- The role of lipids in the pathophysiology of coronavirus infections
-
Milad Zandi, Parastoo Hosseini, Saber Soltani, Azadeh Rasooli, Mona Moghadami, Sepideh Nasimzadeh, Farzane Behnezhad
-
Osong Public Health Res Perspect. 2021;12(5):278-285. Published online October 15, 2021
-
DOI: https://doi.org/10.24171/j.phrp.2021.0153
-
-
7,740
View
-
187
Download
-
3
Web of Science
-
4
Crossref
-
 Graphical Abstract
 Abstract
 PDF
 - Coronaviruses, which have been known to cause diseases in animals since the 1930s, utilize cellular components during their replication cycle. Lipids play important roles in viral infection, as coronaviruses target cellular lipids and lipid metabolism to modify their host cells to become an optimal environment for viral replication. Therefore, lipids can be considered as potential targets for the development of antiviral agents. This review provides an overview of the roles of cellular lipids in different stages of the life cycle of coronaviruses.
-
Citations
Citations to this article as recorded by  - Homeostasis of Calnexin Is Essential for the Growth, Virulence, and Hypovirus RNA Accumulation in the Chestnut Blight Fungus
Tao Huang, Xiaoling Ma, Ziqi Zhao, Danna Qin, Weiye Qin, Jinzi Wang, Baoshan Chen, Xipu He
Molecular Microbiology.2025;[Epub] CrossRef - PEDV inhibits HNRNPA3 expression by miR-218-5p to enhance cellular lipid accumulation and promote viral replication
Xiaojie Shi, Qi Zhang, Naling Yang, Quanqiong Wang, Yanxia Zhang, Xingang Xu, Xiang-Jin Meng, Ying Fang
mBio.2024;[Epub] CrossRef - Understanding the Molecular Actions of Spike Glycoprotein in SARS-CoV-2 and Issues of a Novel Therapeutic Strategy for the COVID-19 Vaccine
Yasunari Matsuzaka, Ryu Yashiro
BioMedInformatics.2024; 4(2): 1531. CrossRef - Orsay Virus Infection of Caenorhabditis elegans Is Modulated by Zinc and Dependent on Lipids
Luis Alberto Casorla-Perez, Ranya Guennoun, Ciro Cubillas, Bo Peng, Kerry Kornfeld, David Wang, Rebecca Ellis Dutch
Journal of Virology.2022;[Epub] CrossRef
|
