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- Aflatoxin M1 Contamination Levels in Cheeses Sold in Isfahan Province, Iran
- Ali Sharifzadeh, Payam Ghasemi-Dehkordi, Mohsen Foroughi, Elham Mardanpour-Shahrekordi, Shahin Ramazi
- Osong Public Health Res Perspect. 2017;8(4):260-263. Published online August 31, 2017
- DOI: https://doi.org/10.24171/j.phrp.2017.8.4.05
- 4,057 View
- 25 Download
- 15 Crossref
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Abstract
PDF Objectives Aflatoxin M1 (AFM1)-contaminated dairy products pose serious human health risks, causing liver and renal failure if consumed. They are also related to decreased milk and egg production in infected animals. This study investigated the AFM1 contamination levels in cheeses sold in Isfahan province, Iran, by enzyme-linked immunosorbent assay (ELISA).
Methods A total of 100 white cheese samples were randomly collected from supermarkets in Isfahan province and after extraction using dichloromethane were prepared for the ELISA.
Results Of the 100 samples, 52 (52%) were contaminated by AFM1, at levels ranging from 50.2 to 424.4 ng/kg. The remaining 48% of the samples had undetectable AFM1 levels (< 50 ng/kg). Based on the standard limit set by the European Commission and Iran, 8% (8/100) of the AFM1-positive samples (with concentrations between 250.2 and 424.4 ng/kg) had levels higher than the permissible value of 250 ng/kg.
Conclusion Although the percentage of cheese samples in Isfahan province with AFM1 levels exceeding the national permissible limit was low, the examination of cheeses and the milk used for their production is nevertheless important for ensuring public health. Furthermore, optimum storage conditions of animal feed should be ensured, and livestock nutrition must be monitored for the presence of AFM1 and other aflatoxins.
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Citations
Citations to this article as recorded by
- Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review
Tooraj Massahi, Abdullah Khalid Omer, Mohammad Hossein Habibollahi, Borhan Mansouri, Gholamreza Ebrahimzadeh, Kimya Parnoon, Hamed Soleimani, Kiomars Sharafi
Journal of Food Composition and Analysis.2024; 129: 106124. CrossRef - Current Status of Major Mycotoxins Contamination in Food and Feed in Asia─A Review
Lu Sun, Runyan Li, Bowen Tai, Sarfaraz Hussain, Gang Wang, Xiumin Liu, Fuguo Xing
ACS Food Science & Technology.2023; 3(2): 231. CrossRef - A national systematic literature review for aflatoxin M1 in commonly consumed cheese brands in Iran: Human health risk assessment by Monte Carlo simulation
Tooraj Massahi, Amir Kiani, Kiomars Sharafi, Abdullah Khalid Omer, Gholamreza Ebrahimzadeh, Jalil Jaafari, Nazir Fattahi, Kimya Parnoon
Heliyon.2023; 9(9): e19679. CrossRef - Prevalence and concentration of aflatoxin M1 and ochratoxin A in cheese: a global systematic review and meta-analysis and probabilistic risk assessment
Trias Mahmudiono, Yeganeh Mazaheri, Parisa Sadighara, Zeynab Akbarlou, Somayeh Hoseinvandtabar, Yadolah Fakhri
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Toxin Reviews.2022; 41(2): 588. CrossRef - The prevalence of aflatoxin M1 (AFM1) in conventional and industrial dairy products (yogurt, cheese, kashk and dough) of Iran: a systematic review and meta-analysis
Pouran Makhdoumi, Hooshyar Hossini, Reza Mohammadi, Mojtaba Limoee
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- Human health risk assessment of aflatoxin M1 in various dairy products in Iran: A literature review
- Exposure of Infants to Aflatoxin M1 from Mother's Breast Milk in Ilam, Western Iran
- Farajollah Maleki, Soghra Abdi, Elaham Davodian, Karimeh Haghani, Salar Bakhtiyari
- Osong Public Health Res Perspect. 2015;6(5):283-287. Published online October 31, 2015
- DOI: https://doi.org/10.1016/j.phrp.2015.10.001
- 3,104 View
- 19 Download
- 33 Crossref
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Abstract
PDF
- Objectives
Aflatoxins as a highly toxic group of mycotoxins are present in the environment and foodstuff. These have been reported to cause serious health problems in humans. Since aflatoxin M1 (AFM1) is excreted into breast milk, investigating the exposure of infants to AFM1 is of special concern.
Methods
In the present study, breast milk samples were collected from 85 lactating mothers in Ilam province, Iran, and the levels of AFM1 were analyzed using the enzyme-linked immunosorbent assay-based technique. AFM1 was detected in breast milk of all lactating women. The mean contamination level was 5.91 ± 2.031 ng/L, ranging from 2 ng/L to 10 ng/L.
Results
Multiple regression analysis indicated no significant associations of consumption of milk and dairy products, meat, fish, legumes, grain products, fruits, and nuts with the concentration of AFM1 in breast milk. Furthermore, no significant association was observed between AFM1 concentration and anthropometric data of infants.
Conclusion
In western parts of Iran, lactating mothers and their infants could be at risk of aflatoxin B1 and AFM1 exposure, respectively. Therefore, in Iran, the evaluation of AFM1 in human breast milk as a biomarker for postnatal exposure of infants to this carcinogen requires more attention in different regions and various seasons. -
Citations
Citations to this article as recorded by- Determination of aflatoxin M1 and ochratoxin A in breast milk in rural centers of Yazd, Iran: Exposure assessment and risk characterization
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