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Bo-Ra Jeon 1 Article
Impact of Mixed Cognitive Intervention Training on Early Onset Dementia
Bo-Ra Jeon, Deok-Ju Kim
Osong Public Health Res Perspect. 2021;12(1):29-36.   Published online February 23, 2021
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  • 2 Crossref
AbstractAbstract PDF

The aim of this study was to investigate the impact of mixed cognitive intervention training using spaced retrieval training, and errorless learning in participants with early onset dementia. This was based on reality orientation therapy for cognitive function, depression, and occupational performance of patients.


Two early onset vascular dementia patients (> 65 years) with mild or moderate impairment were enrolled in a pre-test - post-test single-subject research design study. Prior to the study, the caregivers were interviewed about meaningful times, people, places, and areas of interest for the participant. A list of individual training words were selected based upon this information, and the participant was instructed to recall them after a 45-second, 90-second, 6-minute, and 12-minute delay. Baseline (3 sessions), intervention (20 sessions), and a second baseline period (3 sessions) were conducted. Activities of daily living were measured, and cognition was measured using the Consortium to Establish a Registry of Alzheimer’s Disease Korean version, whilst depression was measured using the Korean Form Geriatric Depression Scale, and task performance and satisfaction measured by the Canadian Occupational Performance Measure.


After intervention, both participants showed improvements in activities of daily living (ADL), word list memory/recognition, trail making A, occupational performance, and satisfaction improvement, which was clinically significant in 1 participant who also had a reduced score in the scale of depression classifying him as not depressed.


Spaced retrieval training and errorless learning based on reality orientation therapy is an effective intervention in patients with early onset dementia and mild or moderate impairment.


Citations to this article as recorded by  
  • Non‐pharmacological interventions for people living with young‐onset dementia and their carers: A scoping review focussing on the support of participants' needs
    Iktae Kim, Yoosun Yang, Hongjin Cheon, Jiyeon Kim, Jun‐Ah Song
    Journal of Psychiatric and Mental Health Nursing.2024; 31(1): 14.     CrossRef
  • Interventions for Persons with Young-Onset Dementia and Their Families: A Scoping Review
    Xiaoyan Cui, Junqiao Wang, Bei Wu, Qianhua Zhao, Xueting Tang, Jing Wang
    Journal of Alzheimer's Disease.2024; 97(4): 1519.     CrossRef

PHRP : Osong Public Health and Research Perspectives