Shin, Chun Soo Kim, Naveen Karkada, Aixue Liu, Girish Jayadeva, Htay Htay Han
    Human Vaccines & Immunotherapeutics.2016; 12(10): 2590.     CrossRef

PHRP : Osong Public Health and Research Perspectives