- Original Article
- Proteomic Analysis of Intracellular and Membrane Proteins From Voriconazole-Resistant Candida glabrata
-
Jae Il Yoo, Hwa Su Kim, Chi Won Choi, Jung Sik Yoo, Jae Yon Yu, Yeong Seon Lee
-
Osong Public Health Res Perspect. 2013;4(6):293-300. Published online December 31, 2013
-
|
|
Objectives
The proteomic analysis of voriconazole resistant Candida glabrata strain has not yet been investigated. In this study, differentially expressed proteins of intracellular and membrane fraction from voriconazole-susceptible, susceptible dose-dependent (S-DD), resistant C. glabrata strains were compared with each other and several proteins were identified.
Methods
The proteins of intracellular and membrane were isolated by disrupting cells with glass bead and centrifugation from... |
-
-
- Articles
- Proteomic Analysis of Cellular and Membrane Proteins in Fluconazole-Resistant Candida glabrata
-
Jae Il Yoo, Chi Won Choi, Hwa Su Kim, Jung Sik Yoo, Young Hee Jeong, Yeong Seon Lee
-
Osong Public Health Res Perspect. 2012;3(2):74-78. Published online June 30, 2012
-
|
|
Objectives
Candida glabrata is one of the most common causes of Candida bloodstream infections worldwide. Some isolates of C glabrata may be intermediately resistant to azoles, with some strains developing resistance during therapy or prophylaxis with fluconazole. In this study, we used a proteomic approach to identify differentially expressed proteins between fluconazoleresistant and -susceptible strains.
Methods
Membrane and cellular proteins were extracted from... |
-
-
- Original Article
- Gene Expression and Identification Related to Fluconazole Resistance of Candida glabrata Strains
-
Jae Il Yoo, Chi Won Choi, Kyeong Min Lee, Yeong Seon Lee
-
Osong Public Health Res Perspect. 2010;1(1):36-41. Published online December 31, 2010
-
|
|
Objectives
Candida glabrata has become one of the most common causes of Candida bloodstream infections worldwide. Some strains of C. glabrata may be intermediately resistant to all azoles. The several possible mechanisms of azole resistance have been reported previously, but the exact resistant mechanism is not clear. In this study, we identified differentially expressed genes (DEGs) of fluconazole-resistant C. glabrata and... |
-
-
|
