Skip Navigation
Skip to contents

PHRP : Osong Public Health and Research Perspectives

OPEN ACCESS
SEARCH
Search

Author index

Page Path
HOME > Articles and issues > Author index
Search
Mery Ramadani 1 Article
Prenatal Secondhand Smoke Exposure: Correlation Between Nicotine in Umbilical Cord Blood and Neonatal Anthropometry
Mery Ramadani, Budi Utomo, Endang L Achadi, Hartono Gunardi
Osong Public Health Res Perspect. 2019;10(4):234-239.   Published online August 31, 2019
DOI: https://doi.org/10.24171/j.phrp.2019.10.4.06
  • 3,715 View
  • 85 Download
  • 4 Citations
AbstractAbstract PDF
Objectives

Nicotine narrows uterine blood vessels reducing the flow of oxygen and nutrients to the developing fetus. This study examined the effects of fetal exposure to secondhand smoke on neonatal anthropometry.

Methods

This cross sectional study recruited 128 pregnant women in the third trimester of single pregnancies who had no chronic illness, were not active or ex-smokers, and who were willing to participate in the study. Pregnant women who were exposed to secondhand smoke had umbilical cord blood nicotine concentrations of ≥ 1 ng/mL. Neonatal anthropometry was assessed according to the newborn birth weight and length. The independent t-test was used to determine the neonatal difference in mean birth weight and length between the women who were exposed to secondhand smoke, and those who were not exposed. A multiple linear regression analysis was employed to assess the effect of secondhand smoke exposure on birth weight and birth length, controlling for potential confounding variables (weight gain during pregnancy, body mass index, parity, maternal age, and maternal hemoglobin).

Results

There were 35 women exposed to secondhand smoke (nicotine ≥ 1 ng/mL). Neonate birth weight and birth length were lower among mothers who were exposed to secondhand smoke. However, only neonate birth weight was significantly reduced by exposure to secondhand smoke (p = 0.005). The mean birth weight of these neonates was 2,916.5 g ± 327.3 g which was 205.6 g less than in unexposed fetuses.

Conclusion

Exposure of mothers to secondhand smoke during pregnancy reduces fetal development and neonatal weight.

Citations

Citations to this article as recorded by  
  • Sex differences and heritability of adrenal steroidogenesis in offspring rats induced by prenatal nicotine exposure
    Yawen Chen, Fangfang Duan, Lian Liu, Guanghui Chen, Zheng He, Hegui Huang, Hui Wang
    The Journal of Steroid Biochemistry and Molecular .2022; 221: 106102.     CrossRef
  • Improving the Healthy Family Index to Prevent Stunting among Children aged 0–59 Months in Indonesia
    Kadar Ramadhan, Nurfatimah Nurfatimah, Fahmi Hafid, Rudy Hartono, Zakaria Zakaria, Bohari Bohari
    Open Access Macedonian Journal of Medical Sciences.2022; 10(E): 752.     CrossRef
  • Cigarette smoke exposure and increased risks of stunting among under-five children
    Dyah Dwi Astuti, Tri Widyastuti Handayani, Duwi Pudji Astuti
    Clinical Epidemiology and Global Health.2020; 8(3): 943.     CrossRef
  • Nicotine and Its Downstream Metabolites in Maternal and Cord Sera: Biomarkers of Prenatal Smoking Exposure Associated with Offspring DNA Methylation
    Parnian Kheirkhah Rahimabad, Thilani M. Anthony, A. Daniel Jones, Shakiba Eslamimehr, Nandini Mukherjee, Susan Ewart, John W. Holloway, Hasan Arshad, Sarah Commodore, Wilfried Karmaus
    International Journal of Environmental Research an.2020; 17(24): 9552.     CrossRef

PHRP : Osong Public Health and Research Perspectives