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Kaveh Jafari 1 Article
Enrolment Phase Results of the Tabari Cohort Study: Comparing Family History, Lipids and Anthropometric Profiles Among Diabetic Patients
Mahmood Moosazadeh, Mahdi Afshari, Kaveh Jafari, Motahareh Kheradmand, Zahra Kashi, Mohsen Aarabi, Adeleh Bahar, Mohammad Khademloo
Osong Public Health Res Perspect. 2019;10(5):289-294.   Published online October 31, 2019
DOI: https://doi.org/10.24171/j.phrp.2019.10.5.05
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  • 1 Citations
AbstractAbstract PDF
Objectives

Different factors are responsible for the silent epidemic of diabetes mellitus in developing and developed countries. This study aimed to determine the role of demographic factors, lipid profile, family history (the estimation of genetic association) and anthropometric factors on diabetes onset.

Methods

Data from the enrolment phase of the Tabari Cohort study was applied for this study and included 10,255 participants aged between 35–70 years. Anthropometric variables were measured by trained staff using standard tools. Blood specimens were collected for lipid profile and blood glucose measurements. Data analyses were performed using SPSS version 24, with univariate and multivariate logistic regression.

Results

The prevalence of diabetes mellitus was estimated to be 17.2% in the cohort population, 15.6% in men, and 18.3% in women. The adjusted odds ratios (95% confidence intervals) for age groups 40–49, 50–59 and over 60 were 2.58 (2.20–3.69), 5.80 (4.51–7.48) and 8.72 (6.67–11.39), respectively. In addition, the odds ratios (95% confidence intervals) for 2 (or more), and 1 affected family member were 4.12 (3.55–4.90) and 2.34 (2.07–2.65), respectively. Triglyceride concentrations more than 500, and abnormal high-density lipoprotein levels increased the odds of diabetes mellitus by 3.29- and 1.18-fold, respectively.

Conclusion

The current study showed that old age and a family history were strong predictors for diabetes mellitus.

Citations

Citations to this article as recorded by  
  • Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)
    Sanam Hariri, Zahra Rahimi, Nahid Hashemi-Madani, Seyyed Ali Mard, Farnaz Hashemi, Zahra Mohammadi, Leila Danehchin, Farhad Abolnezhadian, Aliasghar Valipour, Yousef Paridar, Mohammad Mahdi Mir-Nasseri, Alireza Khajavi, Sahar Masoudi, Saba Alvand, Bahman
    BMC Endocrine Disorders.2021;[Epub]     CrossRef

PHRP : Osong Public Health and Research Perspectives